Tag |
Content |
dbPAF ID |
dbPAF-0053863 |
Uniprot Accession |
M0RCN5; M0RCN5_RAT; |
Genbank Protein ID |
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Genbank Nucleotide ID |
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Protein Name |
Frizzled homolog 3 (Drosophila), isoform CRA_a |
Protein Synonyms/Alias |
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Gene Name |
Fzd3 |
Gene Synonyms/Alias |
rCG_52201; |
Organism |
Rattus norvegicus(Rat) |
NCBI Taxa ID |
10116 |
Functional Description (View all) |
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Phosphorylation Sites
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dbPAF PTMs: 2 Position | Peptides | Source | References ( PMIDs ) |
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373 | YDVDALRYFVLAPLC | PhosphoSitePlus | 22135298 | 382 | VLAPLCLYVVVGVSL | PhosphoSitePlus | 22135298 |
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Sequence (Fasta) | MAVSWIVFYL WLLTVFLGQI GGHSLFSCEP ITLRMCQDLP YNTTFMPNLL NHYDQQTAAL 60 AMEPFHPMVN LDCSRDFRPF LCALYAPICM EYGRVTLPCR RLCQRAYSEC SKLMEMFGVP 120 WPEDMECSRF PDCDEPYPRL VDLNLVGDPT EGAPVAVQRD YGFWCPRELK IDPDLGYSFL 180 HVRDCSPPCP NMYFRREELS FARYFIGLIS IICLSATLFT FLTFLIDVTR FRYPERPIIF 240 YAVCYMMVSL IFFIGFLLED RVACNASSPA QYKASTVTQG SHNKACTMLF MVLYFFTMAG 300 SVWWVILTIT WFLAAVPKWG SEAIEKKALL FHASAWGIPG TLTIILLAMN KIEGDNISGV 360 CFVGLYDVDA LRYFVLAPLC LYVVVGVSLL LAGIISLNRV RIEIPLEKEN QDKLVKFMIR 420 IGVFSILYLV PLLVVIGCYF YEQAYRGIWE TTWIQERCRE YHIPCPYQVT QMSRPDLILF 480 LMKYLMALIV GIPSIFWVGS KKTCFEWASF FHGRKKKETV NESRQVLQEP DFAQSLLRDP 540 NTPIIRKSRG TSTQGTSTHA SSTQLAMVDD QRSKAGSVHS KVSSYHGSLH RSRDGRYTPC 600 SYRGMEERLP HGSMSRLTDH SRHSSSHRLN EQSRHSSIRD LSNNPMTHIT HGTSMNRVIE 660 EDGTSA
667Fasta Sequence
>M0RCN5|Fzd3|Rattus norvegicus(Rat) MAVSWIVFYLWLLTVFLGQIGGHSLFSCEPITLRMCQDLPYNTTFMPNLLNHYDQQTAALAMEPFHPMVNLDCSRDFRPFLCALYAPICMEYGRVTLPCRRLCQRAYSECSKLMEMFGVPWPEDMECSRFPDCDEPYPRLVDLNLVGDPTEGAPVAVQRDYGFWCPRELKIDPDLGYSFLHVRDCSPPCPNMYFRREELSFARYFIGLISIICLSATLFTFLTFLIDVTRFRYPERPIIFYAVCYMMVSLIFFIGFLLEDRVACNASSPAQYKASTVTQGSHNKACTMLFMVLYFFTMAGSVWWVILTITWFLAAVPKWGSEAIEKKALLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFVGLYDVDALRYFVLAPLCLYVVVGVSLLLAGIISLNRVRIEIPLEKENQDKLVKFMIRIGVFSILYLVPLLVVIGCYFYEQAYRGIWETTWIQERCREYHIPCPYQVTQMSRPDLILFLMKYLMALIVGIPSIFWVGSKKTCFEWASFFHGRKKKETVNESRQVLQEPDFAQSLLRDPNTPIIRKSRGTSTQGTSTHASSTQLAMVDDQRSKAGSVHSKVSSYHGSLHRSRDGRYTPCSYRGMEERLPHGSMSRLTDHSRHSSSHRLNEQSRHSSIRDLSNNPMTHITHGTSMNRVIEEDGTSA
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Keyword |
KW-0181--Complete proteome KW-0217--Developmental protein KW-1015--Disulfide bond KW-0472--Membrane KW-0675--Receptor KW-1185--Reference proteome KW-0732--Signal KW-0812--Transmembrane KW-1133--Transmembrane helix KW-0879--Wnt signaling pathway
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Interpro |
IPR000539--Frizzled IPR015526--Frizzled/SFRP IPR020067--Frizzled_dom IPR026553--FZD3_vertebrates IPR017981--GPCR_2-like
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PROSITE |
PS50038--FZ PS50261--G_PROTEIN_RECEP_F2_4
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Pfam |
PF01534--Frizzled PF01392--Fz
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Gene Ontology |
GO:0016324--C:apical plasma membrane GO:0030424--C:axon GO:0005737--C:cytoplasm GO:0030425--C:dendrite GO:0032433--C:filopodium tip GO:0016021--C:integral component of membrane GO:0016328--C:lateral plasma membrane GO:0043025--C:neuronal cell body GO:0048786--C:presynaptic active zone GO:0042813--F:Wnt-activated receptor activity GO:0060070--P:canonical Wnt signaling pathway GO:0033278--P:cell proliferation in midbrain GO:0071679--P:commissural neuron axon guidance GO:0001736--P:establishment of planar polarity GO:0001942--P:hair follicle development GO:0042472--P:inner ear morphogenesis GO:1900118--P:negative regulation of execution phase of apoptosis GO:0045976--P:negative regulation of mitotic cell cycle, embryonic GO:0001843--P:neural tube closure GO:0001764--P:neuron migration GO:0002052--P:positive regulation of neuroblast proliferation GO:0036342--P:post-anal tail morphogenesis GO:0061549--P:sympathetic ganglion development
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