dbPAF - database of Phospho-sites in Animals and Fungi

Protein
Gene
PTMs
Sequence
Keyword
GO
TOP

dbPAF Protein Information

Tag

Content

dbPAF ID

dbPAF-0054118

Uniprot Accession

X2JEM2; X2JEM2_DROME;

Genbank Protein ID

NP_001285158.1;

Genbank Nucleotide ID

NM_001298229.1;

Protein Name

Sec16 ortholog, isoform I

Protein Synonyms/Alias

Gene Name

Sec16

Gene Synonyms/Alias

CG32654;Dmel_CG32654;

Organism

Drosophila melanogaster(Fruit fly)

NCBI Taxa ID

7227

Functional Description
(View all)

Phosphorylation Sites

dbPAF PTMs: 18

Position	Peptides	Source	References ( PMIDs )
588	RRADGEDTSDGEQQV	PHOSIDA;PhosphoPep 2.0;curated	21081558; 19060867; 22817900
589	RADGEDTSDGEQQVR	PHOSIDA;PhosphoPep 2.0;curated	21081558; 19060867; 22817900
707	RAAVGRRTTASLDLE	curated	22817900
708	AAVGRRTTASLDLES	curated	22817900
715	TASLDLESDESDEFL	PHOSIDA;PhosphoPep 2.0;curated	21081558; 19060867; 22817900
718	LDLESDESDEFLQSE	PHOSIDA;PhosphoPep 2.0;curated	21081558; 19060867; 22817900
724	ESDEFLQSERERDRE	curated	22817900
757	HYPYEGETEDSVRGA	PHOSIDA;PhosphoPep 2.0;curated	21081558; 19060867; 22817900
760	YEGETEDSVRGAAHH	PHOSIDA;curated	21081558; 22817900
817	RRSNKYHSGGEDPDR	PHOSIDA;PhosphoPep 2.0	21081558; 19060867
832	SYDHSRRYNNSNYEG	curated	22817900
835	HSRRYNNSNYEGESD	curated	22817900
841	NSNYEGESDNPEYNH	PHOSIDA;PhosphoPep 2.0;curated	21081558; 19060867; 22817900
857	GDAELDGSGGRSSKT	PHOSIDA;curated	21081558; 22817900
862	DGSGGRSSKTSRHRR	curated	22817900
870	KTSRHRRSAAEEDFD	PHOSIDA;PhosphoPep 2.0;curated	21081558; 19060867; 22817900
1639	PILINRVSFASPPNA	PHOSIDA;PhosphoPep 2.0	21081558; 19060867
1642	INRVSFASPPNATSK	PhosphoPep 2.0	19060867

Sequence
(Fasta)

