dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0054120
Uniprot Accession X2JF73; X2JF73_DROME;
Genbank Protein ID NP_001285288.1;
Genbank Nucleotide ID NM_001298359.1;
Protein Name CG8184, isoform H
Protein Synonyms/Alias
Gene Name CG8184
Gene Synonyms/Alias Dmel_CG8184;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 18
PositionPeptidesSourceReferences ( PMIDs )
509GENASVTSGNASPRRSysPTM 2.0;curated18327897; 19366988; 22817900
513SVTSGNASPRRDNSSPHOSIDA;SysPTM 2.0;curated21081558; 18327897; 19366988; 22817900
519ASPRRDNSSDGATGAPHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated21081558; 19060867; 18327897; 19366988; 22817900
520SPRRDNSSDGATGAGPhosphoPep 2.0;SysPTM 2.0;curated19060867; 18327897; 19366988; 22817900
543EHIGGAGSGAGLLDIcurated22817900
555LDIGGARSSLSGGSSPhosphoPep 2.019060867
1935NKSQSGGSPPIPKRTPhosphoPep 2.0;SysPTM 2.0;curated19060867; 18327897; 19366988; 22817900
2788DEDVDEHSETDVDEEPHOSIDA;curated21081558; 22817900
2790DVDEHSETDVDEERSPHOSIDA21081558
2853DVREEVQSVMDAEIEPHOSIDA;curated21081558; 22817900
2879SNNRPRRSAAVNASGPhosphoPep 2.0;curated19060867; 22817900
2937YLYERLGSGLMPTPPPhosphoPep 2.0;curated19060867; 22817900
3262ATGGTRRSSIPVLISPhosphoPep 2.019060867
3430IRNRLQGSSGHTNSSPhosphoPep 2.019060867
3440HTNSSRTSGSALINAPhosphoPep 2.019060867
3472GSIFPRPSANRTPAPPhosphoPep 2.0;curated19060867; 22817900
4082QVVNRLRSIFDDHPAPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
4308LSVALPVTPSKPRRKcurated22817900
Sequence
(Fasta)
MKVDTVKLKK GSSELTAECR ELIDELTKRR TRAELLEFLD TVHVWIYGKC ELYHWIEILD 60
RFDKILEEAS RHVNGNEFVL QCDTNFQETD VTLLLHVLNF TTLLIEHSFS RHLYNSIEHL 120
TVLLSSQNMD IVLAVLNLLY MFSKRSNFIP RLPFEKKELL IVKLFNIAER WGDPNYGLSL 180
KDCCIGEPKL EFLYQLCIDY VDEHGHAAQL EIPDMMDLCH TASAPEVIKT IAGQISKPSE 240
AIKMRIAHRV RLISGFNNYK LRLQFVQARL QAVSILIYSN ALQDNTDKVL YAGFGEELCE 300
LIDKEDVHLV EIRAAVLRTL TSMLHFDRNP NVPRAGSRLM KIVHYTGAER QGGTLPLLVR 360
DCIDNLTTHG LTERYPLILA TSLFSLLYHL ASYEMGGTAL VKSGMMQSLL CVISWPGVDL 420
EHITFVTRAV RVIDLITNID IARFHQNNGL NVFIDRLEKE IKSCCKALAD IGITLKESTL 480
RDDHKLDTSL DHVDEDVEDG SGENASVTSG NASPRRDNSS DGATGAGSIV YRAYHEHIGG 540
AGSGAGLLDI GGARSSLSGG SSGTSGMGAG SINRDGSAAR PPAIMYPTNS YYARPLAERK 600
AELSSQLPSS LAPKKPSCVT QRAALLKSML NFLKKSIQDH AHFSNMRNIM ETSLTQSLRH 660
IIANAEYYGP SLFLLATDVV TVYVFNEPSL LSSLQDLGIT SVMLKALLQK DVPATREVLG 720
SLPNVFSALC LNERGLFEFL SYDPFDKVLK VLLSPDYLVA MRRRRSSDPL GDTATNLGNA 780
MDDLIKHHPY LRADATEAIV RLLNELVRLG SDPSFICWRA NKESSGSGSG SGSHGGGHHV 840
ASTPSPMVMV AGTGSASSVL QGAADTNDSS GDDDDDDDEM SSASQQQQQP TTPGQGGGPS 900
TPRTQQAGGV VGSGAGATGT PAAASQAVKV VTPPEREAIP LIDYILNVMK FIEAIFSNSP 960
