dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0053856 |
| Uniprot Accession | M0RC77; M0RC77_RAT; |
| Genbank Protein ID | NP_001104836.1; |
| Genbank Nucleotide ID | NM_001111366.1; |
| Protein Name | Kynurenine formamidase |
| Protein Synonyms/Alias | |
| Gene Name | Afmid |
| Gene Synonyms/Alias | rCG_34031; |
| Organism | Rattus norvegicus(Rat) |
| NCBI Taxa ID | 10116 |
| Functional Description (View all) |
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MALPSSPSPG QAPWRTLSSE ELEKQYSPRR WVIRMKTEEV VGNFMQIGSQ ATQKARATRR 60 NQLDVSYGDG VGEKMDIYFP DEDSKAFPLF MFLHGGYWQS GSKDDSAFMV NPLTAQGIVV 120 AVVAYDIAPK GTLDQMVDQV SRSVVFLQRR YPSNEGIYLC GHSAGAHLAA MMLLASWTKH 180 GVTPNIQGLL LVSGIYDLEP LVFTSQNDLL HMTLEDAERN SPQRLLEVAP ARPVVPAYPV 240 LVFVAQHDSP EFHRQSKEFC ETLRLAGWKA SFQELCGVDH FDIIENLTRE DYALTQIILK 300 MIFQKL 307 |
| Keyword | KW-0181--Complete proteome |
| Interpro | IPR029058--AB_hydrolase |
| PROSITE | |
| Pfam | PF07859--Abhydrolase_3 |
| Gene Ontology | GO:0005829--C:cytosol |