MLHNNAPWLP PHQQQQQQAP QQHPTPQQQH AMPQQQQTLP AQQQQQQVYA SQMFQQHQPN 60
YWPEDQHQQQ QQPQSLNYNN YFPGQQQQHP MQQQQLPPQQ QLPPQQQQPT QQQHTIQQQL 120
YYPTQQQPQV PAPAEPALDS FDNNNSGGGG GGGRSDGWGD WGDWNDNSNN NNSNGTDGLL 180
EPTGQLLEDS FNVQSSQGSW QAFATSNNVN NNGELPPPAN PQSTSLQQQP LNQQSIPLLH 240
QQPQSPPELG QEPELDAIVP PQAFQNQPPT AAPPPTSLTS FSAQMTAVGS PIYAVGASSA 300
HSAGVGASPA PPTGVVAPPA HLAGIGAPPA HLAGVGASPA PSALVGASPA PIIGVGAPPV 360
GAPPVGAPPA DATTIAPPAA LPPSIVPSSG SNPFKRSTGL NKRVNIMADP AAGAPSPPAP 420
AAAIAPVAPV APIPPPADQL FGMPAEAHGE GFNLIAAPPV EASLGTPLSA PIPAPIPVPN 480
ASLYASPAVP QAFAHLEPDN QEVLSAPNDE RAQYLQTSHL SEQLGEGEAD QDAGLLPPPG 540
LSRLVLGQPE LDSQQQRQVT GATEQPPLNV AQAAALHMQE RRADGEDTSD GEQQVRNIQT 600
PPRRVVTGVE TNAPSLREQR EVVLDGENLE DREAIPPPTL AELPTTSVHH NILPDEAEQL 660
HHNNPPQAMT PLNAQQPHQQ QSTLQQQHQQ HSTTQQEKKR AAVGRRTTAS LDLESDESDE 720
FLQSERERDR ERERRDLMEE RHSRGRSHSH YPYEGETEDS VRGAAHHETK SLRETHHKRN 780
HDSARSRRHQ DPKVERERER DRERDRTWRR RSNKYHSGGE DPDRSYDHSR RYNNSNYEGE 840
SDNPEYNHMG DAELDGSGGR SSKTSRHRRS AAEEDFDDYE RERNRSRRST KPQSSAEKSR 900
SSGGRRNYEN SGRSARADDG RRRYQDQRNP GAQYPVSATG YVPYGMYEQM SRNPQVYADM 960
YAKFYGQMIN SMNAAVSAAA SKGGVPAGAG VIPGLMPSAV PVSAAQLVAA TSGGSVSGSS 1020
EAAMLRERER YTHAYITQAN EFHRHQYKEL IYQQQQQQQQ QQQQQQQRED HLNSSFSVAE 1080
DNASFYGSHG GGSIYNQYQS YPLSSARSLS NLNGDGRNSR CGPYYAGSEC GLDIRAAADA 1140
APSTYGGVAG TAGPVTNTAV ARPPRRRTPL QFSRPHLVAS YAMSLLLKVK PKYAGRGRLR 1200
NDVEVAPPRI RDGTSSLLRM YPGPLQGRKL HKDKIISFCK EQIRLGPTKG CTALYATQKK 1260
PQGSVTKYRA SHALMWHLLI LLLRQNGYIA DTDVGDLLLE NQQEYPYDPS EFEAENEPDA 1320
DAEQDAAAPA DKTVDSDLDS ESAAGVTPAE PLAAGAATSS INGADAANAA TPLSEQAATD 1380
KFRSYVLRGN VEEALQWATD NGLWTHAFFL ALYEDRYALT DVAQKFLNRA IKANDPLQTL 1440
YQMKSCHTPA CVSQLRDEQW GDWRSHLSIL VTNKSRQPEY DRSSVVALGD TLFQRGDIYA 1500
AHFCYLVAQE EFGRYDSSAT ELTTLTANVP RLILLGSSHY KHFNEFASNE AIIMTEIYEY 1560
ARSLFDPKFS IAHFQHYKFL LATRILDYGQ HFRCTNYLEQ IARHIELKPE SYDSNFIQRV 1620
CGLAERLRYH DPILINRVSF ASPPNATSKD SAAAEEKAWL RQLRSLAYVQ PQQEQLQQLQ 1680
QNQQVQQEQN DIDQQFAEVN KQFRELNMQY ESNSNMENTL QPQLPPVDQQ PPQQQQQVLS 1740
ESYQQPTQQY YEPPPQAPTE SDPYGQGQPS YYDPNAGQLH YDPNAAQHQY DQQQPQPQPT 1800
PSYGQIEPGT EAYQPGQATA DPAAVPSGYG YDYWSGTQQP PYGDEPNENQ AALKDEEEED 1860
EEQDEQQILQ YAKQQILQQT KQQQLQQEQH TRSNGAASIN NRFKSNALKQ ERSSGSLRKR 1920
QEASRTATIA AAAAAIAQIT PATVAAAATP PAASAKAFNL NDVSSFSSTN KRHQATSSSN 1980
NRSSSNQAAA AAAATKAAAI ATVPAAPNQL LSCRKSNSQN SPYLATPKTL TTPTRFIAAK 2040
AATVTATPTA PATSTTTSTT IGARGSSTKR VYFNLPSTIA ESEQEFEHEL DYDEEMEEEN 2100
SMALAQAKPN VHLARKPHIV FNGTYPIDMP LTQGQSQLKS NSYDPEANAD RGDLQRYRNY 2160
MLHDYVIDED AEGEEQAEEE GEEDEYGDGD EDLFPYADDD ESFDDGDYYT HQLLNKYGII 2220
PSGEKQRVER TPASVEAATS AAQPQHVWSM KELIANPAIP LNYKKMCSEV EQSLSRFENY 2280
LDSKKEQQVP PGAAVRTFDI DAPTRRGHRS STSTNAGLDL RSKKKL 2327

