dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053750
Uniprot Accession M0R762; M0R762_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Protein Smg1
Protein Synonyms/Alias
Gene Name Smg1
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
3551KTQPDVMSQNAKKLIcurated23984901
3564LIQKNLATSADTPPSPhosphoSitePlus22135298
3565IQKNLATSADTPPSTPhosphoSitePlus;curated22135298; 23984901
3568NLATSADTPPSTIPGPhosphoSitePlus;curated22135298; 23984901
3571TSADTPPSTIPGTGKPhosphoSitePlus22135298
Sequence
(Fasta)
MSRRAPGSRL SSGGGGTKYP RSWNDWQPRT DSASADPDTL KYSSSRDRGV SSSYGLQPSN 60
SAVVSRQRHD DTRGHADIQN DEKGSYCLIY SSKKNKSNRF LWAREMEMVQ WLGALFTLTQ 120
HPSAQNRSRK PNKVTERSMS YSDESRLSNL LRRITREDDR DRRLATVKQL KEFIQQPENK 180
LVLVKQLDNI LAAVHDVLNE SSKLLQELRQ EGACCLGLLC ASLSYEAEKI FKWIFSKFSS 240
SAKDEVKLLY LCATYRALET VGEKKAFSSV MQLVMTSLQS ILENVDTPEL LCKCVKCILL 300
VARCYPHIFS TNFRDTVDIL VGWHIDHTQK PSLTQQVSGW LQSLEPFWVA DLAFSTTLLG 360
QFLEDMEAYA EDLSHVASGE SVDEDVPPPS VSLPKLAALL RVFSTVVRSI GERFSPIRGP 420
PITEAYVTDV LYRVMRCVTA ANQVFFSEAV LTAANECVGV LLGSLDPSMT IHCDMVITYG 480
LDQLENCQTC GTDYIISVLN LLTLIVEQIN TKLPSSFVEK LFIPSSKLLF LRYHKEKEVV 540
AVAHAVYQAV LSLKNIPVLE TAYKLILGEM TCALNNLLHS LQLPDACSEI KHEAFQNHVF 600
NIDNANFVVI FDLSALTTIG NAKNSLIGMW ALSPTVFALL SKNLMIVHSD LAVHFPAIQY 660
AVLYTLYSHC TRHDHFISSS LSSSSPSLFD GAVISTVTTA TKKHFSIILN LLGILLKKDN 720
LNQDTRKLLM TWALEVAVLM KKSETYAPLF SLPSFHKFSK GLLANTLVED VNICLQACSS 780
LHALSSSLPD DLLQRCVDVC RVQLVHSGTR IRQAFGKLLK SIPLDVVLSN NNHTEIQEIS 840
LALRSHMSKA PSNTFHPQDF SDVISFILYG NSHRTGKDNW LERLFYSCQR LDKRDQSTIP 900
RNLLKTDAVL WQWAIWEAAQ FTVLSKLRTP LGRAQDTFQT IEGIIRSLAA HTLNPDQDVS 960
QWTTADNDEG HGSNQLRLVL LLQYLENLEK LMYNAYEGCA NALTSPPKVI RTFFYTNRQT 1020
CQDWLTRIRL SIMRVGLLAG QPAVTVRHGF DLLTEMKTNS LSQGNELEVT IMMVVEALCE 1080
LHCPEAIQGI AVWSSSAVGK NLLWINSVAQ QAEGRFEKSV AYQEHLCAMP GVDCCISSFD 1140
KSDSHIGQCW RNSGSPKHSL KWETTKNVLS KSIDSSPEVI NYLGNKACEC YISIADWAAV 1200
QEWQNAVHDL KRETATSLNL KADFTTIKSL SSFESGEFVE CTEQLELLPG ENINLLAGGS 1260
KEKIDMKKLL PNMLSPDPRE LQKSIEVQLL RSSVFLATAL NHVEQDQKWQ SLTENVVKYL 1320
KQTSRIAIGP LRLSTLTVSQ SLPVLSTLQL YCSSALENTV SNRLSTEDCL IPLFSDALRS 1380
CKQHDVRPWM QALRYTMYQN QLLEKIKEQT VPIRSHLMEL GLTAAKFARK RGNVSLATRL 1440
LAQCSEVQLG KTTTAQDLVQ HFKKLSTQGQ VDEKWGPELD IEKTKLLYTA GQSTHAMEML 1500
SSCAISFCKS AKAEYAVAKS ILTLAKWVQA EWKEISGQLR QVYRAQQQQN LSGLSTLSRN 1560
ILALIELPSA NTVGEEHPRI ESESTVHIGV GEPDFILGQL YHLSSVQAPE VAKSWAALAS 1620
WAYRWGRKVV DNASQGEGVR LLPREKSEVQ NLLPDTITEE EKERIYGILG QAVCRPAGIQ 1680
DEDITLQITE SEDNEDDDMV DVIWRQLISS CPWLSELDEN ATEGVIKVWR KVVDRIFSLY 1740
KLSCSAYFTF LKLNAGQVLL DEDDPRLHLS HRAEQSTDDV IVMATLRLLR LLVKHAGELR 1800
QYLEHGLETT PTAPWRGIIP QLFSRLNHPE VYVRQSICNL LCRVAQDSPH LILYPAIVGT 1860
ISLSSESQAS GNKYSSAIPT LLGNIQGEEL LVSECEGGSP PASQDSNKDE PKSGLNEDQA 1920
