dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053767
Uniprot Accession M0R7V5; M0R7V5_RAT;
Genbank Protein ID XP_001060914.4; XP_003748704.2;
Genbank Nucleotide ID XM_001060914.5; XM_003748656.3;
Protein Name Protein Tnfaip3
Protein Synonyms/Alias
Gene Name Tnfaip3
Gene Synonyms/Alias LOC683206;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
589SCHQRSKSDPSQLIQcurated23984901
Sequence
(Fasta)
MTRSNTGVSC RQVYGSSVKG RLTEWAFPLP LQALSRTMAE QLLPQALYLS NMRKAVKIRE 60
RTPEDIFKPS NGIIHHFKTM HRYTLEMFRT CQFCPQFREI IHKALIDRSV QASLESQKKL 120
NWCREVRKLV ALKTNGDGNC LMHAACQYMW GVQDTDLVLR KALCSTLKET DTRNFKFRWQ 180
LESLKSQEFV ETGLCYDTRN WNDEWDNLVK MASADTPAAR SGLQYNSLEE IHIFVLSNIL 240
RRPIIVISDK MLRSLESGSN FAPLKVGGIY LPLHWPAQEC YRYPIVLGYD SQHFVPLVTL 300
KDSGPEIRAV PLVNRERGRF EDLKVHFLTD PEHEMKEKLL KEYLMVLEIP VQGWDHGTTH 360
LINAAKLDEA NLPKEINLVD DYFELVQHEY KKWQENGDQG RRGAHAQNPL EASTPQLSLM 420
DIKCETPNCP FFMSVNTQPL CHECSERRQK NQSKLPKLNS KLGPEGGLPA VGLGSSNWNP 480
EETAGGPHSA PPTAPSLFLF SETTAMKCRS PGCPFTLNVQ HNGFCERCHN ARQMSASHTA 540
DPGKCQACLQ DVTRTFNGIC STCFKRTTAE PTSSLTSSVP PSCHQRSKSD PSQLIQSLTP 600
HSCHRTGNAV PSGYLSQTSR TPADRTGTSK CRKAGCMYFG TPENKGFCTL CFIEYRENKQ 660
SVTASGKAAS SAPRFQNNIP CLGRECGTLG STMFEGYCQK CFIEAQNQRF HEAKRPEEQL 720
RSSQRREMPR TTQGASRPKC ARASCKNILA CRSEELCMEC QHLSQRIASL AHRGEPTPEE 780
PPKQRCRAPA CDHFGNAKCN GYCNECYQFK QMYG 815
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU
PF01754--zf-A20

Gene Ontology

GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0070530--F:K63-linked polyubiquitin binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0004843--F:ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0001922--P:B-1 B cell homeostasis
GO:0070301--P:cellular response to hydrogen peroxide
GO:0072666--P:establishment of protein localization to vacuole
GO:0050869--P:negative regulation of B cell activation
GO:2000349--P:negative regulation of CD40 signaling pathway
GO:0002677--P:negative regulation of chronic inflammatory response
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:2000352--P:negative regulation of endothelial cell apoptotic process
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045824--P:negative regulation of innate immune response
GO:0032691--P:negative regulation of interleukin-1 beta production
GO:0032703--P:negative regulation of interleukin-2 production
GO:0032715--P:negative regulation of interleukin-6 production
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0070429--P:negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
GO:0070433--P:negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0031397--P:negative regulation of protein ubiquitination
GO:0048662--P:negative regulation of smooth muscle cell proliferation
GO:0034140--P:negative regulation of toll-like receptor 3 signaling pathway
GO:0034148--P:negative regulation of toll-like receptor 5 signaling pathway
GO:0032720--P:negative regulation of tumor necrosis factor production
GO:1903364--P:positive regulation of cellular protein catabolic process
GO:2000347--P:positive regulation of hepatocyte proliferation
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0002634--P:regulation of germinal center formation
GO:0050727--P:regulation of inflammatory response
GO:0045088--P:regulation of innate immune response
GO:0032495--P:response to muramyl dipeptide
GO:0072573--P:tolerance induction to lipopolysaccharide