dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053863
Uniprot Accession M0RCN5; M0RCN5_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Frizzled homolog 3 (Drosophila), isoform CRA_a
Protein Synonyms/Alias
Gene Name Fzd3
Gene Synonyms/Alias rCG_52201;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
373YDVDALRYFVLAPLCPhosphoSitePlus22135298
382VLAPLCLYVVVGVSLPhosphoSitePlus22135298
Sequence
(Fasta)
MAVSWIVFYL WLLTVFLGQI GGHSLFSCEP ITLRMCQDLP YNTTFMPNLL NHYDQQTAAL 60
AMEPFHPMVN LDCSRDFRPF LCALYAPICM EYGRVTLPCR RLCQRAYSEC SKLMEMFGVP 120
WPEDMECSRF PDCDEPYPRL VDLNLVGDPT EGAPVAVQRD YGFWCPRELK IDPDLGYSFL 180
HVRDCSPPCP NMYFRREELS FARYFIGLIS IICLSATLFT FLTFLIDVTR FRYPERPIIF 240
YAVCYMMVSL IFFIGFLLED RVACNASSPA QYKASTVTQG SHNKACTMLF MVLYFFTMAG 300
SVWWVILTIT WFLAAVPKWG SEAIEKKALL FHASAWGIPG TLTIILLAMN KIEGDNISGV 360
CFVGLYDVDA LRYFVLAPLC LYVVVGVSLL LAGIISLNRV RIEIPLEKEN QDKLVKFMIR 420
IGVFSILYLV PLLVVIGCYF YEQAYRGIWE TTWIQERCRE YHIPCPYQVT QMSRPDLILF 480
LMKYLMALIV GIPSIFWVGS KKTCFEWASF FHGRKKKETV NESRQVLQEP DFAQSLLRDP 540
NTPIIRKSRG TSTQGTSTHA SSTQLAMVDD QRSKAGSVHS KVSSYHGSLH RSRDGRYTPC 600
SYRGMEERLP HGSMSRLTDH SRHSSSHRLN EQSRHSSIRD LSNNPMTHIT HGTSMNRVIE 660
EDGTSA 667
Keyword

KW-0181--Complete proteome
KW-0217--Developmental protein
KW-1015--Disulfide bond
KW-0472--Membrane
KW-0675--Receptor
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0879--Wnt signaling pathway

Interpro

IPR000539--Frizzled
IPR015526--Frizzled/SFRP
IPR020067--Frizzled_dom
IPR026553--FZD3_vertebrates
IPR017981--GPCR_2-like

PROSITE

PS50038--FZ
PS50261--G_PROTEIN_RECEP_F2_4

Pfam

PF01534--Frizzled
PF01392--Fz

Gene Ontology

GO:0016324--C:apical plasma membrane
GO:0030424--C:axon
GO:0005737--C:cytoplasm
GO:0030425--C:dendrite
GO:0032433--C:filopodium tip
GO:0016021--C:integral component of membrane
GO:0016328--C:lateral plasma membrane
GO:0043025--C:neuronal cell body
GO:0048786--C:presynaptic active zone
GO:0042813--F:Wnt-activated receptor activity
GO:0060070--P:canonical Wnt signaling pathway
GO:0033278--P:cell proliferation in midbrain
GO:0071679--P:commissural neuron axon guidance
GO:0001736--P:establishment of planar polarity
GO:0001942--P:hair follicle development
GO:0042472--P:inner ear morphogenesis
GO:1900118--P:negative regulation of execution phase of apoptosis
GO:0045976--P:negative regulation of mitotic cell cycle, embryonic
GO:0001843--P:neural tube closure
GO:0001764--P:neuron migration
GO:0002052--P:positive regulation of neuroblast proliferation
GO:0036342--P:post-anal tail morphogenesis
GO:0061549--P:sympathetic ganglion development