dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053753
Uniprot Accession M0R7A6; M0R7A6_RAT;
Genbank Protein ID XP_006225782.1; XP_006239924.1; XP_008762791.1; XP_008774421.1;
Genbank Nucleotide ID XM_006225720.2; XM_006239862.2; XM_008764569.1; XM_008776199.1;
Protein Name Protein Itsn2
Protein Synonyms/Alias
Gene Name Itsn2
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 11
PositionPeptidesSourceReferences ( PMIDs )
211ASIQKAQSLIDLGSScurated23984901
255KYRQKFNSLDKSMSGPhosphoSitePlus22135298
587EYQNKLIYLVPEKQLPhosphoSitePlus22135298
843KMLSSDKTPSPKKALPhosphoSitePlus22135298
845LSSDKTPSPKKALLPPhosphoSitePlus;curated22135298; 22276854
901QKSAFTRTVSPGSVScurated21630457
903SAFTRTVSPGSVSPIPhosphoSitePlus;curated22135298; 21630457; 23984901
908TVSPGSVSPIHGQGQPhosphoSitePlus;curated22135298; 21630457
987RGEPEALYAAVNKKPcurated22276854
1325QAYIRFCSCQLNGAAcurated23712012
1662MFDRDQFSPDDFLGRPhosphoSitePlus22135298
Sequence
(Fasta)		MMAQFPTAMN GGPNMWAITS EERTKHDKQF DNLKPSGGYI TGDQARTFFL QSGLPAPVLA 60
EIWALSDLNK DGKMDQQEFS IAMKLIKLKL QGQQLPVVLP PIMKQPPMFS PLISARFGMG 120
SMPNLSIHQP LPPVAPITAP LSSATSGTSI PPLMMPAPLV PSVSTSSLPN GTASLIQPLS 180
IPYSSSTLPH ASSYSLMMGG FGGASIQKAQ SLIDLGSSSS TSSTASLSGN SPKTGTSEWA 240
VPQPSRLKYR QKFNSLDKSM SGYLSGFQAR NALLQSNLSQ TQLATIWTLA DIDGDGQLKA 300
EEFILAMHLT DMAKAGQPLP LTLPPELVPP SFRGGKQIDS INGTLPSYQK TQEEEPQKKL 360
PVTFEDKRKA NYERGNMELE KRRQVLMEQQ QREAERKAQK EKEEWERKQR ELQEQEWKKQ 420
LELEKRLEKQ RELERQREEE RRKEIERRES CISFPLMRER EWISVYKDRK GFMAELWKPG 480
SCAAKQELER QRRLEWERIR RQELLNQKNR EQEEIVRLNS KKKSLHLELE AVNGKHQQIS 540
GRLQDVRIRK QTQKTELEVL DKQCDLEIME IKQLQQELQE YQNKLIYLVP EKQLLNERIK 600
NMQLSNTPDS GISLLHKKSS EKEELCQRLK EQLDALEKET ASKLSEMDSF NNQLKCGNMD 660
DSVLQCLLSL LSCLNNLFLL LKELRESYNT QQLALEQLHK IKRDKLKELE RKRLEQIQKK 720
KLEDEAARKA KQGKENLWKE SIRKEEEEKQ KRLQEEKSQD RTQEEERKTE AKQSETARAL 780
VNYRALYPFE ARNHDEMSFN SGDIIQVDEK TVGEPGWLYG SFQGKFGWFP CNYVEKMLSS 840
DKTPSPKKAL LPPAVSLSAT SAAPQPLCSN QPAPVTDYQN VSFSNLNVNT TWQQKSAFTR 900
TVSPGSVSPI HGQGQAVENL KAQALCSWTA KKENHLNFSK HDVITVLEQQ ENWWFGEVHG 960
GRGWFPKSYV KIIPGSEVKR GEPEALYAAV NKKPTSTAYP VGEEYIALYS YSSVEPGDLT 1020
FTEGEELLVT QKDGEWWTGS IGERTGIFPS NYVRPKDQEN VGNASKSGAS NKKPEIAQVT 1080
SAYAASGAEQ LSLAPGQLIL ILKKNSSGWW QGELQARGKK RQKGWFPASH VKLLGPSAER 1140
TTPAFHAVCQ VIAMYDYIAN NEDELNFSKG QLINVMNKDD PDWWQGEING VTGLFPSNYV 1200
KMTTDSDPSQ QWCADLQALD TMQPMERKRQ GYIHELIETE ERYMDDLQLV IEVFQKRMAE 1260
SGFLTEAEMA LIFVNWKELI MSNTKLLKAL RVRKKTGGEK MPVEMMGDIL AAELSHMQAY 1320
IRFCSCQLNG AALLQQKTDE DADFKEFLKK LASDPRCKGM PLSSFLLKPM QRITRYPLLI 1380
RSILENTPQN HVDHSSLKLA LERAEELCSQ VNEGVREKEN SDRLEWIQAH VQCEGLAEQL 1440
IFNSLTNCLG PRKLLYSGKL YKTKSNKELH GFLFNDFLLL TYLVRQFAAS SGFEKLFSSK 1500
SSAQFKMYKT PIFLNEVLVK LPTDPSSDEP VFHISHIDRV YTLRTDNINE RTAWVQKIKA 1560
ASEQYIDTEK KKREKAYQAR SQKTSGIGRL MVHVIEATEL KACKPNGKSN PYCEISMGSQ 1620
SYTTRTLQDT LNPKWNFNCQ FFIKDLYQDV LCLTMFDRDQ FSPDDFLGRT EVPVAKIRTE 1680
QESKGPTTRR LLLHEVPTGE VWVRFDLQLF EQKTLL 1717
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0728--SH3 domain
Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain
PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3
Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9
Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction