dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0054104
Uniprot Accession X2JAM4; X2JAM4_DROME;
Genbank Protein ID NP_001286919.1;
Genbank Nucleotide ID NM_001299990.1;
Protein Name CG45186, isoform AE
Protein Synonyms/Alias
Gene Name CG45186
Gene Synonyms/Alias Dmel_CG45186;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 56 (View all)
PositionPeptidesSourceReferences ( PMIDs )
221PKPPGAHSSEEELIScurated22817900
222KPPGAHSSEEELISLcurated22817900
453PNGIDFHYVADATPRSysPTM 2.018281928; 19366988
588HHYQNRRSGEDLPNKcurated22817900
680SSKMRVPTPSDFEKFcurated22817900
799KKQRAIRTQSANIYNPhosphoPep 2.019060867
801QRAIRTQSANIYNLIPhosphoPep 2.019060867
805RTQSANIYNLIQRDASysPTM 2.018281928; 19366988
835RNLERAGSMSNLQGEcurated22817900
882PIPFRHPSQGGAIAQPhosphoPep 2.019060867
911PVPAPRKSLTPEPMLcurated22817900
913PAPRKSLTPEPMLDDcurated22817900
1703SKELPAVSSSSDEEGPHOSIDA;SysPTM 2.021081558; 18327897; 19366988
1704KELPAVSSSSDEEGSPHOSIDA;SysPTM 2.021081558; 18327897; 19366988
1705ELPAVSSSSDEEGSLPHOSIDA;SysPTM 2.021081558; 18327897; 19366988
1706LPAVSSSSDEEGSLRPHOSIDA;SysPTM 2.021081558; 18327897; 19366988
1802PLSAIRNSLDDHDLDSysPTM 2.018327897; 19366988
1906RQSSAGHSPPPPLHRPhosphoPep 2.019060867
2187EQRNRYSSPVSPKASSysPTM 2.018327897; 19366988
2190NRYSSPVSPKASSNGSysPTM 2.018327897; 19366988
Sequence
(Fasta)
MYLIQTVQTT WRPQLPLPRE LQLTNDRNSA DDHHDSKVIT TTTTTADIHH HNQQEENEEE 60
DMDRLRGNHS IGGSSQQLSG KQKWSFGRLF RKKKEAESAS SSEEDRKAGF VPAQRQSASK 120
PKGKHGKGSR GCSKFDHIVV SQRQEQAPPH PPQPQIDNEF FLPLEAIQPE PYYQNQPGYY 180
QRSSNSLDRR LLMQPGVQGN GYQQPKSRSA QRGPKPPGAH SSEEELISLN SSTFSKYRSD 240
ESIHLGSAAG QSRRSRAARN ERYYKRLSRD GEPSHGGAPV VAQQRYKTQP LPLSIYQPTN 300
ASTGYVQWQP QPQKNLQNAM QNDGKRSISY DSQIHLQNMN GRMQSKPLPP PPPPRDPLRR 360
VHVGGSGKIG SSSGDLRPVS YAFDHNSRCA SDDRIWQPPH YQSVHSLNSQ PSSSIVSAPV 420
SQQQPHHRRF ITRSERNANP GKQSLPNGID FHYVADATPR SRKPIHMMDA GRMDNTGVPA 480
SSGILRTSKS GLPTPSPAPQ QPLAKPRSFS SSRLSELRTY PMPMYSEVQK PKRNAPPVNP 540
SPNQDNIVCG SLHIKPTQEH GNQNYVEIRH RDVHKTNSMP HHYQNRRSGE DLPNKYEEYV 600
AEKREQHQQA PPPVYPERKM SLTPAVAPPP PVYFPRKKPA NLEEAINELE AIYKSLGLTE 660
PAEPKQEPKL DISSKMRVPT PSDFEKFALA HADDYEDEDS PTGEPDPIRD DVAFRNLQLA 720
NLQHRPSEKQ PPFGIPVGPI VPAPQSDYLH VEPVRVKKKS GSPDIIKDDL AVRSLRKDPP 780
GPKSSFVYPM QKKQRAIRTQ SANIYNLIQR DAAKPSGGDL KSYMELTRNL ERAGSMSNLQ 840
