dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053996
Uniprot Accession M9PI41; M9PI41_DROME;
Genbank Protein ID NP_001261768.1;
Genbank Nucleotide ID NM_001274839.1;
Protein Name Sticky, isoform B
Protein Synonyms/Alias
Gene Name sti
Gene Synonyms/Alias CG10522;Dmel_CG10522;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 12
PositionPeptidesSourceReferences ( PMIDs )
46IPASTRRSIVPVSTTPhosphoPep 2.0;curated19060867; 22817900
265DRDGHVLSLSPVGTPPHOSIDA;curated21081558; 22817900
267DGHVLSLSPVGTPDYPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
673QDTNRRMTMEIKEIRSysPTM 2.0;curated18327897; 19366988; 22817900
832RFNEQSLSPTKSHSSSysPTM 2.0;curated18327897; 19366988; 22817900
836QSLSPTKSHSSRKQESysPTM 2.0;curated18327897; 19366988; 22817900
1331TLRSPRKSAAVNGDSPhosphoPep 2.0;curated19060867; 22817900
1347APKQRPVSIAALPRSPhosphoPep 2.0;SysPTM 2.0;curated19060867; 18327897; 19366988; 22817900
1354SIAALPRSPQKQQQPPHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated21081558; 19060867; 18327897; 19366988; 22817900
1365QQQPLKRTTSQVELKPHOSIDA;curated21081558; 22817900
1367QPLKRTTSQVELKTTcurated22817900
1416EKAVVAGSPFWKCKEPhosphoPep 2.0;curated19060867; 22817900
Sequence
(Fasta)		MPPKMEPISV RTARLNNLIL GKGAGVCAKP AGSASGSGIP ASTRRSIVPV STTSAAVAEA 60
ICREGLLDAF CLLYNECDKD TLKKRDRNIA EFVNKFRPII EETRKLRVNA DDFLIKTLIG 120
QGYFGNVHLV VERQTNDIYA MKKIKKSVVT TSQVKEERDI MSIRNSEWLI NLQYAFQDND 180
NLYLVMEYMP GGDLLSLMSR HGPFDEDLAR FYLAELTVAL HTLHEMGYVH RDIKPENILI 240
DRFGHIKLAD FGNAAALDRD GHVLSLSPVG TPDYIAPELL QTISTYKLSK SMHDVSRIVS 300
CDYWSMGIIG YELICETTPF HEDNVHETYS KILSHCEESH LKELISFPAD LKVSVNYRNL 360
IESLVTNPSK RLSYERIKNH PFFSEIPWGS IRSQVPPIIP TVRSDDDTSN FEDGIRHKTR 420
REQGVAKKSL TTNMKSNDFS GKDLPFIGYS FVHMEKSAIS ATTDEKLQEK LKELLQKLKT 480
RENEISMLKQ DLLRAQQSLR KTDNKSQVVA DAKMEIKKLQ QIIKEKTMEL TTCKTQIKTL 540
QSSAKIDEEM WSKKEATITD LLRLNRQKYE EAKIASEQRY EKQLADKKQE LASTLQKLDA 600
RELEFNAKFE ECKHLSMKLQ NYKDMLQQIK EQNLKSETNH EEQRRQMAEL YEQKLTDLRK 660
KVRDSQDTNR RMTMEIKEIR TELDESISSS KSTQEAKNAT ERNIEEILRR LNEEIASNNE 720
LHAEKVKLET KLQLKENETQ EVRAECHRLE RELQLAECRC QLAESSLATQ VSPYETAPGS 780
LTELNAIEDQ LRADLLAAKE SENHQKGRAD QLQTLVTKLE QMLERFNEQS LSPTKSHSSR 840
KQEGETVGDM LERQNEKLED KLAAVREQMI VERQAARTAN LSLWKVEKQL EEALSEKKLL 900
ARRMELTEDR IKKVQNASDE AQRMLKTSQE ETRQRESRIE ELKQELAAAK RDVLKEHRQW 960
EKAEQERMKC KSEIIEHLAN VHRLEQQETE LRQKLRQIQS RFDGVTLEQK NTIRELQEER 1020
EKSRKANDSC LVLQKELKQL TDNFQRLKYA CSITDSQLTE VETMLKSEQE RNKSQKSQLD 1080
TLHEKLRERN DQLTDLRKQL TTVESEKRLA EQRAQVLASE IDELRLNLKE QQKKLVAQQD 1140
QLVEQTNALF ATQERAELLD GQNANYEAQT ADSNREMVSL KEENARILSE LFHKKEEVGN 1200
LQAEIRGLES AQANLHAEID SLQDTLAEKE QFYVQRDIKS NATLAQHKKL IDYLQLKVED 1260
LSAKKKKTLA DKLFGSSHTN KENVSPNDVE SSILYRALKE ELKREQKMNS LLKEQLAQLN 1320
GTATLRSPRK SAAVNGDSDA PKQRPVSIAA LPRSPQKQQQ PLKRTTSQVE LKTTAEKPTK 1380
VTIENQAHHR FELALQESKV DAVNCVVCEK AVVAGSPFWK CKECKDVTHR KCRSNVQSHC 1440
GSTKPTAPSA DDLSSIQSVS SLTLDSVDVA GGTTSGGEYI GSLVYSSDGA EDQARKEIEV 1500
NCAFEVAEQQ ILLLGCNTGL YAYHLDSQRL VHISGLESVS CMSICKRLAK AIMVGTVGEK 1560
LYQCDYRQLE SRCQSSSSCH KPVLETSAIE LPFANRTPSE KWKLVLISDE AENALDSVAI 1620
AATSTRIVIL KYDLKLHMFK PVRALDTATP VTSIFFTRHS AIVSSDKFYE IDLDNYAAEE 1680
FVDLSDKSME STAKCQPLTA VRISRQEYLL CFAEYGVFVD EFGCRSRPYD LNWVYAPTGF 1740
VYRDPFLFIS HYQSVQIVRL HRSFSKEMAS GDNASENSES PELQRVYLPH YMSTLLANSG 1800
DVNLYAVAID QRPCNGTQKI YHLDTMQAFK QKFNISMETL SSVATSVTLG STVTGNSI 1859
Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000961--AGC-kinase_C
IPR001180--CNH_dom
IPR011009--Kinase-like_dom
IPR002219--PE/DAG-bd
IPR011993--PH/PTB_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS51285--AGC_KINASE_CTER
PS50219--CNH
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50081--ZF_DAG_PE_2
Pfam

PF00780--CNH
PF00069--Pkinase
Gene Ontology

GO:0005826--C:actomyosin contractile ring
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0000915--P:actomyosin contractile ring assembly
GO:0006325--P:chromatin organization
GO:0035556--P:intracellular signal transduction
GO:0007112--P:male meiosis cytokinesis
GO:0000281--P:mitotic cytokinesis
GO:0006468--P:protein phosphorylation
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0032465--P:regulation of cytokinesis
GO:2000431--P:regulation of cytokinesis, actomyosin contractile ring assembly