dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0054112
Uniprot Accession X2JDY8; X2JDY8_DROME;
Genbank Protein ID NP_001285296.1; NP_996441.2; NP_996444.2;
Genbank Nucleotide ID NM_001298367.1; NM_206718.2; NM_206721.2;
Protein Name GRAF ortholog, isoform G
Protein Synonyms/Alias
Gene Name Graf
Gene Synonyms/Alias CG8948;Dmel_CG8948;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
174TIQEADASLGMHEREPHOSIDA21081558
390MDGTEPTYLAPGKIKSysPTM 2.018281928; 19366988
654FLNQQKIYRVVSKTNSysPTM 2.018281928; 19366988
806ANSSNRISLSNVSPPPHOSIDA;PhosphoPep 2.021081558; 19060867
811RISLSNVSPPNTAMRPHOSIDA;PhosphoPep 2.021081558; 19060867
815SNVSPPNTAMRKERFPhosphoPep 2.019060867
825RKERFLGSASGPQQHPhosphoPep 2.019060867
841PVQRGLHSYGQTKHYPHOSIDA;PhosphoPep 2.021081558; 19060867
Sequence
(Fasta)		MGGGKNVRRG LEPLEFEECI VDSPDFRENL NRHEKELDHT SHQIKRIIKE VKDLMSAAKI 60
LSTRMKQLAI LLNDFNFECI GTAQTDDENV ICESLKRFGA IIGNIEDERE KMLTLADKHI 120
IESLEDFRKK QIGGVKENKK KFDKKTEKFC QSQERFLNMS TKKPENTIQE ADASLGMHER 180
EYIQESLSYV LRIQEVQERI KFEFVEILLA FISGWLVFYH TAHEQAEDHR DYLQDLRHKV 240
QKTRENFEEA REKVTELKTK YMEKRTKPEE IFTKRGYLFL MEKSSILKIS LLEPFKATWT 300
KYYCTFKKQK REFTMLQFNQ MNHNFTRPEA RDDEKLTLFS CQRRASEFEK RFCFDLTFKE 360
KPGVVYTFQA LSEKDHRYWI SAMDGTEPTY LAPGKIKVSE AYHLDEAGFM FIRRCIQVLE 420
IRGLEDEGIY RKSGVGTKIS KLLALGLNQK ESDDVFVDDK YRDLMESNTI ASALKMYLRN 480
LNEPLMTYQY HSDFIEAAKQ ETLNQRVNEV HKLVYKLPQP NFQMLDMVIC HLTDVSRKYE 540
KNKMSVFNLG VVFGPTLLRP REESVAAILD IKFNNIVINI LIDNYERIFK NKPSADIKLP 600
DATKAPSIMY PSRSSPPTRM PRASQIGKAA STGAMGSSSN TAGNPMFLNQ QKIYRVVSKT 660
NCTEPTMSSS LQNIPNGDNY ALGSNAMNSS GGAQCISLSP PMHMLNGILS PTIGSINNLH 720
TISKNETSTR RYVPDTEIAP DYGIIGANNG GVTLQSHHAV PVSSTSNFRH PEYLMTTANP 780
VTQSGSSSHI YTNTSSAGAN SSNRISLSNV SPPNTAMRKE RFLGSASGPQ QHPPVQRGLH 840
SYGQTKHYSP LMPTSTSSSN DSVCDSLSSN NGLGSSIVAN SGNSGNVAQH LSARNTNDYA 900
LISSQNSSLS PHLGPTCDEV VTATTLPSVS LSCGGTASES TEYPPSKMHR NRDVNQIKRD 960
LSTGTARVRT LYACMGESEG ELSFEPNQII TNVRYSHEPG WLQGTLNGKT GLIPENYVEH 1020
LKPHH 1026
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR027267--AH/BAR-dom
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain
PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3
Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9
Gene Ontology

GO:0005622--C:intracellular
GO:0005096--F:GTPase activator activity
GO:0005543--F:phospholipid binding
GO:0043547--P:positive regulation of GTPase activity
GO:0007266--P:Rho protein signal transduction