GEDGSDTKDV PATLDLLRKL KAQDEELDLA RKHHPIPFRH PSQGGAIAQL PERLSKEEIP 900
KAAPVPAPRK SLTPEPMLDD ALNKIAQDAQ ASSIKLSQEL HELRKEALIT AARPKLNAEQ 960
QRLEDELQQI EAVSEAAKRC GQMLLETLPD AGQEGQEPQD KPLRKLHKEG KLIRAIDEVS 1020
EAANAVCEKI LKDIVTTEPP VVVQEALQVR QTTKTGPGGE QLVMPHLIKK LDPIQSDKIE 1080
HIARRCMRQL SELANNPDYD NLATCNMSNS TTNATGGAAA DATLVCPVPE TQAKSQTLEE 1140
IDKIMQECER QAKSSSSTTT TDDQRTTAPS LTSGSGSGSF PPNVSTTASS FSSSSDCLAK 1200
SSSPSRASRP LSSSITSFNP YSSSDYIKSQ SSDCHAPSTD PIKTFSTTSY EVQSTPQSTT 1260
ISTNTMSTSQ SNTISSTTNP SVESKPSAPS VSPPPLQLTP VGDRRGRNRE RGASCSSTSS 1320
PSQYNSSEEL AAIFGIEEQP KQQRRSRQTH NATETIAASS DLSTAPATAK TSCQPPEPLK 1380
QKPPQQQTTK DSEDSSSQKS APVQSYRGQH PHFHHHTTPA YYTDLQLRIH TPNASDVGAL 1440
NENYRSVYST PSTQLVEQRS FPKSSTATKD PPLPISNPAR GTFFRGDSAS SDSHSRLRRS 1500
QQRTGSEGRF FRYSQGSVSP TKGEPPIGHE GGEQPPVVAS HSPITSTSTT TISSCNPVEQ 1560
ASPPPTNVVN PSGSGRNSRH KQRFHSRSRR AVRVRSESRP ISALYDIICK EKNLENSSSS 1620
SSSSNEQEKK KDQEQPKTTT DKLATFWPLH HHYLNPPMSS GNSGGSSGNP KQQQQQQQQQ 1680
QLEQLGHQTH LVLGASKELP AVSSSSDEEG SLRTLHSSRK VTNLNAKSTS LPPEEGLSGD 1740
VSLESSSNRL NLRLARSLEP SVRNITASAS KEVQSYDAGE PVNTNRLFVE PPKIPLSAIR 1800
NSLDDHDLDI EECDSTTQFD QGDIYDTLER WSHGVSLGAH LLNCANGHDQ SDPEDDHQTD 1860
HHQHAHQSLP VEPKSHHHQH HQATNARRFI TRTTRSASRQ SSAGHSPPPP LHRSDDSSSS 1920
SPSPTRRRNK PGGAPAATDP PSSSANGNSS AYETAATTVM THDQQRDPPV EVPKALNVEP 1980
PQPEDIVLGS CPTASAHSAE SQSRGKAGKC SINCTYSHSH STNNNCNARQ RNSSNISSNN 2040
TISSNSSSSK STCNNNSKQQ HATPMPPLAN ANKAPLIVLK TAASAAALPS IAAAATSSGT 2100
AATSGGVGSP IKRRKNPLSP LLLGSQCQST IAPPQAIASP LLSGGSCSSS TTSPQSSPAV 2160
RTTKASRLRA AALDKKKEEE QRNRYSSPVS PKASSNGGVQ AQRRLSNSEL SPKSPGASGF 2220
TSEPVASATA NRVPTRSASH PVDTPPTQRR QPLVAVSSGI SMKQSLSELH FTGGAVSPPK 2280
ATAECTLRMR PRSSTMSTEN TENGRRDHLA NLQLSPVQKQ KRTPEVSPRR FGDRDKSAKR 2340
KSNLNRSLTE EATKDGDEVA SSTRRRRRRE LGMARPLVPG DDDALRDLLT PQKSSCSEST 2400
NSISEPHLQF IPAVRHPVVP VRTMTAVLPA PRPLHTPAAR NVSQKFNERT KTDLAEIKKI 2460
AEQSEAQVQQ PSVDDNQKMS AIMRRKSTDE GGSALGATNQ NSPPAPNQIV SILKKKEHGL 2520
GECNSSASSN PSPVTFSSSV VDHPLAGAGR CKRQGILKKR SSLDESRYYS RSHSPDERSI 2580
LIKSARRNSL EEAGTGLSPA QAHGILKQSS YDSSKSDGCP SATESQPHSI LKKKDSLSTP 2640
SDGGCHKHVS ISQAVTLAAA ELAAHDGITF DDGEEHEIRP ILKQESTSSE EAVRPPKPIL 2700
KKKSFGEADE HEIRPILKSS RKSSREEFDL SGLENEVNDS LSSILKTDSP SKRRSLGSAL 2760
HDLEESTTSP SMLKRRTRSL ERQDVQPGMD LAAALDAIAT SQATPSTPVD FVTTPTSISV 2820
