dbPAF - database of Phospho-sites in Animals and Fungi

Protein
Gene
PTMs
Sequence
Keyword
GO
TOP

dbPAF Protein Information

Tag

Content

dbPAF ID

dbPAF-0053990

Uniprot Accession

M9PHT1; M9PHT1_DROME;

Genbank Protein ID

NP_001261581.1;

Genbank Nucleotide ID

NM_001274652.1;

Protein Name

Grunge, isoform J

Protein Synonyms/Alias

Gene Name

Gug

Gene Synonyms/Alias

CG6964;Dmel_CG6964;

Organism

Drosophila melanogaster(Fruit fly)

NCBI Taxa ID

7227

Functional Description
(View all)

Phosphorylation Sites

dbPAF PTMs: 19

Position	Peptides	Source	References ( PMIDs )
244	AVSKEENSSLTEDDA	curated	22817900
245	VSKEENSSLTEDDAS	curated	22817900
247	KEENSSLTEDDASEC	SysPTM 2.0;curated	18327897; 19366988; 22817900
252	SLTEDDASECDSDSS	SysPTM 2.0;curated	18327897; 19366988; 22817900
256	DDASECDSDSSLTHK	SysPTM 2.0;curated	18327897; 19366988; 22817900
335	GKRPKRGSETPDVSG	curated	22817900
348	SGGASVDSPKTPTKA	curated	22817900
351	ASVDSPKTPTKAVAE	curated	22817900
353	VDSPKTPTKAVAESS	PhosphoPep 2.0	19060867
402	EKRKRPDSPVESMNS	curated	22817900
406	RPDSPVESMNSDSRP	curated	22817900
607	KKEPMEDSMDATCNQ	SysPTM 2.0;curated	18327897; 19366988; 22817900
616	DATCNQNSNEPQDLK	SysPTM 2.0;curated	18327897; 19366988; 22817900
823	HLPHNVGSPLDAAHK	PHOSIDA;curated	21081558; 22817900
1360	AAAHRAASPASSVSS	PhosphoPep 2.0;curated	19060867; 22817900
1411	HALMRQQSPHMTPPP	SysPTM 2.0;curated	18327897; 19366988; 22817900
1415	RQQSPHMTPPPVSNA	SysPTM 2.0;curated	18327897; 19366988; 22817900
1445	GQRGLGTSPPPHLRP	curated	22817900
1715	HNIPRGPSPEAKPDD	PHOSIDA;PhosphoPep 2.0;curated	21081558; 19060867; 22817900

Sequence
(Fasta)

