dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0054116
Uniprot Accession X2JEI9; X2JEI9_DROME;
Genbank Protein ID NP_001285496.1;
Genbank Nucleotide ID NM_001298567.1;
Protein Name Rho GTPase activating protein at 19D, isoform D
Protein Synonyms/Alias
Gene Name RhoGAP19D
Gene Synonyms/Alias CG1412;Dmel_CG1412;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 41 (View all)
PositionPeptidesSourceReferences ( PMIDs )
229TPESNRLTMSTHSPScurated22817900
234RLTMSTHSPSLLANGPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
349QHRHPALTGGSSSIDPhosphoPep 2.019060867
352HPALTGGSSSIDFGDPhosphoPep 2.019060867
354ALTGGSSSIDFGDMAPhosphoPep 2.019060867
665TTTVKKQSVLYESLQPhosphoPep 2.0;curated19060867; 22817900
668VKKQSVLYESLQQHPPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
767VRRYKPLSSSSFDEGPHOSIDA;curated21081558; 22817900
768RRYKPLSSSSFDEGKPHOSIDA;PhosphoPep 2.021081558; 19060867
769RYKPLSSSSFDEGKPPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
770YKPLSSSSFDEGKPMPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
899AHGSRRASMSSDMRSPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
1182IPDKDLGSPKSKNWKPhosphoPep 2.0;curated19060867; 22817900
1198LLFRRGGSGSGGVSHPhosphoPep 2.0;curated19060867; 22817900
1650SANFKKRSTGGFLGSPhosphoPep 2.0;curated19060867; 22817900
1651ANFKKRSTGGFLGSRPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
1667SHQTRKASLDEKDSGcurated22817900
1673ASLDEKDSGQSSGSLPhosphoPep 2.019060867
1679DSGQSSGSLGHSLGVPhosphoPep 2.0;curated19060867; 22817900
1683SSGSLGHSLGVGINLPhosphoPep 2.019060867
Sequence
(Fasta)		MLQNSNGAAA AHSAASAVAT PAAAASAAAA AAAAAVAAAA NNAALAASSI QPKLIVIRRR 60
PNQGFGFTLR HFIAYPPEDD QASSSASGLV SGSATAATAA SVSTNWPQEA SSAAGSNSGS 120
SSSVGVAGIT GLEPTSPTSL PPYQVKAMET IFIKEVQANG PAHYANLQTG DRVLMVNNQP 180
IAGIAYSTIV SMIKQTPAVL TLHVVPKECD VLQMHYTSIA HTPESNRLTM STHSPSLLAN 240
GSHKTTFPAA AAVAAPPHQH QQQQQQLISY PAVAAVTTST PAGSPQSQSQ SQSHSHPNTH 300
HAPSLHGGSR SGSITSTASG GITVLSQPFY PQQQQQQQQQ QQHRHPALTG GSSSIDFGDM 360
AHGLRQHQQQ QQHLYQQQQQ HHQFMRANQP PNLTVLSASS ATNTPTPTAR QPKSATSHNQ 420
ALYAVGAGPS SAAGSGSGSL SGGSENSDLM IRLRESIKQK EEFLKSPVPA SMSSASSING 480
NQAQSSSPAQ QQHLQQHQQH FFPSHTPPGG VQVVVPPPRS RHQVMLKQQQ QQQQQHQQHH 540
VLGYDMYHSG GKLVQRSSTA PGSVCHQHQQ QQQHHLYHQQ QHQQLQQTQH RQVMINNNAK 600
