dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0054024
Uniprot Accession S4R1Y1; S4R1Y1_MOUSE;
Genbank Protein ID NP_001074804.2;
Genbank Nucleotide ID NM_001081335.2;
Protein Name Cullin-9
Protein Synonyms/Alias
Gene Name Cul9
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
356LLPTIVTTPRKQGRAPhosphoSitePlus22135298
584LLPKELGSLPSSRRHPhosphoSitePlus;curated22135298; 22817900; 21183079
588ELGSLPSSRRHSCSPPhosphoSitePlus;curated22135298; 21183079
592LPSSRRHSCSPEPEEPHOSIDA;PhosphoSitePlus21081558; 22135298
594SSRRHSCSPEPEEGSPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 22817900; 21183079
654LLVTEGMTLPPETQEPhosphoSitePlus22135298
659GMTLPPETQEAATEMPhosphoSitePlus22135298
Sequence
(Fasta)
MVGERRAGNL LVPLGPRLQA YPEELLRQRP GHDGHPEYLI RWSVLKCSEE GKVSSEEEKT 60
EHLLMWLSAP EVYANCPMLL RERPIPKGPQ HEPAGEVGSF PRDPGGLDEL AMTEMEADVR 120
ALVRRAARQL AEGGTSSLTA AVLHTVHVLS AYASIGPLTG VFRETGALDL LMHMLCNPEP 180
QIRRSAGKML QALAAHDAGS RAHVLLSLSQ HDGIEQHMDF DSRYTLLELF AETTSTEEHC 240
MALEGIHLPQ IPGKLLFSLV KRYLCVTSLL DQLNNSPESG AGDQSSPCLT KEKSRAQQEL 300
EFSMAVGNLI SELVRSMGWA RNLSEQGALP PRPSRSIFQP CLSGPPPLLL PTIVTTPRKQ 360
GRAFRGRSEF SSRSGYGEYV QQTVQPGMRV RILDDYEEIS AGDEGEFQQS NNGVPPVQVF 420
WQSTGRTYWV HWHMLEILGP EEATGDSASA AVEKGAGAAV LGTVCPSWDW KPTHGLYSLP 480
YLQPEPQKNE EESGYLTQAE WWELLFFIKK LDVGEQQPIF QNLHEKLDEE ALGEKALGEL 540
SVPIEMAEGV LQVLSNRFEG SNLCDLLNSR IYTKYGLLPK ELGSLPSSRR HSCSPEPEEG 600
SRSAANFSEK EEACRANAVP PEAEMELASA KTEPPKAQSD SQLFNQLLVT EGMTLPPETQ 660
EAATEMARAL RGPGPRSSLD QHVAAVLATV QISSLDTNLQ LSGLCALSQA VEEVTERDHP 720
LVRPDRPLRE KLVKTLVDLL TNQVGEKMVV VMALRLLYLL MTKHEWRPLF AREGGIYAVL 780
ICMQEYKTSV LVQQAGLAAL KMLAIANSSD VPTFIPSRDS IQPLFDTQMT REIFASIDSA 840
TRPGSESLLL SVPAAVVLML NTEGCSSAVR NGLLLLNLLL CNHHTLGDQI ITQELRDTLF 900
RHSGIAPGTE PMPTTRTILT MLLSRYSEPR GSPERAVLET PSTQGQDGSP ESLIRSLVGD 960
LSAELFLDLE RVLCHEGSPP AAVRPLLRRL QQETQPFLLL LRTLDAPGPN RTLLLTILRV 1020
MTRLLDHPET MVLPWHEVLE PCLNCLNGPS SDSEVVQEVT CFLHRLALMQ KDYAVVLCCL 1080
GGKEALSKVL DKHSTQLLLA SELRHLVAEC EKYSQLCSNL TSSILAGCIQ MVLGQIEDHR 1140
RTYKPITIPF FDVFLRHLCQ GSSVEVKEDR CWEKVEVSSN PHRASKLTDR NPKTYWESNG 1200
STGSHSITLH MHRGVLIRQL TLLVASEDSS YMPARVVVFG GDNVGCISTE LNTVNVMPSA 1260
SRVTLLENLT RFWPIIQIRI KRCQQGGIDT RVRGVEVLGP KPTFWPLFRE QLCRRTCLFY 1320
