dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0054042
Uniprot Accession S6FWN4; S6FWN4_CAEEL;
Genbank Protein ID NP_001293846.1;
Genbank Nucleotide ID NM_001306917.1;
Protein Name K+/Cl-Cotransporter
Protein Synonyms/Alias
Gene Name kcc-1
Gene Synonyms/Alias CELE_R13A1.2;R13A1.2;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
175GPLERAQSSSHGGHGcurated18806794
993SKNAFERTLLMEERTPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
1028ANAPRAPSPLVTSERPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
1039TSERRANSKDSDEGTPhosphoPep 2.019060867
1042RRANSKDSDEGTPTEPhosphoPep 2.019060867
Sequence
(Fasta)
MGDDSSQDKA SAPPSAAAAG AAPAGNPQQQ PASAIRNKVD VPPGFGRRVS SVEVVKNAMP 60
PTKKASVVIF ETPDTPKAER RASSWWRNLV MDDDKTAPVQ SDTVISPENA GNGLADHHRN 120
ISTASVGDRE LYAWGTNKDA GGNHNLALFE EPSMPFFSSY LKAHITPGPL ERAQSSSHGG 180
HGAKADLGVL LGVYLPTIQH ILGVTMFIRL FWLVGIAGLG QTFLLLFLCC FCTFLTCISI 240
SAVATNGVVE SGGAYFMISR NLGPEFGSAV GILFYLANTV ATSMYLVGGV EILLLYIFPG 300
LTFGGVEGQH DTSMFGTMTN SLRFYSTILL LIEFAIVAMG VKFVQMLAPV SLVCVILSIL 360
ACYAGGVTKT IYPDSGQYVC MYNDRLLQSS AVLNESIPLD EICNYCNINN TFLADRVCGG 420
RCNSTTIPHV SPFRCINGFP GFQGGQTLLE NLGPNYLEKG EAAHGTQADT KSDVYQDVRT 480
SFFVLLAIYF PAVTGIFTGA NMSGDLKNPQ ASIPAGTIAA NLTTSFVYFS LAFIFGGAID 540
NAVLRDKNGQ SVGGQMVVAL LSWPSPWVLL IGSFLSTFGA ALQCLCSAPR LLQAIAKDEV 600
IPLLSPFKKV TANNEPFLGL ILTTIIAEIA ILMGSMDTIA AVVDFFFLMC YAFVNIICTL 660
HSLLGAPNWR PRFKYYHWFL SLLGAVLCFF IMFSTHWDYA IVACLLCLVI YKYVEWKGAK 720
KEWGDGIRGL ALTTAQYSLM KIEDKEPHPK NWRPQLLLLL SMQWSKEIID VRYLNLLNLA 780
SQLKAGKGLT VVTAFLQGDP TSPDDKKKGE QVKARMDFDM NQVRLRGFAK TLVHSEDQVR 840
GSMSTLVQSV GLGGLKPNTM LISWPVHERE EDMTEYNTFI EKVHAASIND MAIVVAKGII 900
DFPSAVFRMS GMIDVYWIVH DGGLCLLMGY LLKQHKVWRG CKLRVIGIAQ ESDNNVKMQE 960
DLQKYVYQLR IDAKIMIVEL ADPEISKNAF ERTLLMEERT MMMRDLQKVS GGGMSLSLPP 1020
ANAPRAPSPL VTSERRANSK DSDEGTPTES EETTEKKSTS TDNEQANQET KTKKERMKAL 1080
DRSKVSKMHT AVRLNELLLQ HSANSQLILL NLPKPPVHKD QQALDDYVHY LEVMTDKLNR 1140
VIFVRGTGKE VITESS 1157
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR004841--AA-permease/SLC12A_dom
IPR018491--SLC12_C

PROSITE
Pfam

PF00324--AA_permease
PF03522--SLC12

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0022820--F:potassium ion symporter activity
GO:0015379--F:potassium:chloride symporter activity
GO:0006884--P:cell volume homeostasis
GO:0055064--P:chloride ion homeostasis
GO:1902476--P:chloride transmembrane transport
GO:0006821--P:chloride transport
GO:0055075--P:potassium ion homeostasis
GO:0010107--P:potassium ion import
GO:0006813--P:potassium ion transport
GO:0007268--P:synaptic transmission