dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053880
Uniprot Accession M0RE13; M0RE13_RAT;
Genbank Protein ID XP_006247883.1; XP_008766614.1;
Genbank Nucleotide ID XM_006247821.2; XM_008768392.1;
Protein Name Transmembrane channel-like protein
Protein Synonyms/Alias
Gene Name Tmc8
Gene Synonyms/Alias LOC688276;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
307RLLTYLRTNVLIVLLPhosphoSitePlus22135298
320LLVIGAISAIFWATKPhosphoSitePlus22135298
659SRLLPELSPEPESPHPhosphoSitePlus22135298
664ELSPEPESPHFRASRPhosphoSitePlus22135298
719ASRFHFPSLTEL---PhosphoSitePlus22135298
Sequence
(Fasta)		MFRQWSVQSG PAPRRSESQA SSEDLWKQEV ERLCASRTPV RMLPYAMADK RFIRELREPE 60
GVKNSCWQRW HRPRQVARQQ LGEAAKRLGR GFGLWEGALY EIGGLFGTGI QSYFTFLRFL 120
LLLNLLTMLL TACFVLLPLL WLRSPEPGPA LKLTGLQCSG SPLPQSDIPR FHNPLWNVLT 180
GRAFNNTYLF YGAYRAGPES SSAYSIRLAY LLSPLACLLL CFCVILQRMA EGLPQQTLVG 240
QRYRTPLSAK VFSSWDFCIR VWEAATIKKH EISNELKVEL EEGHRLELAQ QQTRAQKACR 300
LLTYLRTNVL IVLLVIGAIS AIFWATKYSQ DNKEESLFLV LQYLPPGVIA LVNFLGPQLF 360
TVLIQVENYP PSTEVNLTLF WCVVLKLVSL GMFSFSLGQT VLCIGRNKTS CETYGYNACD 420
YQCWENSVGE ELYKLIIFNF LLTVAFAFLV SLPRRLLVER FSGWFWTWLD REEFLVPKNV 480
LDIVAAQTVT WMGLFYCPLL SLLNSVFFFL TFYIKKYTLL RNSKASPRLF RASSSIFFFH 540
LVLLLGLLLA AVPLAYVISS THSSWDCGLF TNYSAPWQVV PELVALQLPL PGQYALHYLS 600
SHAFSFPLLF LLSLVLTVCI SQSRANARAI HELRKQLVWQ VQEKWHLVDD LSRLLPELSP 660
EPESPHFRAS RPRSFCPGFP CPGSPGPRTP WLGSSTRLSS SSLGTPSASV PASRFHFPSL 720
TEL 724
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR012496--TMC
PROSITE
Pfam

PF07810--TMC
Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0005794--C:Golgi apparatus
GO:0016021--C:integral component of membrane
GO:0031965--C:nuclear membrane
GO:0032091--P:negative regulation of protein binding
GO:0032460--P:negative regulation of protein oligomerization
GO:0001558--P:regulation of cell growth
GO:1902041--P:regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0055069--P:zinc ion homeostasis