AERIKRMEML STPTSRAAGG ANSSWESPLQ ASSAEHGAPT TPRVLKPSVL RRDLQRERYK 2880
TQPVTNEEMS FFKANSAPFD ISATSAFKPT KPLDIRLTHA PHAPLISPIT GQPLSHVPAP 2940
LLLSSSTNSG AGSSFRLARS STQPLQSPRV VHLAGQATGG SALARQNSVN DSINLSEQLT 3000
LSIGTDSEHI FEMSALEEDS AIQSLSDETA ASASANSTST TTATTMTPPS GLTRSNSVRA 3060
RANMFQQLQE QSRNQRATGT TNSRQSPPAS SAEVSSSAAD NSMHSDERST PNATIDAEFG 3120
KPSTEPLKSI LKTGMPVMGM GRGLMPVDLN AELKNRLKRS THATVSNLRK SATSADATRA 3180
ASDEVDNPQR NLAQILRNVS KENSTPKHDD AVSLVRNLST LGQPRSLARD DAAGNCASAS 3240
EGESSGGREI EAIIKNSAVA RRRRQQQQQS QQQNQPDGNL VAKSKSHSGI SAPIGLGPQL 3300
PPLPLGGGFV KLRHVAKEED TSSSSNTSSA KESPDKKDLR QEQAEASGDS SHPTALPQFL 3360
QGVQRSSTEV MGPDQRSLVI SKTGSIAERL AALHKSGEDD WKKRISKRDE VDDVHRENFV 3420
NESLSLAHSL SDKPLPPSPL IPTSLEGGKV SDRLSKLKCN SENWKQRIEQ TDAKKFTVAG 3480
RLQKKAQSPV ELQFERSAND AAKKCPMLEV RSANQPQLGL AKSPSMMVTS STSTNSTSKS 3540
ALRSLSVNPE EEGPTSLSRS NSSSSESDGE RKSPQNAKQN KELANNKSAA APTNVGARIQ 3600
VPRLDDKETF ENFFSSKPKK EENVQLEISA FDDIKPTERL VSKRHVQGPK GRRAARNPLK 3660
SLAAREDISS EYTEMRSGIA ERELRRLKLE SYGHNANLAA EAIAGLASVE DFKSVALRSS 3720
SIPLQQMWLP HKPVMLLHVK GRTHVQTRLV EPVHTSLNRG DCFILVAGSQ LFRYVGSFAN 3780
VIEISRSKKI CAAIVENKDL GCTATQEVIL TDGKYLKERQ WRQFWQLLGK KEDDQSDIAE 3840
CGHADEDDVF ESSLIETNKI YEYQDEALIP LEKFWGCIPK VDMLDTRKVL VFDFGSELYV 3900
WNGKNAPSDA KRAAMRLAQE HFGAENSADY ADCYLNPLNY VAIVGRRENT KYAKRCAQRP 3960
EWCVLGKITQ NMETVLFKEK FSDWPEIERE DLEKDYLSNG VHMVRALNGT ALHKGEPYQE 4020
PNLVLEQANL GRGNFYYDTD TMRHFDVITK STDKWQIHEF NFDAANNRDD YGHFYSAESY 4080
IVRWIYQISV TVRELSGKVS NRSTVGRDRC VYFTWQGQDS SANEKGAAAL LTVELDKEKG 4140
AQMRVSQGDE CTAFVRLFRQ MWQHRGRKEQ CLERHSEWRL YQLQGNVSEE TIIKEVVCQS 4200
SHLRSRSSML LIHGSQGNVI VWHGSKSAPH TRNVAVGVAQ DLIKTVPKDL FSAETANLTE 4260
VEEGSDDDQC KKALGLKDER NEYGSLLKST KSFDYQIRIF NFSSTQGVFK ALELSDPLRC 4320
QDLHSPYPFS QSQLYNARQP TIFLLDDGDE LWLWMGWWPL EDVKINTDER SSPTNENRAG 4380
VNRWISERRA ALETAVDYWR AKHGENENEP FHGIKGQVVW AGLEPLAFKA LFPDWTERPD 4440
VREINEEDGR TDASISIATM LAQMTQTEYP LEVLKARPLP EGVEPTRLEV YLNAEDFQAA 4500
LGCSRAEFEQ LPIWKQTKLK KERGLF 4527
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR029006--ADF-H/Gelsolin-like_dom
IPR015628--SV/p205
IPR007122--Villin/Gelsolin
IPR003128--Villin_headpiece

PROSITE

PS51089--HP

Pfam

PF02209--VHP

Gene Ontology

GO:0003779--F:actin binding
GO:0007010--P:cytoskeleton organization