Fasta Sequence

>X2JEM2|Sec16|Drosophila melanogaster(Fruit fly)
MLHNNAPWLPPHQQQQQQAPQQHPTPQQQHAMPQQQQTLPAQQQQQQVYASQMFQQHQPNYWPEDQHQQQQQPQSLNYNNYFPGQQQQHPMQQQQLPPQQQLPPQQQQPTQQQHTIQQQLYYPTQQQPQVPAPAEPALDSFDNNNSGGGGGGGRSDGWGDWGDWNDNSNNNNSNGTDGLLEPTGQLLEDSFNVQSSQGSWQAFATSNNVNNNGELPPPANPQSTSLQQQPLNQQSIPLLHQQPQSPPELGQEPELDAIVPPQAFQNQPPTAAPPPTSLTSFSAQMTAVGSPIYAVGASSAHSAGVGASPAPPTGVVAPPAHLAGIGAPPAHLAGVGASPAPSALVGASPAPIIGVGAPPVGAPPVGAPPADATTIAPPAALPPSIVPSSGSNPFKRSTGLNKRVNIMADPAAGAPSPPAPAAAIAPVAPVAPIPPPADQLFGMPAEAHGEGFNLIAAPPVEASLGTPLSAPIPAPIPVPNASLYASPAVPQAFAHLEPDNQEVLSAPNDERAQYLQTSHLSEQLGEGEADQDAGLLPPPGLSRLVLGQPELDSQQQRQVTGATEQPPLNVAQAAALHMQERRADGEDTSDGEQQVRNIQTPPRRVVTGVETNAPSLREQREVVLDGENLEDREAIPPPTLAELPTTSVHHNILPDEAEQLHHNNPPQAMTPLNAQQPHQQQSTLQQQHQQHSTTQQEKKRAAVGRRTTASLDLESDESDEFLQSERERDRERERRDLMEERHSRGRSHSHYPYEGETEDSVRGAAHHETKSLRETHHKRNHDSARSRRHQDPKVERERERDRERDRTWRRRSNKYHSGGEDPDRSYDHSRRYNNSNYEGESDNPEYNHMGDAELDGSGGRSSKTSRHRRSAAEEDFDDYERERNRSRRSTKPQSSAEKSRSSGGRRNYENSGRSARADDGRRRYQDQRNPGAQYPVSATGYVPYGMYEQMSRNPQVYADMYAKFYGQMINSMNAAVSAAASKGGVPAGAGVIPGLMPSAVPVSAAQLVAATSGGSVSGSSEAAMLRERERYTHAYITQANEFHRHQYKELIYQQQQQQQQQQQQQQQREDHLNSSFSVAEDNASFYGSHGGGSIYNQYQSYPLSSARSLSNLNGDGRNSRCGPYYAGSECGLDIRAAADAAPSTYGGVAGTAGPVTNTAVARPPRRRTPLQFSRPHLVASYAMSLLLKVKPKYAGRGRLRNDVEVAPPRIRDGTSSLLRMYPGPLQGRKLHKDKIISFCKEQIRLGPTKGCTALYATQKKPQGSVTKYRASHALMWHLLILLLRQNGYIADTDVGDLLLENQQEYPYDPSEFEAENEPDADAEQDAAAPADKTVDSDLDSESAAGVTPAEPLAAGAATSSINGADAANAATPLSEQAATDKFRSYVLRGNVEEALQWATDNGLWTHAFFLALYEDRYALTDVAQKFLNRAIKANDPLQTLYQMKSCHTPACVSQLRDEQWGDWRSHLSILVTNKSRQPEYDRSSVVALGDTLFQRGDIYAAHFCYLVAQEEFGRYDSSATELTTLTANVPRLILLGSSHYKHFNEFASNEAIIMTEIYEYARSLFDPKFSIAHFQHYKFLLATRILDYGQHFRCTNYLEQIARHIELKPESYDSNFIQRVCGLAERLRYHDPILINRVSFASPPNATSKDSAAAEEKAWLRQLRSLAYVQPQQEQLQQLQQNQQVQQEQNDIDQQFAEVNKQFRELNMQYESNSNMENTLQPQLPPVDQQPPQQQQQVLSESYQQPTQQYYEPPPQAPTESDPYGQGQPSYYDPNAGQLHYDPNAAQHQYDQQQPQPQPTPSYGQIEPGTEAYQPGQATADPAAVPSGYGYDYWSGTQQPPYGDEPNENQAALKDEEEEDEEQDEQQILQYAKQQILQQTKQQQLQQEQHTRSNGAASINNRFKSNALKQERSSGSLRKRQEASRTATIAAAAAAIAQITPATVAAAATPPAASAKAFNLNDVSSFSSTNKRHQATSSSNNRSSSNQAAAAAAATKAAAIATVPAAPNQLLSCRKSNSQNSPYLATPKTLTTPTRFIAAKAATVTATPTAPATSTTTSTTIGARGSSTKRVYFNLPSTIAESEQEFEHELDYDEEMEEENSMALAQAKPNVHLARKPHIVFNGTYPIDMPLTQGQSQLKSNSYDPEANADRGDLQRYRNYMLHDYVIDEDAEGEEQAEEEGEEDEYGDGDEDLFPYADDDESFDDGDYYTHQLLNKYGIIPSGEKQRVERTPASVEAATSAAQPQHVWSMKELIANPAIPLNYKKMCSEVEQSLSRFENYLDSKKEQQVPPGAAVRTFDIDAPTRRGHRSSTSTNAGLDLRSKKKL

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR024298--ACE1_Sec16_Sec31
IPR024880--Sec16

PROSITE

Pfam

PF12931--Sec16_C

Gene Ontology

GO:0070971--C:endoplasmic reticulum exit site
GO:0000139--C:Golgi membrane
GO:0016020--C:membrane
GO:0017016--F:Ras GTPase binding
GO:0034198--P:cellular response to amino acid starvation
GO:0048208--P:COPII vesicle coating
GO:0007029--P:endoplasmic reticulum organization
GO:0007030--P:Golgi organization
GO:0070863--P:positive regulation of protein exit from endoplasmic reticulum
GO:0070973--P:protein localization to endoplasmic reticulum exit site
GO:0003400--P:regulation of COPII vesicle coating