MAASTQGEIR VGPGHQVNDV YAKLPDYNPI SSFPIDKETD ERELEESRWS PGVVADGDLL 60
MFLRAARSMA AFQGMCDGGL EDGCLAASRD DTTINALDVL HDSGYDPGKA LQALVKCPVS 120
KGIDKKWTED ETKKFIKGLR QFGKNFFRIH KDLLPHKDTP ELVEFYYLWK KTPGANNNRP 180
HRRRRQSALR RNRVTRANNS NSNTPPKKED TPEPQTATTA TAAATAASET ASRSSPAVSK 240
EENSSLTEDD ASECDSDSSL THKRDESPSR MRTRNKQQNN NSSTSSGNNT AGNGGGNATS 300
ISSGSTGGGA AGGNSSSKDQ SANAVANGKR PKRGSETPDV SGGASVDSPK TPTKAVAESS 360
ANKRKGGKQD TPNKKKRTEQ ESNEPSAHEE NAIKEKRKRP DSPVESMNSD SRPDSVLDDG 420
ESNTTDTTTA EQQSTKDSKE TVSCKEEREM VTNDLEAKAE EKAIKAEALA EDSKDSAIKN 480
MDEETNIQAP SSADTSLVDG PNPNALPSPV AAPITMKVPT IATVEALNAS VDRKEAIEKM 540
ESCDSDPEML KKLATIKQEV SPQQQQHMQQ QSQQQMQQQL APVGIPQPPS CPPSESVYIK 600
KEPMEDSMDA TCNQNSNEPQ DLKVKIEIKN EDALKHSAGG LPPSGPCAPP SALHPLSGAP 660
VESGQEPLHL QHMPHGQVTT QPPPGYLIDG QLKYGPSGQG VPPQPPQLHS DAAGGVSGAP 720
PGAPTTPQKY PPEMEMKFAP QDLKYPPPPP LDALKYSQEM QAAAAAAAAA GKYDMKYMME 780
QQGKYNVELS AAHQPPSKPG YQDSLKIPDI KPGFGHLPHN VGSPLDAAHK YGPPPTSQES 840
QQQQPQPPAH QVPPGATPPP GIAMPKPHYQ HDVQTPPLGR PFEPTGLMLK YGDPLAAKYG 900
PPQDLKYPMP PVSQAGPADV KPYGGENLIK SSPYGPPPES PIDASARSTP GQDSQGSNSN 960
SQPPSMPPQP QQFQSPHPSP HMPSPAGGGL PPGMHPQNLI HGPPPGAAGG SGPQPPPPPT 1020
SLHQPTPTSA GPPSLQHGLH PGHQHSQLSV ASSIPPSSIG IPPTLSTMAP SHMHPHLHPH 1080
AHLQGLHRPH DLPPSMHPHA PMPLSLQGHP QHGHGLPPSH TSQQQQQQQQ QQQPGGPAGT 1140
VRTPSPAQQP PRSMHDPQSS REPPTSQPST TMAGSSGPGG PPPQQSPHAH RTSPLPGLAG 1200
SGPPPPGLIG HPMAIHPHLA HLPPGHPAHA ALAHPGHHLL SHSIAGLGPG GGPIALLAGP 1260
GGLGGIPESA LSRRTPPSHL PHSHASSAPL TAHSVASMTS TSMSLTTSTV PSSAFSRASP 1320
SVQISSSGGG PSGPGSVGPG GMPNSSAAAA AAAAAHRAAS PASSVSSLSR QSPLHPVPQS 1380
PLSHHPSSSA LSAAAAAVAE RDRHALMRQQ SPHMTPPPVS NASLMASPLS KMYAPQPGQR 1440
GLGTSPPPHL RPGASPPVIR HPQMPLPLPL IAPGGGIPQI GVHPGQSPYP HPLLHPSVFY 1500
SPHHHPFNSP YGYAPYGPGF PAYMKPPPQP GQLDPAAVMA AHHAGLQGPP PQQMRQDEQN 1560
AAAAAAQAAA EKQHQAAAAA AAQQHKAPQQ QQPGGMPPNK PPTPKTPQGP GGGMPPGMGG 1620
PGTPTGLPPG AYPGSHMPGY PQGPPHGSPF APQDGQPHGL KPTSHMDALR AHAHSANSAG 1680
MGGGHHPTEP LPIDIEPDPE PEIPSPTHNI PRGPSPEAKP DDTECHRSQS AIFVRHIDRG 1740
DYNSCTRTDL IFKPVADSKL ARKREERDRK LAEKERERRQ QQQQQQQQQQ QQQAAAAQQA 1800
AQQAKMKAEL KPPYADTPAL RQLSEYARPH VAFSPVEQMV PYHHPMGPMY RERELEEIKN 1860
AQAAAASQSR LDPHWMEYYR RGIHPSQFPL YANPAISQME RERLGIPPPH HVGLDPGEHM 1920
IRLTREYHAH SHTHLHLPLH PQPQPPEAGF QLPPNVGQYP RPNMLIPREP HSDVLLRMSY 1980
ADQLQYLQAA EFQRQSLHDQ YFRNQLR 2008

