dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053815
Uniprot Accession M0RAA8; M0RAA8_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Protein Tlr9
Protein Synonyms/Alias
Gene Name Tlr9
Gene Synonyms/Alias rCG_25765;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
69RSNITSLSLIANRIHPhosphoSitePlus22135298
Sequence
(Fasta)		MVLCRRTLHP LSLLVQAAML AEALALGTLP AFLPCELKPH GLVDCNWLFL KSVPHFSAAE 60
PRSNITSLSL IANRIHHLHN LDFVHLPNVR QLNLKWNCPP PGLSPLHFSC RMTIEPKTFL 120
AMRMLEELNL SYNGITTVPR LPSSLTNLSL SHTNILVLDA SSLAGLHSLR VLFMDGNCYY 180
KNPCNGAVNV TPDAFLGLSN LTHLSLKYNN LTEVPRQLPS SLEYLLLSYN LIVKLGPEDL 240
ANLTSLRVLD VGGNCRRCDH APDLCTECRQ KSLDLHPQTF RHLSHLEGLV LKDSSLHSLN 300
SKWFQGLVNL SVLDLSENFL YESINKTSAF QNLTRLRKLD LSFNYCKKVS FARLHLASSF 360
KSLVSLQELN MNGIFFRLLN KNTLRWLAGL PKLHTLHLQM NFINQAQLSV FSTFRALRFV 420
DLSNNRISGP PTLSRVAPEK ADEAEKGVPW PASLTPALPS TPVSKNFMVR CKNLRFTMDL 480
SRNNLVTIKP EMFVNLSHLQ CLSLSHNCIA QAVNGSQFLP LTNLKVLDLS YNKLDLYHSK 540
SFSELPQLQA LDLSYNSQPF SMQGIGHNFS FLANLSRLQN LSLAHNDIHS RVSSRLYSTS 600
VEYLDFSGNG VGRMWDEEDL YLYFFQDLRS LIHLDLSQNK LHILRPQNLN YLPKSLTKLS 660
FRDNHLSFFN WSSLAFLPNL RDLDLAGNLL KALTNGTLPN GTLLQKLDVS SNSIVFVVPA 720
FFALAVELKE VNLSHNILKT VDRSWFGPIV MNLTVLDVSS NPLHCACGAP FVDLLLEVQT 780
KVPGLANGVK CGSPRQLQGR SIFAQDLRLC LDDVLSRDCF GLSLLAVAVG TVLPLLQHLC 840
GWDVWYCFHL CLAWLPLLTR GRRSAQALPY DAFVVFDKAQ SAVADWVYNE LRVRLEERRG 900
RRALRLCLED RDWLPGQTLF ENLWASIYGS RKTLFVLAHT DKVSGLLRTS FLLAQQRLLE 960
DRKDVVVLVI LRPDAHRSRY VRLRQRLCRQ SVLFWPHQPN GQGSFWAQLS TALTRDNHHF 1020
YNRNFCRGPT AE 1033
Keyword

KW-0181--Complete proteome
KW-0433--Leucine-rich repeat
KW-0675--Receptor
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
Interpro

IPR001611--Leu-rich_rpt
IPR003591--Leu-rich_rpt_typical-subtyp
IPR000157--TIR_dom
IPR027181--TLR9
PROSITE

PS51450--LRR
PS50104--TIR
Pfam

PF13855--LRR_8
PF01582--TIR
Gene Ontology

GO:0032009--C:early phagosome
GO:0005783--C:endoplasmic reticulum
GO:0005768--C:endosome
GO:0016021--C:integral component of membrane
GO:0005764--C:lysosome
GO:0004888--F:transmembrane signaling receptor activity
GO:0051607--P:defense response to virus
GO:0045087--P:innate immune response
GO:0030277--P:maintenance of gastrointestinal epithelium
GO:0002755--P:MyD88-dependent toll-like receptor signaling pathway
GO:0032715--P:negative regulation of interleukin-6 production
GO:0050729--P:positive regulation of inflammatory response
GO:0032728--P:positive regulation of interferon-beta production
GO:0032733--P:positive regulation of interleukin-10 production
GO:0032735--P:positive regulation of interleukin-12 production
GO:0032741--P:positive regulation of interleukin-18 production
GO:0051770--P:positive regulation of nitric-oxide synthase biosynthetic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:0050864--P:regulation of B cell activation
GO:0050707--P:regulation of cytokine secretion
GO:0002730--P:regulation of dendritic cell cytokine production
GO:0001932--P:regulation of protein phosphorylation
GO:0002237--P:response to molecule of bacterial origin
GO:0034162--P:toll-like receptor 9 signaling pathway