NGDHCREFVL HGGLKPILQL LSLPNLPVDS PVSTTSQAVA NVCKAILSQA QETKVLDVAL 1020
KQLADIVAQL KPLIKHFTFP GGSVLLAELV CCQRLEDGFA NAEYTPILHN MSFVHGYVVM 1080
LVHLCRNASN DMRTILLKRW GVNRETGVQL LQQLVQLYIS LVWESTILLN LCSDEPTQHP 1140
DLIWDEIAAQ MSAAAGTADP LTEAELSRKL ERAAEFRTKY TPEEQFRYIK SLLAASSRLG 1200
RALAELLGTL VKLSVGSPQT RQRRINDLIS NITKVPTPEA REIARILSSI LVNGFSHESI 1260
LPKPVPKLKL TFLICSVGFT GPMLFDDKRS AFHLMISQFC AENGLKAFFE MFYWALSLDN 1320
VSQKFEFDQW ASMEDLMQSH EDDKRDCPEG TGEFLDAWLQ LLEKMVNPRA MLDSPYTMSP 1380
RLNYMPDSVP FEPVFYLIHI HQLAMQALRR IWARRPIPNY GPSMFETMIL ILKHLIKSHQ 1440
TLLDRYHTRM KEIKFENLYI RSTDDGLNAD HIKTLTDMGF MHYHVIEALR TNASLEEATD 1500
YLLNNPEASS LSTTGGQSSS SAPPPPPPPS ASTMDIDVDV PADGESTQSK SSTSPNSSYD 1560
YKHLKLMPSL IFDRFCDEAI SRAFEFMEAI PDTVNSAADL IAVLYRRHNH LNKQVFVTNF 1620
VRNIIQWVDF TLQLFEPAKT TGSKASRLEE CLTGMTATRL FVRLKTSTLL LEENYSDLHR 1680
PLVEAITAQD AMVSLVKLLD CMSQWMLEQS TETNTGQQRA TVPRWVQNLV DLIDAIDSIS 1740
HILQRKANMR AVSSDVWRWY DASTGKWNAY SEANNELIRN AYAAGERWLY INIGRQRCTV 1800
SLNCMTQVSE ASGTHRPVCP ALKLSEAITS LNNPVALHKV EHILNRVVRT APDGSGTVHS 1860
DELISLRQLV NFTDGQQPQQ SENSANPSEE ATSEDGPAAA NSGSPPATMT TRSKTRQKSA 1920
AAAAAAKNKS QSGGSPPIPK RTQKIILNEE QVGLSKFDCG RIIGSIVDLL QPSHQMLNET 1980
KLSLLRLCAR LTRNYDNAQV FIRRGGVRML LHLQQACSFM GFPTYANIIL RHVLEAPPVL 2040
QEAMERVLGM RAAGIVPVGH RDLIYVLTQV SSAVSRNPQI FVAAAKEMLK GEYLINTNST 2100
TLADDARVMV KSKFGQQPTA AAGGATPHNQ TPTPPPAAKD ELKDDPQVQS SVAVLKELLH 2160
GLVQPCWHYG GTGSLDRGQG AAELLQPDQP PGTAQGCHDD ELYFRFQETP APVSSKKQSS 2220
SGGGAAAAGQ TGQATEKFEP CCCTWHIPTS GHTHAKPTIS RATLLKLLAD STRAYQSLVP 2280
RVLLSHVYTP ADSPLISAPQ QTFLGVLLDR FLPITQRHHV PEVSTMTRVL ICSLSDCYQQ 2340
PGVQVHVAEE LHAAVARALA QPDSAEKHTR LQVLMSLFPN LIESPMLYDK VHMHRNNMYR 2400
VLLRQGVMTY LTKVAQYKDL SNHNTLSTLA AILRPMEILL RFSVSTTTLG SKRILFGSGG 2460
PGGPNASGNG NNTAGGSSGN GPGSGNTYGT IINRRLYPRL AARTGFGSAM ERSNAMGGEH 2520
VLRDIIRNVL SDRRHAFEFI FNSDDMAVDS EDAAAPGSGV GGGGSGAGSV GGGVSGSVSG 2580
NSSAAVIDVV EERSNGGDTN DPPANVSSAS SGAGQSSTSG GPVRPVVNFD QLWDDFLQSE 2640
GLRLASRSGG GAGSGSGSVG ASSSGQQNGS NTTASSTNSG NNSGIGNLRL RTNPDVDVGS 2700
GNGSGSGSGS NAGVVNDNGI SGGGGSDGAS TSSDTGAPGG ARDLNASLLG DVSTSESDSD 2760
PSTENDERNE EDEDEDDDAP DEDVDEHSET DVDEERSRQF IEVFDHIYEP ESSETASNDA 2820
DVDNDDDDDE DDVDDDDDDD EDNDDDVREE VQSVMDAEIE NRIDIALALV SSNNRPRRSA 2880
AVNASGDGSA NRTNPDDEVD DEDDDVDADP DGDPDVDPIS GPSAAQAEAY LYERLGSGLM 2940
PTPPVGFRVR MNSSIAQPLD IDVNGGNAGS GSNAGATGSS GGSGQRSSTG GTTASIGAIA 3000
SAALRPSSGS WMAPDFNFIR ISGGDSSMGS GPAIGGNANG GDMNVFITPS MSLERAGGAP 3060
GSGQTMSELL NEQPTGAGGG GGGGSASGVG GVGANGGTTG QHPNATLCTN GVRRRLLYLD 3120
QQYCVCMPTH QNPTEETQME TFTQDALHWW LEEATLLDME SQTDACLYAA HFLLPHLIKE 3180
