dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053758
Uniprot Accession M0R7I0; M0R7I0_RAT;
Genbank Protein ID XP_002729642.1; XP_003754193.1;
Genbank Nucleotide ID XM_002729596.4; XM_003754145.3;
Protein Name Importin subunit alpha
Protein Synonyms/Alias
Gene Name LOC100359600
Gene Synonyms/Alias rCG_63447;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Functions in nuclear protein import.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
62SFPDDATSPLQENRNPhosphoSitePlus;curated22135298; 23712012
Sequence
(Fasta)
MSTNENANST AARLNRFKNK GKDSTEMRRR RIEVNVELRK AKKDDQMLKR RNVSSFPDDA 60
TSPLQENRNN QGTVNWSVED IVKGINSNNL ESQLQATQAA RKLLSREKQP PIDNIIRAGL 120
IPKFVSFLGK TDCSPIQFES AWALTNIASG TSEQTKAVVD GGAIPAFISL LASPHAHISE 180
QAVWALGNIA GDGSVFRDLV IKHGAIDPLL ALLAVPDLSS LACGYLRNLT WTLSNLCRNK 240
NPAPPLDAVE QILPTLVRLL HHNDPEVLAD SCWAISYLTD GPNERIEMVV KKGVVPQLVK 300
LLGATELPIV TPALRAIGNI VTGTDEQTQK VIDAGALAVF PSLLTNPKTN IQKEATWTMS 360
NITAGRQDQI QQVVNHGLVP FLIGVLSKAD FKTQKEAAWA ITNYTSGGTV EQIVYLVHCG 420
IIEPLMNLLS AKDTKIIQVI LDAISNIFQA AEKLGETEKL SIMIEECGGL DKIEALQSHE 480
NESVYKASLN LIEKYFSVEE EEDQNVVPET TSEGFAFQVQ DGAPGTFNF
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR032413--Arm_3
IPR000225--Armadillo
IPR002652--Importin-a_IBB
IPR024931--Importing_su_alpha

PROSITE

PS50176--ARM_REPEAT
PS51214--IBB

Pfam

PF00514--Arm
PF16186--Arm_3
PF01749--IBB

Gene Ontology

GO:0005829--C:cytosol
GO:0005643--C:nuclear pore
GO:0005654--C:nucleoplasm
GO:0008139--F:nuclear localization sequence binding
GO:0008565--F:protein transporter activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0006607--P:NLS-bearing protein import into nucleus