dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0054121
Uniprot Accession X2JG37; X2JG37_DROME;
Genbank Protein ID NP_001285528.1;
Genbank Nucleotide ID NM_001298599.1;
Protein Name CG14619, isoform I
Protein Synonyms/Alias
Gene Name Usp2
Gene Synonyms/Alias CG14619;Dmel_CG14619;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
256AGISTTKTSICYFKPPhosphoPep 2.019060867
265ICYFKPITPPLQLRHPhosphoPep 2.0;curated19060867; 22817900
390GLGGGRLSVASRSNHcurated22817900
404HGSQAGGSSSNLQQRPhosphoPep 2.019060867
413SNLQQRYSSDLDNIRPHOSIDA;curated21081558; 22817900
427RVAAGYSSSLTRAAYPhosphoPep 2.019060867
428VAAGYSSSLTRAAYRPhosphoPep 2.019060867
589RDSGTSRSSIGTSSAPhosphoPep 2.019060867
590DSGTSRSSIGTSSALPhosphoPep 2.0;curated19060867; 22817900
Sequence
(Fasta)		MMLDIKKTRG FHKIPQASKL QSTTKTSSVV ATSASSQNEV PSPGGSAGSK VGATNPVRAA 60
NQRFFLVSSY KDPTFLKAEC DLAHAHVTTS KVKTTLQPHR RSRAGEDSRN NNYNTSRAPT 120
LINMRRPSLF NGNQQPTTTN STTINNTTSR NTTSNTSNGV LKYSVRSTTA TATSTSTRNY 180
GKLKPLNNNQ TTAGVAMMNG HTNNNNNNTR NSSNINNGGN NNMQRQQQQH DDISFIDSDD 240
PPATGGPEAG ISTTKTSICY FKPITPPLQL RHEQNQVQQQ EEQPQPSSSK SASHRYPRPK 300
STIIASAHSN FAASFEKFSG GLYRQTNGET NIESKTSSNA RRYGIDSLSI KASIEKFNNL 360
SGQKRQNPGS GSGIGPGSAT ASGLGGGRLS VASRSNHGSQ AGGSSSNLQQ RYSSDLDNIR 420
VAAGYSSSLT RAAYRTTATM NSVSTPVAVT SELGGPISGD GGETATAMGQ PTSKVTVRGA 480
HSNRQPIECD SVVLTNKASK DATTAATPTV ATATATHTPA TSSVSTVTVT AAAPNSASDS 540
VSRSLARSPI SSTLARSGTG SSSTARSVLP PMTPTSSRYW DRDSGTSRSS IGTSSALNSS 600
SLKHNSDDGY KTASSSRDEK SEGLCGLRNI GNTCFMNSVI QCLSHTQELT RFLRSHHGSR 660
SLSTKDQQIL HEFAKLIQEM WTANVHTVTP MELKRAFSTK HRMYSDYNQQ DAQEFLRFFL 720
DSLHSALNSG VKGETLNIDD NLSDNKKADL TWEWYTRHEN SLVRDLFVGQ LKSTLKCTTC 780
GNTSVTFDPF WDLSVPLPSS SRCKLEACLD LFIREEVLDG DEMPTCAKCK TRRKCTKSFT 840
IQRFPKYLVI HLKRFSETRW SKLSNIVEFP TSDSELNMGS YGANSNSNVH YSLYAISNHM 900
GSTAGGHYVA LCKHPVSRKW HEFNDNIVSD ALSENHLVSS SAYILFYERT 951
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0070628--F:proteasome binding
GO:0004843--F:ubiquitin-specific protease activity
GO:0002785--P:negative regulation of antimicrobial peptide production
GO:1900425--P:negative regulation of defense response to bacterium
GO:0045824--P:negative regulation of innate immune response
GO:1901800--P:positive regulation of proteasomal protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process