dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053805
Uniprot Accession M0R9T2; M0R9T2_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Protein Erbb2ip
Protein Synonyms/Alias
Gene Name Erbb2ip
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 27 (View all)
PositionPeptidesSourceReferences ( PMIDs )
193RLKNLPFSFTKLQQLcurated23712012
195KNLPFSFTKLQQLTAcurated23712012
232QKMVLTNYMFPQQPRPhosphoSitePlus22135298
247TEDVMFISDNESFNPPhosphoSitePlus22135298
292GNLKRYPTPYPDELKcurated23984901
372TSEPEAETNAGNSPVcurated23712012; 21630457
377AETNAGNSPVTTNRKPhosphoSitePlus;curated22135298; 23712012; 21630457
380NAGNSPVTTNRKSSGcurated21630457
381AGNSPVTTNRKSSGNcurated21630457
402HDDVFEESEELSSDEPhosphoSitePlus22135298
406FEESEELSSDEEMKMPhosphoSitePlus;curated22135298; 21630457
407EESEELSSDEEMKMAPhosphoSitePlus;curated22135298; 21630457
519NGVNLNNSPEEKFKIPhosphoSitePlus;curated22135298; 23712012; 21630457
633VNGLSEDTAQSPGRIcurated21630457
636LSEDTAQSPGRIEPQcurated23712012; 21630457
646RIEPQNTSPADVGISPhosphoSitePlus;curated22135298; 23712012; 21630457
656DVGISKSTEDLSPQRcurated23712012; 21630457
660SKSTEDLSPQRSGPAPhosphoSitePlus;curated22135298; 23712012; 21630457
675GSVVKSHSITNMETGPhosphoSitePlus;curated22135298; 23984901
687ETGGLKIYDILSDDGcurated21630457
Sequence
(Fasta)
MNSQEVPEVL EQLSGLREFW MDGNRLTFIP GFIGSLRQLT YLDVSKNNIE MVEEGISTCE 60
NLQDFLLSSN SLQQLPETIG SLKNVTTLKI DENQLMYLPD SIGGLRSIEE LDCSFNEIEA 120
LPSSIGQLTN IRTFAADHNY LQQLPPEIGN WKNVTVLFLH SNKLETLPEE MGDMQKLKVI 180
NLSDNRLKNL PFSFTKLQQL TAMWLSDNQS KPLIPLQKET DSETQKMVLT NYMFPQQPRT 240
EDVMFISDNE SFNPALWEEQ RKQRAQVAFE CDEDKDEREA PPREGNLKRY PTPYPDELKN 300
MVKTVQTIVH RLKDEETNEE SGRDLKQHED QQVVNKDKGV KPSESITTKS KLDEREKYMN 360
SVPKTSEPEA ETNAGNSPVT TNRKSSGNMK HLVNHDDVFE ESEELSSDEE MKMAEMRPPL 420
IETSINQPKV VALSNNKKDD AKDTDSLSDE VTHNSNQNNS NCSSPSRMSD SVSLNTDSSQ 480
DTALCSPAKQ IPIDSNSKIR QEDENFNSLL QNGVNLNNSP EEKFKINDKK DFKLPEYDLN 540
IEEQLVLIEK DVDSKATSED SHQLDHINMN LNKLVTNNIF QPEIMERSKM QDIVLGTGFL 600
SIHSKSEAEH IENGNKFLNS ESINKVNGLS EDTAQSPGRI EPQNTSPADV GISKSTEDLS 660
PQRSGPAGSV VKSHSITNME TGGLKIYDIL SDDGPQPPGA TVKVASTMDG KNIVRSKSAT 720
LLYDQPLQVF TASSSSSELL SGTKAVFKFD SNHNPEDPDI IRASIVPGPQ SIPQLYGPPQ 780
YNVQYSGSAA MKDTLWHPKQ NPQIDPVSFP PQRLPRSESA ENHSYTKHSA NMNFSNHNNV 840
RANTAYHLHQ RLAPTRHGEM WAVSPNDRLV PAVSRTTVQR QSSVSSTASV NLGDPGPTRR 900
TEGDYLSYRE LHSMGRTPVT SGSQRPLSAR AFSIDGPSTS RPQSARPSIS EIPERTMSVS 960
DFNYSRTSPS KRPNARVGSE HSLLDPPGKS KVPHDWREQV LRHIEAKKLE KSMLSRSFSS 1020
NLTAVSSSHY GSSRDLHGSQ GSLALNVADG RGSGGHSFRH PQTSSPGDCC QDDRFMSGEQ 1080
NHPLGALSHR DLRDSLMKMP LSNGQMGQPL RPQANYSQTH HPPQASVARH PSREQLIDYL 1140
MLKVAHQPPY THPHCSPRQG HELAKQEIRV RVEKDPELGF SISGGVGGRG NPFRPDDDGI 1200
FVTRVQPEGP ASKLLQPGDK IIQANGYSFI NIEHGQAVSL LKTFHNAVEL IIVREVSS 1259
Keyword

KW-0181--Complete proteome
KW-0433--Leucine-rich repeat
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR001611--Leu-rich_rpt
IPR003591--Leu-rich_rpt_typical-subtyp
IPR001478--PDZ

PROSITE

PS51450--LRR
PS50106--PDZ

Pfam

PF13855--LRR_8
PF00595--PDZ

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0005737--C:cytoplasm
GO:0030056--C:hemidesmosome
GO:0005654--C:nucleoplasm
GO:0071356--P:cellular response to tumor necrosis factor
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0070433--P:negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0010628--P:positive regulation of gene expression
GO:0032496--P:response to lipopolysaccharide
GO:0032495--P:response to muramyl dipeptide