dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053748
Uniprot Accession M0R757; M0R757_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Elongation factor 1-alpha
Protein Synonyms/Alias
Gene Name LOC100360413
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
23VDSGKSTTTGHLIYKPhosphoSitePlus22135298
24DSGKSTTTGHLIYKCPhosphoSitePlus22135298
29TTTGHLIYKCGGIDKPhosphoSitePlus;curated22135298; 25532521
Sequence
(Fasta)		MGKEKTHINI VVIGHVDSGK STTTGHLIYK CGGIDKRTIE KFEKEAAEMG KGSLKYAWVL 60
DKLKAERERG ITIDISLWKF ETSKYYVTII DAPGHRDFIK NMITGTSQAD CAVLIVAAGV 120
GEFEAGISKN GQTREHALLA YTLGVKQLIV GVNKMDSTEP PYSQKRYEEI VKEVSTYIKK 180
IGYNPDTVAF VPISGWNGDN MLEPSANMPW FKGWKVTRKD GSASGTTLLE ALDCILPPTR 240
PTDKPLRLPL QDVYKIGGIG TVPVGRVETG VLKPGMVVTF APVNVTTEVK SVEMHHEALS 300
EALPGDNVGF NVKNVSVKDV RRGNVAGDSK NDPPMEVAGF TAQVIILNHP GQISAGYAPV 360
LDCHTAHIAC KFAELKEKID RRSGKKLEDG PKFLKSGDAA IVDMVPGKPM CVESFSDYPP 420
LGRFAVRDMR QTVAVGVIKA VDKKAAGAGK VTKSAQKAQK AK 463
Keyword

KW-0181--Complete proteome
KW-0251--Elongation factor
KW-0342--GTP-binding
KW-0547--Nucleotide-binding
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
Interpro

IPR031157--G_TR_CS
IPR027417--P-loop_NTPase
IPR000795--TF_GTP-bd_dom
IPR009000--Transl_B-barrel
IPR009001--Transl_elong_EF1A/Init_IF2_C
IPR004539--Transl_elong_EF1A_euk/arc
IPR004161--Transl_elong_EFTu/EF1A_2
IPR004160--Transl_elong_EFTu/EF1A_C
PROSITE

PS00301--G_TR_1
PS51722--G_TR_2
Pfam

PF03144--GTP_EFTU_D2
PF03143--GTP_EFTU_D3
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005622--C:intracellular
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0003746--F:translation elongation factor activity
GO:0006414--P:translational elongation