dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0054101
Uniprot Accession X2JA38; X2JA38_DROME;
Genbank Protein ID NP_001286002.1;
Genbank Nucleotide ID NM_001299073.1;
Protein Name Tweek, isoform J
Protein Synonyms/Alias
Gene Name tweek
Gene Synonyms/Alias CG42555;Dmel_CG42555;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
806EKELANKSISETQPPSysPTM 2.018327897; 19366988
808ELANKSISETQPPEESysPTM 2.018327897; 19366988
3940LDWRGDITPSEIDVDSysPTM 2.018327897; 19366988
4020KSHKREKSIGNDWGSSysPTM 2.018327897; 19366988
4027SIGNDWGSPTPSRRQSysPTM 2.018327897; 19366988
Sequence
(Fasta)
MEALEVEDTS DDSLPMGFPE VGTWNSTHNV SLNDMNLDAR MIWLLASLLT TITWVTYITF 60
YNSRVIGMLI TKIANRWFIK GAYFKIGSVA LNPLAGKIMF RDFVYITYDY TVRAQDGYFI 120
FRWWRSYVPK DVSEDLSHSD TRLSVQLNGY ELHIYNRSDL YDTLEKTFGL EPSLLIPTDA 180
ASNEERNKLK EHHMNLENAR QSQRIQNVKN SEAMQATTWR DLIPVIKIDV CSGRFVFGNR 240
LTPTTLSISV EEAHCTYSTK PAVCRLDHFM HFVKAKVENA KVLFCPSPKY TGLIDEPPRY 300
MGEGFVVMMS NQMDLYFYMD EPGVVPEHPV QIVLPNGDVV EPSPPVWGIN ARCLRGTDFS 360
YGPWADRQRD HLYRYFYPSD WKEAEVTPTP QPGELRSYQS FDVTLCVLNE ATIDILFSKE 420
KETNAMHITV GPASYVEMTI PWVTQPDGYT SKIQGQLFHV EATTSLQYRS LAEFESLEYK 480
VRIHYPTKWN APQDWSISLS GCKTSAFIVY KHKCFFQDLI EDWANKARPD ILSFVPYTCN 540
FSIRLHEFEI LMLCNEYNWI DCSSANQENN HLAFCGDVFE MSFALPFDDF LPKTVTLKFW 600
IHGEGLDLSL YVPEVSSVRP IVLAIDENAR LLTREGKLIR RPELYSKKWR KICQRSAGWI 660
DCWAVPILAL SIQYVYHPVP PLGPDPQADI TTPEKEEILL SPMRIPKVRK SPVSSWQQPP 720
EQYSKFDPGT LAADHVTVEL EIGSSVLMAY GNVLRNFISL KENIFGEDQN FTDMEQSNVN 780
MKEPGVAQVN PKDQLLAKEK ELANKSISET QPPEEKRKPF DPRLYRPLEV MVSVIVHDIQ 840
AHVMKNCNED DPPCPVVLIE RFGFEMNKKY HETTLQVLVS PSYLLTSDCL QRSQREQHIN 900
QGHLMLSAVQ VRGHAMFSNE GCALDEDTLE YSWLVEVQLG KLTGKLTLPQ LVNVVTGLET 960
LILLAIDPEN CLKSPKTVRN CHHGVPSNLC PQTKEEKKYK CPSSEDIKYK MTRVSVDAVD 1020
VYLIESGTAL HAWISPIRLA NCNLHGQRVK SGISGLLPSI LLRLFMLHTT NSTFNTNTTG 1080
SNRSGKLRRA DQDSLKSQDA GGSHYASHGK TGKRSSNSFS RRDSREEATR KLRGSFSETH 1140
TKRTPETEIT ENWVEVGCTS LGPILLEGAS ALPIPDHELH LVQHNFLREH DAKFKRLWFL 1200
WSNNGSALSS GSEISRCGCI GGCAFFGSNR NGQKFFKPTA QDAHDNYNIA RYFIINNNKD 1260
FGFGESILHQ GQLVFHTPPY SLHCVSLYDT ADFNGKGRLY RPAGDLRNGS LKKTDLCSLP 1320
DGTKFKIGAS GTTGVEKPEP NCRNKSRESI GSPNTLERRT KRYPCTRQTS VDVPYARLLD 1380
SPSKKLQLQH EASAGDAGSS HRRGSDSNRL RVSPPKTSIS DSRLTGDVLD DETEIPDEMS 1440