TIRAQAWSRD IAEDRQRLLQ LYPRLNRVLR HEQNFADRFL PDDEAAQALG KTCWEALVSP 1380
LVQNITSPDA GGVSSLGWLL DQYLEHREST RSRQGPAASF ASQVRRLCHL LVHVEAPPGP 1440
SPEPSSQPLS KNSKGQDGSP TPAPTPVCPS TSLRNLTQCW LSVVQGQVSR FLAAAWRASD 1500
FVPRYCSLYQ RLQSAGSELF GPRAAFTLAL RSGFSGALLQ QSFLTAAHIS EQFARHIDQQ 1560
IHGGLLGGAA GVGMLGRLQR HLEPIMVLSG LELATTFEHF YQHYMADRLL SLGSSWLEGA 1620
VLEQIGPCFP NRLPQLMLQS LHTSEELQHR FHLFQLQQLD RQLLEQGDQE EWRPEKVEED 1680
DEGQETGREL FTDPGPAISV LVLSPRCWPV SPLCYLHHPR KHLQAELCDA LERFSSFYSH 1740
SQNCPVLDIG PHRRLQWTWL GRAELQFGDQ TLHVSTVQMW LLLNFNQSEE VSVETLLRNS 1800
DLSPELLHQA LLPLTSDNGP LTLEETQDYP QGGVLRLREP RSQTHEEVLW LIPPQTYLSV 1860
EKDEGRTLEQ KRNLLSCLLV RILKAHREKG LHIDQLVCLV LEAWQKGPDP PGRLGNAAAV 1920
GVACSSTDVL SCILHLLGQG YVERRDDRPQ VLMYATPEPM GPCRGQADVP FCGNKNTETS 1980
RPSPEAVVAL ASLQLPAGRT MSPQEVEGLM EQTVRQVQET LNLEPDVAQH LLAHSHWGTE 2040
QLLQSYSDDP EPLLLAAGLR VPQAQVVPTR PDQCPVCVTP LGPHDDSPSL CCLHCCCKSC 2100
WNEYLTTRIE QNFVLNCTCP IADCPAQPTG AFIRNIVSSP EVISKYEKAL LRGYVESCSN 2160
LTWCTNPQGC DRILCRQGLG SGTTCSKCGW ASCFSCSFPE AHYPASCGHM SQWVDDGGYY 2220
DGMSVEAQSK HLAKLISKRC PSCQAPIEKN EGCLHMTCAR CNHGFCWRCL KSWKPSHKDY 2280
YNCSAMVSKA ARQEKRFQDY NERCTFHHQA REFAVNLRNQ ASAIQEVPPP KSFTFLQDAC 2340
RALEQARKVL AYACVYSFYS QDTEYMDVVE QQTENLELHT NALQILLEET LLRCRDLASS 2400
LRFLRADCLS TGTELLRRIQ ERLLAILQHS TQDFRVGLQS PSVETREVKG SNVPSDQPQG 2460
SSGLEVEDEE EEEEEEEEEE EEEEEDVPEW QHEFDEELDN DSFSYDEESE NLDRETFFFG 2520
DEDEDDESYD 2531
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR004939--APC_su10/DOC_dom
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021097--CPH_domain
IPR031222--CUL9
IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR008979--Galactose-bd-like
IPR002867--IBR_dom
IPR014722--Rib_L2_dom2
IPR011991--WHTH_DNA-bd_dom
IPR001841--Znf_RING
IPR017907--Znf_RING_CS

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
PS51284--DOC
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00888--Cullin
PF10557--Cullin_Nedd8
PF01485--IBR

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0008270--F:zinc ion binding
GO:0000226--P:microtubule cytoskeleton organization
GO:0016567--P:protein ubiquitination
GO:0007088--P:regulation of mitotic nuclear division
GO:0006511--P:ubiquitin-dependent protein catabolic process