dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053866
Uniprot Accession M0RD40; M0RD40_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Protein Sik3
Protein Synonyms/Alias
Gene Name Sik3
Gene Synonyms/Alias LOC684112;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 11
PositionPeptidesSourceReferences ( PMIDs )
7-MAARIGYYEIDRTIPhosphoSitePlus22135298
8MAARIGYYEIDRTIGPhosphoSitePlus22135298
163TPGQLLKTWCGSPPYPhosphoSitePlus;curated22135298; 23984901
317RSDAYDHYSAIYSLLPhosphoSitePlus22135298
411YLSMRRHTVGVADPRPhosphoSitePlus;curated22135298; 23984901
493GPLGRRASDGGANIQPhosphoSitePlus;curated22135298; 23712012; 21630457; 22276854
527TPAVPAVTPVDEESScurated24945867
533VTPVDEESSDGEPDQPhosphoSitePlus;curated22135298; 24945867
534TPVDEESSDGEPDQEPhosphoSitePlus22135298
616FSPVRRFSDGAASIQPhosphoSitePlus;curated22135298; 23984901
856RPLSKQLSADSAEAHPhosphoSitePlus22135298
Sequence
(Fasta)		MAARIGYYEI DRTIGKGNFA VVKRATHLVT KAKVAIKIID KTQLDEENLK KIFREVQIMK 60
MLCHPHIIRL YQVMETERMI YLVTEYASGG EIFDHLVAHG RMAEKEARRK FKQIVTAVYF 120
CHCRNIVHRD LKAENLLLDA NLNIKIADFG FSNLFTPGQL LKTWCGSPPY AAPELFEGKE 180
YDGPKVDIWS LGVVLYVLVC GALPFDGSTL QNLRARVLSG KFRIPFFMST ECEHLIRHML 240
VLDPNKRLSM EQICRHRWMK LGDADPNFER LIAECQQLKE ERQAEPLNDE VLLAMEDMGL 300
DKERTLQSLR SDAYDHYSAI YSLLCDRHKK NKTLRPGALP STPQAMTFQA PVNIQAEQTG 360
TAMNISVPQV QLINPENQII EPDGAVNLDS DEGEEPSPEA LVRYLSMRRH TVGVADPRTE 420
VMDEMQKLLP GFPGANPQTP FLQVAPNMNF MHNLLPMQSL QPTGQLEYKE QSLLQPPTLQ 480
LLNGMGPLGR RASDGGANIQ LHAQQLLKRP RGPSPLVTMT PAVPAVTPVD EESSDGEPDQ 540
EAVQRYLANR SKRHTLAMTS PTAEIPPDLQ RQLGQQSFRS RVWPPHLVPD QHRSTYKDSN 600
TLHLPTERFS PVRRFSDGAA SIQAFKAHLE RMGNSSSIKQ LQQECEQLQK MYGGQVDERT 660
LEKTQQQHML YQQEQHHQIL QQQIQDSICP PQPSPPLQAA CENQPTLLTH QLQRLRIQPS 720
SPPPNHPSNH LFRQPSNSPP PVSSAMISSH GATSPSQFQG LPSHGAIFQQ QPENCSPPPS 780
VALTCLGLQQ ASQSQPVTIQ LQEPVDMLSN MAGTTAGSAG RGIPISPSAS QIQMQHRTSL 840
MAPFGYGHRP LSKQLSADSA EAHSLSMNRF SPANYDQAHL HPHLFSEQSR GPPSSYSPST 900
GVGFPPAQAL RVPPLDQFPT FPPSAHQQPH YTTSALQQAL LSPTPPDYTR HQQVPHILQG 960
LLSPRHSLTG HSDIRLPPAE FAQLIKRQQQ HRQQQQQQQQ QQQQEYHELF RHMNQGDAVS 1020
LAPGLGGQNM TEHQALSYQN ADSYHRHHTS PQHLLQIRAQ DCISQGPLPT PTRGYARQSP 1080
LMHSESMEED CLCEGVKEGF ADKSSSTLTK GCHDSPLLLC TSGPGDPEPL LGTVSQAREL 1140
GIHPYGHQPT ATTFSRNKVP SRESVIGNCM ERSSPGQAME LPDHNGLGYP ARPLVSEHLR 1200
SRTLQRHHTI QNSDDAYVQL DTLPGMSLVA GKALSSARMS DAVLSQSSLM GSQQFQDEED 1260
EECGVSLGHE HPALGDGSQH LNSRYPATCV TDIMLNHKHP EVSFSMEQAG V 1312
Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA
Pfam

PF00069--Pkinase
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0060351--P:cartilage development involved in endochondral bone morphogenesis
GO:0001958--P:endochondral ossification
GO:0035108--P:limb morphogenesis
GO:0035264--P:multicellular organism growth
GO:0032880--P:regulation of protein localization