dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0054125
Uniprot Accession X4YX01; X4YX01_DROME;
Genbank Protein ID NP_001287469.1;
Genbank Nucleotide ID NM_001300540.1;
Protein Name Wide awake
Protein Synonyms/Alias
Gene Name wake
Gene Synonyms/Alias CG45058;Dmel_CG45058;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
777RILDNLFTAVRLARPSysPTM 2.0;curated18327897; 19366988; 22817900
788LARPADVSELTLDPASysPTM 2.0;curated18327897; 19366988; 22817900
791PADVSELTLDPASAQSysPTM 2.0;curated18327897; 19366988; 22817900
796ELTLDPASAQRRNPKSysPTM 2.0;curated18327897; 19366988; 22817900
Sequence
(Fasta)
MEQDAAAGPA KKSGTTLSVD RAAFLLLRVR KVFKKKRQQR KERQAQQSAA AAASGAGGAG 60
GAGGGGGGSG SQSRPGSRKL PPPLLRSRTL PAIIVPGLPV VSLHTDKQTF QLDERLLGSK 120
SRSGSASGHR WSLLTRATNS SSMCSNNNPA SSSSSSSNNN NNLHMANNNN TLMVKSLNLP 180
KDDSNLVYRR KSSGSTPHQH QNAHHHHQQH HHLQQQQQQQ QQHQQQQLQQ QQMLQHLGDS 240
SLFQLSDDFE CHADGSLLLR IPAPHVVAAR AYRLAARKRA AASSEASTPM TREHTLHEMP 300
LAESACSGSA TGSGTTFTRL AKLLHQSSTL AGRSNLQPPP MADNAVQSLG RGLGLGLGEE 360
APRRLSWERR KDSSALQRSA SIDSFAEIVF SESPRPSLAV TGPGACASAS GGPSPFSKRP 420
SASSLYSTST SSSFASQMQA QLNVNYGDSA LGSGSATGGP GSGHHHGASG GGNGGSSASS 480
SRRESMLSPS STRRSKLTRI INALFSAVEH GHLEKARTIL ESTDVDVNSI NNDGLSALDL 540
AVLSNNRSMT RMLLQHGAVE GSQFSVDTIG TKLNGLLKDA ESRIHDLSGP EGLCPPVFAS 600
RPSISSIIIG NSSASVTGCT GSEVEKQIGI WERRVKGLRR LQLGWDQARP PDAPASVVVD 660
VTGDNSISVQ ILEPFEGAIG TKFKVQWSTR ADFNNVVGES ELLEWISFHG TMGAQCHISG 720
LTQGRRYFLR AACGNVKGWG TYRTSVPASV VPSTWRDLDN REDRFVGRHR ILDNLFTAVR 780
LARPADVSEL TLDPASAQRR NPKKKTTIKQ LFSVTTKFQK TLRRGIYFSC IIHCDDKVLV 840
TSEDFPPVIE VDESYPSALH MDYYWLMKVA CTWEDVKSLR SDMERNLTSA VHFRTKLLSA 900
VCQMQSALGI TDLGQLYYKP LRDAQGTVVL TCVQSVKSQK AVSILNSRWV PVSKLQKKLG 960
ALHEDYTINE LLISSIGDQL HYQQAALQRL EPGLYLGYLK MQCSIDQIQV VVPVKTPNVL 1020
PHCKVRENSH ITAEEWQVLH RYSSDPLRLP LDFSAQGGDG ASGATATTEV QRLFLYDLTN 1080
AMHKLFASMN IKIADATTHR LYDVEVIEHS PDISFLVVCP SAESSCAVPG QSELLLQRDD 1140
LASLSIQAFE MIHLRTYQPA IIQKYARLSC ILELDTALAT HSLREAFSSS ELQAAKERLA 1200
TLQELSASLT IVWKSVRWLM DVVAYARNKN AQPSLAMREI LDFAQQRQDE AVATSAGGSA 1260
NKQLLQLPIR ESKFSKTGQG RGSWPGPGTS EDQSQNKPEH SKSEQNLELS AITPVEPASN 1320
QVPTQQQQPQ QQSQQQQLLQ VSNISEYAGS ICSEVSFRKN SGDSMSSTYT SRSFYSAVDS 1380
ASDGNSTNSV FAIPPSRSDD TLADALRHSQ AVAAQRKRTS SNIASHTNPL ITVHSSSSAP 1440
YLAGSSVSLR SGNGAFATDL EHKPLKPATK AASSANLREG GPYLKSTLAE LRAVGGEEPV 1500
ASTSKASSMK SLSRQSSEED SASCSSLNAE QTSGIIQVYT AYSTGLASGT SLKIHVTPKT 1560
TAREVINLVV KQLNMAVVLK GNNGPIYGPE MLENFCLVAV IGARERCLRD DFKPLQLQNP 1620
WKKGRLYVRK KHELLAAIEH SNRKSHLI 1649
Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR003961--FN3_dom
IPR013783--Ig-like_fold
IPR000159--RA_dom

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50853--FN3
PS50200--RA

Pfam

PF00788--RA

Gene Ontology

GO:0005813--C:centrosome
GO:0005819--C:spindle
GO:0050811--F:GABA receptor binding
GO:0055059--P:asymmetric neuroblast division
GO:0098722--P:asymmetric stem cell division
GO:0000132--P:establishment of mitotic spindle orientation
GO:0045938--P:positive regulation of circadian sleep/wake cycle, sleep
GO:0061172--P:regulation of establishment of bipolar cell polarity
GO:0007165--P:signal transduction