MMQDCYSKIV DKLSSANPTM VLQVQMLVAE LRRVTVLWDE LWLGVLLQQH MYVLRRIQQL 1980
EDEVKRVQNN NTLRKEEKIA IMREKHTALM KPIVFALEHV RSITAAPAET PHEKWFQDNY 2040
GDAIDNALEK LKTPSNPAKP GSSWIPFKEI MLSLQQRAQK RASYILRLDE ISPWLAAMTN 2100
TEIALPGEVS ARDTVTIHSV GGTITILPTK TKPKKLLFLG SDGKSYPYLF KGLEDLHLDE 2160
RIMQFLSIVN TMFATINRQE TPRFHARHYS VTPLGTRSGL IQWVDGATPL FGLYKRWQQR 2220
EAALQAQKAQ DSYQTPQNPS IVPRPSELYY SKIGPALKTV GLSLDVSRRD WPLHVMKAVL 2280
EELMEATPPN LLAKELWSSC TTPDEWWRVT QSYARSTAVM SMVGYIIGLG DRHLDNVLID 2340
MTTGEVVHID YNVCFEKGKS LRVPEKVPFR MTQNIETALG VTGVEGVFRL SCEQVLHIMR 2400
RGRETLLTLL EAFVYDPLVD WTAGGEAGFA GAVYGGGGQQ AESKQSKREM EREITRSLFS 2460
SRVAEIKVNW FKNRDEMLVV LPKLDSSLDE YLSLQEQLTD VEKLQGKLLE EIEFLEGAEG 2520
VDHPSRTLQH RYSEHTQLQT QQRAVQEAIQ VKLNEFEQWI THYQAAFNNL EATQLASLLQ 2580
EISTQMDLGP PSYVPATAFL QNAGQAHLIS QCEQLEGEVG TLLQQRRSVL RGCLEQLHHY 2640
ATVALQYPKA IFQKHRIEQW KAWMEELICN TTVERCQELY RKYEMQYAPQ PPPTVCQFIT 2700
ATEMTLQRYA ADINSRLIRQ VERLKQEAVT VPVCEDQLKE IERCIKVFLH ENGEEGSLSL 2760
ASVIISALCT LTRRNLMMEG AASSAGEQLV DLTSRDGAWF LEELCSMSGN VTCLVQLLKQ 2820
CHLVPQDLDI PNPVEASEAV HLANGVYTSL QELNSNFRQI IFPEALRCLM KGECTLESML 2880
HELDSLIEQT TDGVPLQTLV ESLQAYLRNT AMGLEEETHA HYIDVARMLH AQYGELIQPR 2940
NGSVDETPKM SAGQMLLVAF DGMFAQVETA FGLLVEKLNK MEIPVAWRKI DIIREARSTQ 3000
ANFFDDDNHR QVLEEIFFLK RLQTIKEFFR LCGTFSKTLS GSSSLEDQNT VNGPVQIVNV 3060
KTLFRNSCFS EDQMAKPIKA FTADFVRQLL IGLPNQALGL TLCSFISALG VDIIAQVEAK 3120
DFGAESKVSV DDLCKKAVEH NIQVGRFSQL VMNRATVLAS SYDTAWKKHD LVRRLETSIS 3180
SCKTSLQRVQ LHIAMFQWQH EDLLINRPQA MSVTPPRSAI LTSMKKKLHA LSQIETSIGT 3240
VQEKLAALEA SIEQRLKWAG GANPALAPVL QDFEATIAER RNLVLKESQR ANQVTFLCSN 3300
IIHFESLRTR TAEALSLDAA LFELIKRCQQ MCSFASQFNS SVSELELRLL QRVDTTLEHP 3360
IGSSEWLLSA HKQLTQDMST QRAVQTEKEQ QIETVCETIQ SLVDSVKTVL TGHNRQLGDV 3420
KHLLKAMAKD EEAALADAED IPYESSVRQF LAEYKSWQDN IQTVLFTLVQ AMGQVRSQEH 3480
VEMLQEITPT LKELKTQSQS IYNNLVSFAS PLVTDAANEC SSPTSSATYQ PSFAAAVRSN 3540
TGQKTQPDVM SQNAKKLIQK NLATSADTPP STIPGTGKSI ACSPKKAIRD PKTGKAVQER 3600
NSYAVSVWKR VKAKLEGRDV DPNRRMSVAE QVDYVIKEAT NLDNLAQLYE GWTAWV 3657
Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR016024--ARM-type_fold
IPR003152--FATC_dom
IPR011009--Kinase-like_dom
IPR000403--PI3/4_kinase_cat_dom
IPR018936--PI3/4_kinase_CS
IPR014009--PIK_FAT
IPR031559--SMG1

PROSITE

PS51189--FAT
PS51190--FATC
PS00916--PI3_4_KINASE_2
PS50290--PI3_4_KINASE_3

Pfam

PF02260--FATC
PF00454--PI3_PI4_kinase
PF15785--SMG1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0016301--F:kinase activity
GO:0016773--F:phosphotransferase activity, alcohol group as acceptor
GO:0044822--F:poly(A) RNA binding
GO:0018105--P:peptidyl-serine phosphorylation
GO:0046854--P:phosphatidylinositol phosphorylation
GO:0046777--P:protein autophosphorylation
GO:0006950--P:response to stress