dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053782
Uniprot Accession M0R8T7; M0R8T7_RAT;
Genbank Protein ID NP_958738.1;
Genbank Nucleotide ID NM_201350.1;
Protein Name SH3 and multiple ankyrin repeat domains protein 2
Protein Synonyms/Alias
Gene Name Shank2
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
752ALTLRSKSMTAELEEcurated23984901
Sequence
(Fasta)
MPRSPTSSED EMAQSFSDYS VGSESDSSKE ETIYDTIRAT TEKPGGVKME DLQGNTLVIR 60
VVIQDLQQTK CIRFNPDATV WVAKQRILCT LNQGLKDVLN YGLFQPASNG RDGKFLDEER 120
LLREYPQPMG QGVPSLEFRY KKRVYKQSNL DEKQLARLHT KTNLKKFMDH TQHRSVEKLV 180
KLLDRGLDPN FHDLETGETP LTLAAQLDGS MEVIKALRNG GAHLDFRSRD GMTALHKAAR 240
MRNQVALKTL LELGASPDYK DSYGLTPLYH TAIVGGDPYC CELLLHEHAS VCCKDENGWH 300
EIHQACRYGH VQHLEHLLFY GADMSAQNAS GNTALHICAL YNQDSCARVL LFRGGDKELK 360
NYNSQTPFQV AIIAGNFELA EYIKNHKETD IVPFREAPAY SNRRRRPPNT LAAPRVLLRS 420
NSDNNLNAGA PEWAVCSAAT SHRSLSPQLL QQTPSKPDGA TKSLGSYAPG PRSRSPSLNR 480
LGGAGEDGKR PQPPHWHVGS PFTPGANKDS LSTFEYPGPR RKLYSAVPGR LFVAIKPYQP 540
QVDGEIPLHR GDRVKVLSIG EGGFWEGSAR GHIGWFPAEC VEEVQCKPRD SQAETRADRS 600
KKLFRHYTVG SYDSFDAASD CIIEDKTVVL QKKDNEGFGF VLRGAKADTP IEEFTPTPAF 660
PALQYLESVD EGGVAWQAGL RTGDFLIEVN NENVVKVGHR QVVNMIRQGG NHLVLKVVTV 720
TRNLDPDDTA RKKAPPPPKR APTTALTLRS KSMTAELEEL DKPEEIVPAS KPSRTAENVA 780
IESRVATIKQ RPTSRCFPAA SDVNSVYERQ GIAVMTPTVP GSPKGPFLGL PRGTMRRQKS 840
IDSRIFLSGI TEEERQFLAP PMLKFTRSLS MPDTSEDIPP PPQSVPPSPP PPSPTTYNCP 900
RSPTPRVYGT IKPAFNQNPV AKVPPATRSD TVATMMREKG MFYRRELDRF SLDSEDVYSR 960
SPAPQAAFRT KRGQMPENPY SEVGKIASKA VYVPAKPARR KGMLVKQSNV EDSPEKTCSI 1020
PIPTIIVKEP STSSSGKSSQ GSSMEIDPQA TEPGQLRPDD SLTVSSPFAA AIAGAVRDRE 1080
KRLEARRNSP AFLSTDLGDE DVGLGPPAPR MQPSKFPEEG GFGDEDETEQ PLLPTPGAAP 1140
RELENHFLGG GEAGAQGEAG GPLSSTSKAK GPESGPAAAL KSSSPASPEN YVHPLTGRLL 1200
DPSSPLALAL SARDRAMQES QQGHKGEAPK ADLNKPLYID TKMRPSVESG FPPVTRQNTR 1260
GPLRRQETEN KYETDLSKDR RADDKKNMLI NIVDTAQQKS AGLLMVHTVD IPVAGPPLEE 1320
EEDREDGDTK PDHSPSTVPE GVPKTEGALQ ISAAPEPAAA PGRTIVAAGS VEEAVILPFR 1380
IPPPPLASVD LDEDFLFTEP LPPPLEFANS FDIPDDRAAS VPALADLVKQ KKSDTPQPPS 1440
LNSSQPANST DSKKPAGISN CLPSSFLPPP ESFDAVTDSG IEEVDSRSSS DHHLETTSTI 1500
STVSSISTLS SEGGESMDTC TVYADGQAFV VDKPPVPPKP KMKPIVHKSN ALYQDTLPEE 1560
DTDGFVIPPP APPPPPGSAQ AGVAKVIQPR TSKLWGDVTE VKSPILSGPK ANVISELNSI 1620
LQQMNRGKSV KPGEGLELPV GAKSANLAPR SPEVMSTVSG TRSTTVTFTV RPGTSQPITL 1680
QSRPPDYESR TSGPRRAPSP VVSPTELSKE ILPTPPSAAA ASPSPTLSDV FSLPSQSPAG 1740
DLFGLNPAGR SRSPSPSILQ QPISNKPFTT KPVHLWTKPD VADWLESLNL GEHKETFMDN 1800
EIDGSHLPNL QKEDLIDLGV TRVGHRMNIE RALKQLLDR
Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR032425--FERM_f0
IPR001478--PDZ
IPR001660--SAM
IPR013761--SAM/pointed
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50106--PDZ
PS50105--SAM_DOMAIN
PS50002--SH3

Pfam

PF12796--Ank_2
PF16511--FERM_f0
PF00595--PDZ
PF00536--SAM_1
PF07653--SH3_2

Gene Ontology

GO:0031526--C:brush border membrane
GO:0030426--C:growth cone
GO:0043025--C:neuronal cell body
GO:0014069--C:postsynaptic density
GO:0008022--F:protein C-terminus binding
GO:0017124--F:SH3 domain binding
GO:0007420--P:brain development
GO:0007584--P:response to nutrient