HSAPHSHPLE FEIADIALHV QGLGGDQLPR EVQRTISLTS ENPSEMFFSA EEDISNVLSQ 1500
RGSMKQRNSV NSGSVVLSGK KRFSSDLSIG AQNDNGSHTL PTYRSDLEIH APDGNKTLPK 1560
RPQSTTELNE DARRIHGLAT PIRKITNISS RPEYRHFVHD ADSRGSSSGT PSLSSNSFIS 1620
AMSSQEDVAL VNLHQQVNRP IIDSPLLMAS YLNHLSQVKC FNWNGCSFPL GPDVFSTPLF 1680
SENEDGGLTY IGSKMLPHFD LYSCWREIKV VPRYENATGS NSSATFMGGP KSHPWDPSVL 1740
LKEEESDKTT NGFDDGEFMS LQAEGGAVCT SVVARLKGQL NVFLTPLLLE GLQRMVEAAV 1800
PTIQSMHLLS VVNFIHTSCI AKVNNDNILK RDQSLSYWSQ VHSNSKRSTT ERHLQGPGDS 1860
FLSDVYEESI STKTQGLIVL PKVSITMLQS SIVEEIISVA ALDNVQDLSC VSLLTFYMEG 1920
ISTKFHMGKT TRASMHNVYI QQTVQSGSSN KKGGIMKGTR ALLAHLSSQT RPDNVQGEPI 1980
LIETSEKQLE EVVITLDIGR AHAQLRRLKT EGQSCTQDSP IIVTAIPEHK SKVLFECLKM 2040
PESTGIESIG YIMFECGLEG VGVKIVKRSH FEKSENSKEE LAEMAGAGAG GGASAGGFNL 2100
NDLVGQGEGA AGSGDGGATS KAEAAWRLIT KKPPTPKTPK EKFQPASDSN ISAETSGAEK 2160
GKSTPKPPDE DVEKGTSPAN AQTGAQKPSA GAGTNTKDNY DKVLSNVKET DKTSSCVIEL 2220
KAVWFNFAAP PCVPITRKID LTRLDWNLLS TASPAITAWM NPSNRLAMKI VSLMKALHTR 2280
QTAVAACLMA EAMDNEKIQR NPKIKKSRYA NNYTLLSKTL QEDPSCQLCY IMQKLVLDEG 2340
VQRIETIFKQ HDVPHLNTLR QGIIVLSRQW KNTLYNPILF EHQYKNKLSR PINVTFSFPQ 2400
NEEDAENDEC EGDVEMGAFA GVGENPEESE NALLLGQTQH HRTHIGATYG HEGANHGTAS 2460
QRSTSTSPNI HHPRRGLNKV HSKASNYSHG NSSRSSIQML PIISGQVPEF EYGALQEGSL 2520
SSTNSVNKSW LGTENHKEDL YFWMAKQQDN KKKHFTEKEH ARPAPPKMTE HAGQTRSGIM 2580
QDSIKLLDAH LIFEPLLTCL GVMPQQMINK FSNADISSLE NFGTNLSLIG TFDSIRVDIV 2640
VSEAGDKKNS AQKPAKLNKK SNGGRASIMM DTPLFLCERV GVELEVLKMS DGMVDQARQN 2700
VIYMSRRQLK KHTSTVINFS LNVRFISQQV NMPLLRLLHQ ICNMYQNVKD AQNEFHDQPE 2760
LSKKSQTKDE CSLASEPTDI VPFNSMSERY NHAENYSDER YDKFNETMPT MLARPRPGGL 2820
APIIQLTPSP NAKNRPQSFA QKLRSTGKSV KGKLGYTNLN ESSSSPLRDS PTMSLHEHNI 2880
LKMSTESKAS LNGACATSVS GDYQNTLTKA GMPTMAPMLE TPNCWKTIYH LLELYGTMPE 2940
TKTVVQRSSL NEHKSKSAGF AHDDDDLASA PTPLPQHREM LLVDASSQER TRLIVFGVAK 3000
IHKTRLLATL SGLKLESEIT TLNSTATWRK KARPVSLECS LTGQVGRAMI VLLEGVAPSQ 3060
QTVVKVTVGK SQTLYSSLSK RGKDKNSGLL SIGAVNIDIP QHPVALHGMM TRSSKQLSST 3120
LQELRVKRNS GRSTMRSHTA EEPESPFHAR NSVGASSGTG VASEMRERTV SGGAGAQQQP 3180
QQAARRAAHM AQSKTGTAQH QNGLLQPLVM QFNVLLQSLS INAALLPSLQ AQYRMNHVSS 3240
MGVTGQRAKF VIDLPTHTLS FNTKIQNEMN LPSEACIGLP PVHVLAEYIP DHRQDHTENV 3300
EGIVLRQGGY VNASAEIGEF ERCLTTDLLN HLVFVQKVFM REINEVLQKV YGGEKPVPLW 3360
TEESGDSSGA VQESSLKRIL FSINISMKRI QLTATTPCSS AVRFETGILE LQLSNRVKNL 3420
