dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053995
Uniprot Accession M9PI37; M9PI37_DROME;
Genbank Protein ID NP_001261758.1;
Genbank Nucleotide ID NM_001274829.1;
Protein Name Sodium chloride cotransporter 69, isoform E
Protein Synonyms/Alias
Gene Name Ncc69
Gene Synonyms/Alias CG4357;Dmel_CG4357;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 14
PositionPeptidesSourceReferences ( PMIDs )
126VDPQNEESDESNDSQSysPTM 2.0;curated18327897; 19366988; 22817900
129QNEESDESNDSQEERSysPTM 2.0;curated18327897; 19366988; 22817900
132ESDESNDSQEERELLSysPTM 2.0;curated18327897; 19366988; 22817900
143RELLDNEYDTKYGKSPHOSIDA;curated21081558; 22817900
145LLDNEYDTKYGKSFRPHOSIDA21081558
194LVGKNTHSLTRNQDPPHOSIDA;curated21081558; 22817900
855DCSQVLGSQDGWKTVPHOSIDA;curated21081558; 22817900
868TVSDVPRTLQPNESSPHOSIDA;curated21081558; 22817900
874RTLQPNESSGDLQAVPHOSIDA;curated21081558; 22817900
892VRNGLSGSIDSLSRNPHOSIDA;SysPTM 2.0;curated21081558; 18327897; 19366988; 22817900
895GLSGSIDSLSRNVSQPHOSIDA;SysPTM 2.0;curated21081558; 18327897; 19366988; 22817900
967PDPLDAKSANLVSNSSysPTM 2.0;curated18327897; 19366988; 22817900
972AKSANLVSNSLRKSKSysPTM 2.0;curated18327897; 19366988; 22817900
974SANLVSNSLRKSKLKPHOSIDA;SysPTM 2.0;curated21081558; 18327897; 19366988; 22817900
Sequence
(Fasta)		MSDTISFELG SAADRPPNRF QVNPVNGNSR KSQGADGPGS GSGAGAGAGA GAGEDGPHEV 60
YRRLTNAEGE LLEDDTFDAT QMLNQRQPRQ QRQSIKSSFR DKDKPSRFKD LQTTTRFQVD 120
PQNEESDESN DSQEERELLD NEYDTKYGKS FRHFTREALP RLDNYRNMMS IQAAYRPTLD 180
ELHNATLVGK NTHSLTRNQD PESGILNGVL KFGWIKGVLV RCLLNIWGVM LFLRLSWVVG 240
QAGVIEGFVL ILTTTAVTTI TALSMSAIST NGVIKGGGTY YMISRSLGPE FGGSIGLIFS 300
LANAVACAMY VVGFCESMLA MMTTFGWEII DGGVQDVRII GCITILLLLI IVVVGMEWEA 360
KAQIGLLIIL LVAIGDFVIG SFIGPKSDAE MAKGFLGYNA TLFKNNLFAD YRPEKGGIQH 420
DFFSVFAIFF PAATGILAGA NISGDLKDPQ KSIPKGTILA IVITTGTYLI MVLQCGATVA 480
RDATGNLSDV VNGTFAFLDC QPGECNYGLQ NSFQVIELVS AFGPLIYAGC YAATLSSALA 540
SLVSAPKVFQ ALCKDELYPK IVWFAKGYGK NNEPVRGYVL TFIIACAFIL IGELNLIAPL 600
ISNFFLAAYM LINFSTFHAS LAKPVGWRPT FKYYNMWLSL LGAILCVAVM FLISWATALI 660
TFAAVLALYL IVAYRKPDVN WGSTTQAQTY KNALMSVQQL NNVEEHVKNY RPQILVLSGL 720
PNTRPVLVDL AYMLTKNLSL LVCGHVLKGS SSQKYRTYLQ ERAGNWFRKH RVKGFYALVD 780
GEDFESGTRA LMQATGIGKL KPNIILMGYK TDWQTCDHKE LDQYFNVMHK ALDMYLSVAI 840
LRVPQGLDCS QVLGSQDGWK TVSDVPRTLQ PNESSGDLQA VDSSVRNGLS GSIDSLSRNV 900
SQEDRNRNQL VHSEQNSLKI VKLRFKQGLR RMRSWPGAAS STSDLSFIAG NQSKDVSGMP 960
DPLDAKSANL VSNSLRKSKL KHDDPASLYK GPGGAELPKE VLADLTQFTR KRSHAVIDVW 1020
WLYDDGGLTL LLPYIISTRR TWQSCKLRVY ALANKNSELE FEQRSMASLL SKFRIDYSDL 1080
TLIPDITKKP QETSTQFFNE LIKDFVVTEK DGENGTSSRA TLNEDDALIT DDDLLAVQDK 1140
TNRYLRLREY LREQSTKSDL VVMTLPMPRK NIVSAPLYMA WLESLSRDMP PFLFVRGNQT 1200
SVLTFYS 1208
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR004841--AA-permease/SLC12A_dom
IPR002443--Na/K/Cl_cotranspt
IPR018491--SLC12_C
IPR004842--SLC12A_fam
PROSITE
Pfam

PF00324--AA_permease
PF03522--SLC12
Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0015171--F:amino acid transmembrane transporter activity
GO:0008511--F:sodium:potassium:chloride symporter activity
GO:0003333--P:amino acid transmembrane transport
GO:1902476--P:chloride transmembrane transport
GO:0006821--P:chloride transport
GO:0006813--P:potassium ion transport
GO:0035826--P:rubidium ion transport