LKAAHQQRKQ EEAARQSTTP ASGSNASATS SSTTSVVGTA APTATSSIAS GLLANAVSAG 3240
SGSSSLVVPP VAASATGGTR RSSIPVLISS TLGPSSASSA TSATGNGATS DATTTTGGPT 3300
RNFSSVDSNV SSETQTTTRP PRQRGGLRQQ SQLPFNIYAE IDLTNEQDSE GDRSTSTTTG 3360
TAADGAESQS QHNSSSTAAQ VAVPQHQRHP PVPLLPSSGR PSRPHTRLDE TELLLLQLTD 3420
RQIRNRLQGS SGHTNSSRTS GSALINARPN RDLPACLQRH DHPAGSIFPR PSANRTPAPT 3480
LVSMPTPMSN AALEQLNVTA PDVVRTDRNF ALPSSLEVDV DVLPGIVDLP QQEAQPEDDQ 3540
LLLPPPPPPP PSDTTPLVHA EDDLWPGTVV SAGTREESSA PAVATESTEA VNESNQPEPT 3600
PESSESTSPN PQAPSAEPTP LEPGAAVDAS VGAQTPATTE EAASTAGASG TTATITDMSP 3660
EVRAALGDLE VPEGVDPSFL AALPSEMREE VIQEHLRMQR IRQRAQQNAI QIAHDSLVEV 3720
NPEFLAALPL NIQSEVLMQQ RIEQQRQAAQ TANPEDPVDT AAFFQNLPEN LRQAILTDME 3780
ESQIASLPPE LAAEAQFLRR DWESRNGARM DAHPPSNALS RFQTTLQSLD DTRWHSSIWY 3840
DASGNAQPQH HQHTTIVHQH PHAHHAPNMG KPLALLMMED ENILLDPDSL ATLLLFLFVE 3900
DQKVNSMRLH RVIRNLCHHE PTRDWIISAL ISIIQKTNED NANFGAGQAG GKPEWLKLRV 3960
DAAFGYKSNI FLINRLYEGS ARSISINPQA AQMIVRNCLD LLFVLAKHYP SSFVPFNRDV 4020
KARRILSAVF GMPSPTAGSG GGAGSGSAAS GGLTGYDDVP PGGTLDFRSR FCRYQVVNRL 4080
RSIFDDHPAP KPSVPLDEAP STSKAAAAKA AATAKVSTAG SQNKHSVPYQ TNAKNFWDVV 4140
LNIDQQTQVR LANVAQFPLT SQPAWEWQPN TADFLSFSES PFGQLLEMLP YKVICRSPHL 4200
TDMLVKLLAS LSTELPKEEE LLPLSDQMPP LVPIGPVQRA GAAAAAAHPP PPQPPAENTA 4260
TATEIGDGLA ANIEEQASPA SGNPASGDSN AGAKRTQLPT LSVALPVTPS KPRRKIYSKN 4320
FSQLQLVIEV LTHQCGTTEG LDNVAKLIVN LTQCSQASSA IFIQYLTAAI LGLAEEVRQA 4380
IQMLLNEIRM YNIHQGGAGT TSQAASTSGA AAATASYVPT VSGASLLPNL AVHEGIMQDR 4440
FTAEHVIISA PKNAKPTCEL QLPSMKKLMS NSSAQPYFLR TLKIFMQVRD MYEAQNGLST 4500
GGGVACGAGD NDDDIIDIEG DGGASGGSSS DMAPGSASTI SPPPPMETNQ IAQDGDDDEE 4560
DDDEARSFPG VGNHAVASAS KSTKPTLSQI LCLDVLWNTL SECLVALEES KDEFAVLVLQ 4620
PTVEAFFLIH ASHRGASKKS GRSFMPNAAG FGLRAAAGAG AIGGLGAAAP SAQEYSPFMD 4680
DVSSANTPSS ASFDDEPRMQ DASTNTPLVT NPSTSTAMSA HEAQLRQDRQ KFLQFAEKHR 4740
TVLNQILRQS PTHLSDGPFA VLVDHTRILD FDVKRKYFQT ELERLDEGIR REEHTVSVRR 4800
VTVFEDSFRV LYRLGPEEWK NRFYIVFEDE EGQDAGGLLR EWYVIISREI FNPMYALFCV 4860
SPGDRVTYMI NPSSHANPNH LSYFKFVGRV IAKAVHDNKL LECYFTRSFY KHILGKQVKH 4920
TDMESQDYEF YKGLDYLMKN DISTLGYELT FSTEVQEFGV TQIRDLKPNG RDTAVTEENK 4980
FEYVQLVCQL KMSGSIRQQL DAFLEGFYDI IPKHLISIFN EQELELLISG LPDIDIEDLK 5040
ANTEYHKYTS KSAQIQWFWR ALRSFDQADR AKFLQFVTGT SKVPLQGFGS LEGMNGIQKF 5100
QIHRDDRSTD RLPCAHTCFN QLDLPMYKSY DKLRSCLLKA IHECSEGFGF A 5152
Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR004170--WWE-dom

PROSITE

PS50237--HECT
PS50030--UBA
PS50918--WWE

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA
PF02825--WWE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0033227--P:dsRNA transport
GO:0016567--P:protein ubiquitination