dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053763
Uniprot Accession M0R7T1; M0R7T1_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Phosphatase and actin regulator
Protein Synonyms/Alias
Gene Name Phactr4
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 23 (View all)
PositionPeptidesSourceReferences ( PMIDs )
41DSVEAGDTTPPTKRKPhosphoSitePlus22135298
42SVEAGDTTPPTKRKSPhosphoSitePlus22135298
130TPIGSVRSSSPILSEPhosphoSitePlus22135298
131PIGSVRSSSPILSEEcurated23712012; 21630457
132IGSVRSSSPILSEEEPhosphoSitePlus;curated22135298; 23712012; 21630457; 22276854
136RSSSPILSEEEAEGSPhosphoSitePlus;curated22135298; 23712012; 21630457; 22276854
143SEEEAEGSLRNLTPEPhosphoSitePlus22135298
159DPKKRLGSTGSQPSSPhosphoSitePlus;curated22135298; 23712012; 21630457
160PKKRLGSTGSQPSSEcurated21630457
162KRLGSTGSQPSSEAEPhosphoSitePlus;curated22135298; 23712012; 21630457
165GSTGSQPSSEAEPGPcurated21630457
166STGSQPSSEAEPGPEcurated23712012; 21630457
188LPPKRPLSSSDEGNEPhosphoSitePlus;curated22135298; 23712012; 21630457
189PPKRPLSSSDEGNEGcurated21630457
190PKRPLSSSDEGNEGQcurated23712012; 21630457
284PKPAQRNSNPIIAELPhosphoSitePlus22135298
305GTLLSKPSPPLPPKRPhosphoSitePlus22135298
445LTSPLPVTPPLEGTHcurated23984901
456EGTHRAHSLLFESSDcurated22276854
475DTGTLGRTRSLPITIcurated23984901
Sequence
(Fasta)
MEAIPPLSTL ANSGMEDPFE EAERPSGDPG LVMDSVEAGD TTPPTKRKSK FSGFGKIFKP 60
WKWRKKKSSD KFKETSEVLE RKISMRKPRE ELVKRGVLLE DPEQGGEDSG KLSHAALKNG 120
HTTPIGSVRS SSPILSEEEA EGSLRNLTPE EDPKKRLGST GSQPSSEAEP GPEQASKQPL 180
LPPKRPLSSS DEGNEGQAKE VPAGSAARPV SSTSGSGIET PAATTAATDM TKTLTKSFVA 240
STPAPTPAPR TLPAAPASTN TTATHPAPAK QPPIPPPKPA QRNSNPIIAE LSQAMNSGTL 300
LSKPSPPLPP KRGIPSTSVS SSEPAASATA KTANDQREKT VSLCLEPPLT IPPSSPSPPL 360
PTHIPPEPPR SPLVPAKTFQ MVPEVEFSPS LDRFQDISQQ EDQKKEVPKK IQDQSFGESH 420
IPSRLPPVPL HIRIQQALTS PLPVTPPLEG THRAHSLLFE SSDSFSEDTG TLGRTRSLPI 480
TIEMLKVPDD DEEEQICPFV EDMTSTSATP KLPPCLQEEE KESDSDSEGP IQYRDEEEDD 540
DDDESYQSAL ANRVKRKDTL AMKLSSRPSE PETSLSSWPC KSKEEWNEIR HQIGNTLIRR 600
LSQRPTAEEL EQRNILQREL SIMKPRPLCS MNSVCIRTEV FAKRAKESQS LLGKPSLLGN 660
VTWWCLVYCV WHARNFVQML S 682
Keyword

KW-0009--Actin-binding
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR029984--Phactr4
IPR004018--RPEL_repeat

PROSITE

PS51073--RPEL

Pfam

PF02755--RPEL

Gene Ontology

GO:0005622--C:intracellular
GO:0030027--C:lamellipodium
GO:0004864--F:protein phosphatase inhibitor activity
GO:0071862--F:protein phosphatase type 1 activator activity
GO:0030036--P:actin cytoskeleton organization
GO:0061386--P:closure of optic fissure
GO:0048484--P:enteric nervous system development
GO:2001045--P:negative regulation of integrin-mediated signaling pathway
GO:0001755--P:neural crest cell migration
GO:0001843--P:neural tube closure
GO:0051726--P:regulation of cell cycle
GO:0007266--P:Rho protein signal transduction