dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053755
Uniprot Accession M0R7C4; M0R7C4_RAT;
Genbank Protein ID NP_001099502.1;
Genbank Nucleotide ID NM_001106032.1;
Protein Name Proteasome subunit beta type
Protein Synonyms/Alias
Gene Name Psmb11
Gene Synonyms/Alias rCG_23402;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
271EVLPEPATPQDARESPhosphoSitePlus22135298
Sequence
(Fasta)
MALQDVCKWQ APDTHGLSLR LPQAGGWAVP RGCDPQTFLQ IYGPRLAHGT TTLAFRFRHG 60
VIAAADTRSS CGSYVACPAS RKVIPVHRHL LGTTSGTSAD CATWYRVLRR ELRLRELREG 120
QLPSVAGTAK LLSAMMSRYR GLDLCVATAL CGWDHSGPAL FYVYSDGTCL QGDVFSVGSG 180
SPYAYGVLDR SYHYDMTVQE AYTLARCAVA HATHRDAYSG GSVDLFHVRE SGWEYISRSD 240
ACVLYRELQE AQGFEQELEA KASEVLPEPA TPQDARESEL SVELEEVTPE DCKIIVKTET 300
M 302
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0539--Nucleus
KW-0645--Protease
KW-0647--Proteasome
KW-1185--Reference proteome
KW-0888--Threonine protease

Interpro

IPR029055--Ntn_hydrolases_N
IPR000243--Pept_T1A_subB
IPR016050--Proteasome_bsu_CS
IPR001353--Proteasome_sua/b
IPR023333--Proteasome_suB-type

PROSITE

PS00854--PROTEASOME_BETA_1
PS51476--PROTEASOME_BETA_2

Pfam

PF00227--Proteasome

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005839--C:proteasome core complex
GO:0004175--F:endopeptidase activity
GO:0004298--F:threonine-type endopeptidase activity
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process