dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053870
Uniprot Accession M0RDA4; M0RDA4_RAT;
Genbank Protein ID XP_001069453.1; XP_003751204.1;
Genbank Nucleotide ID XM_001069453.5; XM_003751156.3;
Protein Name Protein Ephb4
Protein Synonyms/Alias
Gene Name Ephb4
Gene Synonyms/Alias LOC686310;rCG_21674;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
614AKEIDVSYVKIEEVIPhosphoSitePlus22135298
769SRFLEENSSDPTYTSPhosphoSitePlus;curated22135298; 23712012; 21630457
Sequence
(Fasta)		MELRALLCWA SLATALEETL LNTKLETADL KWVTYPQAEG QWEELSGLDE EQHSVRTYEV 60
CDMKRPGGQA HWLRTGWVPR RGAVHVYATI RFTMMECLSL PRASRSCKET FTVFYYESEA 120
DTATAHTPAW MENPYIKVDT VAAEHLTRKR PGAEATGKVN IKTLRLGPLS KAGFYLAFQD 180
QGACMALLSL HLFYKKCSRL VTNLTYFPET VPRELVVPVA GSCVANAVPT ASPSPSLYCR 240
EDGQWAEQQV TGCSCAPGYE AAEGNKVCRA CGQGTFKPQI GEEPCLPCPA NSHSNNIGSP 300
VCLCRIGYYR ARSDPRSSPC TTPPSAPRSV VHHLNGSSLR LEWSAPLESG GREDLTYAVR 360
CRECRPGGSC LPCGGDLTFD PGPRDLVEPW VAIRGLRPDV TYTFEVAALN GVSTLATGPP 420
PFEPVNVTTD REVPPAVSDI RVTRSSPSSL ILSWAIPRAP SGAVLDYEVK YHEKGAEGPS 480
SVRFLKTSEN RAELRGLKQG ASYLVQVRAR SEAGYGPFGQ EHHSQTQLDE SESWREQLAL 540
IAGTAVVGVV LVLVVIIIAV LCLRKQSSGR EVEYSDKHGQ YLIGHGTKVY IDPFTYEDPN 600
EAVREFAKEI DVSYVKIEEV IGAGEFGEVC RGRLKAPGKK ESCVAIKTLK GGYTERQRRE 660
FLSEASIMGQ FEHPNIIRLE GVVTNSVPVM ILTEFMENGA LDSFLRLNDG QFTVIQLVGM 720
LRGIASGMRY LAEMSYVHRD LAARNILVNS NLVCKVSDFG LSRFLEENSS DPTYTSSLGG 780
KIPIRWTAPE AIAFRKFTSA SDAWSYGIVM WEVMSFGERP YWDMSNQDVI NAIEQDYRLP 840
PPPDCPTSLH QLMLDCWQKD RNARPRFPQV VSALDKMIRN PASLKIVARE NGGASHPLLD 900
QRQPHYSAFG SVGEWLRAIK MGRYEESFAA AGFGSFEVVS QISAEDLLRI GVTLAGHQKK 960
ILASVQHMKS QAKPGAPGGT GGPTQQF 988
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-0675--Receptor
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0829--Tyrosine-protein kinase
Interpro

IPR027936--Eph_TM
IPR001090--Ephrin_rcpt_lig-bd_dom
IPR003961--FN3_dom
IPR008979--Galactose-bd-like
IPR009030--Growth_fac_rcpt_N_dom
IPR013783--Ig-like_fold
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001660--SAM
IPR013761--SAM/pointed
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR011641--Tyr-kin_ephrin_A/B_rcpt-like
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
IPR016257--Tyr_kinase_ephrin_rcpt
IPR001426--Tyr_kinase_rcpt_V_CS
PROSITE

PS51550--EPH_LBD
PS50853--FN3
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS00790--RECEPTOR_TYR_KIN_V_1
PS00791--RECEPTOR_TYR_KIN_V_2
PS50105--SAM_DOMAIN
Pfam

PF14575--EphA2_TM
PF01404--Ephrin_lbd
PF00041--fn3
PF07699--GCC2_GCC3
PF07714--Pkinase_Tyr
PF00536--SAM_1
Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005887--C:integral component of plasma membrane
GO:0005524--F:ATP binding
GO:0005003--F:ephrin receptor activity
GO:0007155--P:cell adhesion
GO:0002042--P:cell migration involved in sprouting angiogenesis
GO:0046777--P:protein autophosphorylation