GDMSNRKLFF KAHIDFNLSL GQIIRNVIFD EAEPEFQQYA FFHTTINLRN AFQDELLNED 3480
KELILLTLKR PLVYVQPIAV DKAILVWLNY KNAYEYWAEK RANLCHEHAQ HSLLSQYSGQ 3540
HQNQNMQNPQ VFDRVAFGQI AGSNLSTLFL QLTVEDMGIC LPLKQVNTTT FGSRSYQDFD 3600
AKGAVVITLE NTIISACNSG ALVSKGKFQG LCLRFADDFE TNLDDWKPNS AEPIMNVCVV 3660
SEGTFEVCSR TTAAKKGENA KWLLNVKWQM EGVDIHLDVN IGKQLSSLGH TLTMLTGFEE 3720
DETQMESPDS DEGDQSCRDT FVRRRGDFDN LPAFVFDPTI DSKKRSFMME KEMAEQLKII 3780
NDLRTLGASH NTVAHEERRL QELQAICYKY FRRDMIQKWK RPSLRRSLKT YGRSHSYIGS 3840
GSSVSGVGVP QTLDNVSYTG RRLDTIASND EISSLQSTPA SCHSRSASLK HTTGGGVIGG 3900
GVNALGRVTF TEAMRQTSLP NADTDTETAD NELDWRGDIT PSEIDVDGTS VEMRRKHGHG 3960
QKQPEPNIDF ELDIKVLVNS GKCVLHTKDT GEERGYAGGS GAATSGVPAS SVKSHKREKS 4020
IGNDWGSPTP SRRQRDKSKL RYNANALLAD LTIFHIPGLD VKLHYQSKTL AEQLTGDQLP 4080
TGRRMGSKRA TLCAWMTLQS IPEETIISPH ILEFLEQTLE PIPARQSSSV PPTPSHNTGV 4140
NLDILPANYV TYASFPVDVI VYFHMQPSTF RFSCLPVSRV ECMLQLPSLD IVFSSKRSSE 4200
EENSAQPGGH TQPDQQLPTG GLSVTGCLAD FNVFIFHPYG GKKTSKETQF SPLSDSERKD 4260
SLSINVEFVK FHITRCRKVY IEPLPSSKRS LDQSRAVIRF STIVDIGSAS FKYDMRRLTE 4320
ILAFPKAWYR RRIVRRLFLG DLSVQQQQQQ QQGNGAETPT GCPPATPTPN EDASRAKDNM 4380
RLDFDGQPSQ QQQQLGHFGA VRHLKNLGKS SSAESSGTPP SEKNQITAWE TLVIFAVNFT 4440
KLNVQMNIGN VCGNVVWLTK DFQSDGRLSI GSTGYKNMYA GIYLGGSALD AKGGIVGGSF 4500
EVNKINKRFH IKEEAGMEPY HTMGLSFMAL ELRLDYMGTS VLMTRISSFS AAMKDEWRTA 4560
SQAAATPAHG KDQPRALIFI HGDLTWDQLQ IMISKSTTAD LLKMYFKLEE FFTQQFKSSK 4620
RVFSNLEPRL QDRTASIKRR QQHKKKPANG ELVAPPQIHG MIGENTDARH HRHWQKPLAQ 4680
AVGLVVPSLV TRLPRHGNVL GGTVELRGQN ISLACFHGIN FKSKSWALFS LRSPSINFAT 4740
EARQSEDEVL VTQTLTSSLG QTTEVQQQQN HSMAIVSRIT RNIIFPPQFK TLNEWFHYAF 4800
ANSEIDAVDR FPMLECEREI ASNSIERTRA SGSSSAAKAQ EHNHNREVIF ALPSLQLHFK 4860
TEHKQGPTTP EPSVLCSIAE NKPEVLCSFI TEFDDHIFVT VDADAFFFLH DLITSYVTEK 4920
EKVIGAQSAR AASPNLSQKA NLKPYLTDEI LKEKKGASNT NLTAQGKQTS GSKNSLDPLQ 4980
GSHTSLANAA ANMSGAATTN TTTTTTATTL SPGAAAGGPS TSATNDSVDG KQQQQEGSPP 5040
TFDLESFVRD WRHFECQTWH LEPTVRLLSW AGKSIEPYGV DYILNKLGFS HARTTIPKWL 5100
QRGFMDPLDK VQALMMLQLL LMVRENKVER DSGASGSGKQ QQQNHRPPTN 5151
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR018863--Fragile_site-assoc_C

PROSITE
Pfam

PF10479--FSA_C

Gene Ontology

GO:0005623--C:cell
GO:0016021--C:integral component of membrane
GO:0048488--P:synaptic vesicle endocytosis