Fasta Sequence

>M9PHT1|Gug|Drosophila melanogaster(Fruit fly)
MAASTQGEIRVGPGHQVNDVYAKLPDYNPISSFPIDKETDERELEESRWSPGVVADGDLLMFLRAARSMAAFQGMCDGGLEDGCLAASRDDTTINALDVLHDSGYDPGKALQALVKCPVSKGIDKKWTEDETKKFIKGLRQFGKNFFRIHKDLLPHKDTPELVEFYYLWKKTPGANNNRPHRRRRQSALRRNRVTRANNSNSNTPPKKEDTPEPQTATTATAAATAASETASRSSPAVSKEENSSLTEDDASECDSDSSLTHKRDESPSRMRTRNKQQNNNSSTSSGNNTAGNGGGNATSISSGSTGGGAAGGNSSSKDQSANAVANGKRPKRGSETPDVSGGASVDSPKTPTKAVAESSANKRKGGKQDTPNKKKRTEQESNEPSAHEENAIKEKRKRPDSPVESMNSDSRPDSVLDDGESNTTDTTTAEQQSTKDSKETVSCKEEREMVTNDLEAKAEEKAIKAEALAEDSKDSAIKNMDEETNIQAPSSADTSLVDGPNPNALPSPVAAPITMKVPTIATVEALNASVDRKEAIEKMESCDSDPEMLKKLATIKQEVSPQQQQHMQQQSQQQMQQQLAPVGIPQPPSCPPSESVYIKKEPMEDSMDATCNQNSNEPQDLKVKIEIKNEDALKHSAGGLPPSGPCAPPSALHPLSGAPVESGQEPLHLQHMPHGQVTTQPPPGYLIDGQLKYGPSGQGVPPQPPQLHSDAAGGVSGAPPGAPTTPQKYPPEMEMKFAPQDLKYPPPPPLDALKYSQEMQAAAAAAAAAGKYDMKYMMEQQGKYNVELSAAHQPPSKPGYQDSLKIPDIKPGFGHLPHNVGSPLDAAHKYGPPPTSQESQQQQPQPPAHQVPPGATPPPGIAMPKPHYQHDVQTPPLGRPFEPTGLMLKYGDPLAAKYGPPQDLKYPMPPVSQAGPADVKPYGGENLIKSSPYGPPPESPIDASARSTPGQDSQGSNSNSQPPSMPPQPQQFQSPHPSPHMPSPAGGGLPPGMHPQNLIHGPPPGAAGGSGPQPPPPPTSLHQPTPTSAGPPSLQHGLHPGHQHSQLSVASSIPPSSIGIPPTLSTMAPSHMHPHLHPHAHLQGLHRPHDLPPSMHPHAPMPLSLQGHPQHGHGLPPSHTSQQQQQQQQQQQPGGPAGTVRTPSPAQQPPRSMHDPQSSREPPTSQPSTTMAGSSGPGGPPPQQSPHAHRTSPLPGLAGSGPPPPGLIGHPMAIHPHLAHLPPGHPAHAALAHPGHHLLSHSIAGLGPGGGPIALLAGPGGLGGIPESALSRRTPPSHLPHSHASSAPLTAHSVASMTSTSMSLTTSTVPSSAFSRASPSVQISSSGGGPSGPGSVGPGGMPNSSAAAAAAAAAHRAASPASSVSSLSRQSPLHPVPQSPLSHHPSSSALSAAAAAVAERDRHALMRQQSPHMTPPPVSNASLMASPLSKMYAPQPGQRGLGTSPPPHLRPGASPPVIRHPQMPLPLPLIAPGGGIPQIGVHPGQSPYPHPLLHPSVFYSPHHHPFNSPYGYAPYGPGFPAYMKPPPQPGQLDPAAVMAAHHAGLQGPPPQQMRQDEQNAAAAAAQAAAEKQHQAAAAAAAQQHKAPQQQQPGGMPPNKPPTPKTPQGPGGGMPPGMGGPGTPTGLPPGAYPGSHMPGYPQGPPHGSPFAPQDGQPHGLKPTSHMDALRAHAHSANSAGMGGGHHPTEPLPIDIEPDPEPEIPSPTHNIPRGPSPEAKPDDTECHRSQSAIFVRHIDRGDYNSCTRTDLIFKPVADSKLARKREERDRKLAEKERERRQQQQQQQQQQQQQQAAAAQQAAQQAKMKAELKPPYADTPALRQLSEYARPHVAFSPVEQMVPYHHPMGPMYRERELEEIKNAQAAAASQSRLDPHWMEYYRRGIHPSQFPLYANPAISQMERERLGIPPPHHVGLDPGEHMIRLTREYHAHSHTHLHLPLHPQPQPPEAGFQLPPNVGQYPRPNMLIPREPHSDVLLRMSYADQLQYLQAAEFQRQSLHDQYFRNQLR

Keyword

KW-0002--3D-structure
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR002951--Atrophin-like
IPR000949--ELM2_dom
IPR009057--Homeodomain-like
IPR001005--SANT/Myb
IPR017884--SANT_dom

PROSITE

PS51156--ELM2
PS51293--SANT

Pfam

PF03154--Atrophin-1
PF01448--ELM2

Gene Ontology

GO:0005634--C:nucleus
GO:0005705--C:polytene chromosome interband
GO:0003677--F:DNA binding
GO:0004407--F:histone deacetylase activity
GO:0070491--F:repressing transcription factor binding
GO:0003714--F:transcription corepressor activity
GO:0009880--P:embryonic pattern specification
GO:0001654--P:eye development
GO:0016575--P:histone deacetylation
GO:0007480--P:imaginal disc-derived leg morphogenesis
GO:0008586--P:imaginal disc-derived wing vein morphogenesis
GO:0002121--P:inter-male aggressive behavior
GO:0007526--P:larval somatic muscle development
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0045879--P:negative regulation of smoothened signaling pathway
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0035065--P:regulation of histone acetylation
GO:0007379--P:segment specification
GO:0035282--P:segmentation