YAKDLDYFET LQETGVTNKV FERKLVSHMS KGFDPFKPLS INTSALESSA STSSTSATTT 660
VKKQSVLYES LQQHPLAKYH QTQQQTTTTT TVDGQTSSRM ELHKATLANA TIDPVPVGSS 720
KFVTLPDKPD KGSSVATLAD IAESSAAAIV DSASGSGNVV RRYKPLSSSS FDEGKPMRRI 780
SYLRATNNET DFNAEAAAGG DAAATGASGP ASASAASSAP GPTPSSAPAP APAPAPLPIS 840
IPIPVAAVVE PQKTKSLVEE HPDPTYDVIG GTGGGHEFIE TPNGLEDVRL SAHGSRRASM 900
SSDMRSSIHI DAELNGKYVP NELEAFETEI EIKSSCINGK RMSEYRSWRQ VKLEIKGDLL 960
RIYSGRHAKS EHNVIELDIR NFKFFDESMD KKKYLIRMQS KPSPSGAHLA SLGNELNLDE 1020
GHDKLLTSSG SSSANEPAAN AASALTASTS SSTCSSGPYT EILFKTKSSN EMKRLFGLLQ 1080
WKDSLNYDDN EHQPQGKQLA EPQKTVASAS YLDDVQGGAS AADSSPLSSH SGGIADASGS 1140
HHVSALPAAA AIVAATSDSI SPVMKARKSS SHKHIPDKDL GSPKSKNWKD LLFRRGGSGS 1200
GGVSHHDLAS PSACAAKQIG SIGVPLRSCP MSKVNAYVPH LVEVCTNIVE TKGLGVVGIY 1260
RIPGNKAAIS ELSELVNTKD FQFESCASDD RWEDVNVVSS LLKLFIRSLP DALMPASYYI 1320
NFIEADKKFG LERIVLLREI VESLPRHPYE TMKHLIRHLC RVSGNCDVNR MEPKNLAIIF 1380
GPSIIRTPND TLETAVKDMK HQCRIVELLV TQYDYFFEGG SLPDIAEVSG GTAAVSAAQP 1440
QQQTQEDQTS MLLHNLSKIE RITERETTRT SRFMPQLRRK THGKRSAVNS DTYSGESVLV 1500
SGSSSNTTTT TTTTTHTTSS TSSSNTITTT ISTTTIQQRR AQRKAVQSIC DQALILLLPT 1560
PVSSVSLPFQ SLDYAKASAS ASASASSTAS TSSSSTLHSG GKASASSSSS STTKFSSSSS 1620
SACSTTAVAI SSSISATSSK LLSANFKKRS TGGFLGSRSS HQTRKASLDE KDSGQSSGSL 1680
GHSLGVGINL AKEQQRSSVD ISILLTDDDS SSRLSDTGSM SLTTITDTLD SKLRNLRSGS 1740
ESNDENGSPE FPKNRRHTLG QPLHMHSENI PYADESPERL FHQFCNPLET APLSLHLSRS 1800
CTATNTIGGD EKPSKQSGGV APLPPSLLKA AHKLQHSATV PIHQGSSTAP TSGAATPVGT 1860
PTGSGGAGAI PSRSSSSSVT TLTKSIQPRF SNYLSYERGN AAAGGAERVV GSAGGAASDD 1920
DSEGSTTSDP KEKLLLGERP SPSFFIERYN KKRRDHRLFR SASFNCRNYS TRHITAQTSG 1980
GVAAGVSGGV AGAVAVGVAC CQALSTTGLT KDEKTDMNLT KKRQIQNKQN RSIKRRHTVG 2040
GPHDYSASNG GCSNHSHGHD LAAINYNHHN RHHQQQLLKL GSATSGGGGS GAAAAETTTT 2100
TTTTTTVLRR LGTGQAGAEA SVALPASSSG SSSNNNNSPQ SDGSNGNGGG VAGVASNAPP 2160
TGVGVGGNNS SGSSSNSSST STTPAGNGDQ VLEVGIRIKN ISRGRF 2207
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR001478--PDZ
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
PROSITE

PS50106--PDZ
PS50238--RHOGAP
Pfam

PF00595--PDZ
PF00620--RhoGAP
Gene Ontology

GO:0005622--C:intracellular
GO:0005096--F:GTPase activator activity
GO:0007480--P:imaginal disc-derived leg morphogenesis
GO:0043547--P:positive regulation of GTPase activity
GO:0007266--P:Rho protein signal transduction