dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053724
Uniprot Accession M0R671; M0R671_RAT;
Genbank Protein ID XP_008764088.1; XP_008764089.1; XP_008764090.1;
Genbank Nucleotide ID XM_008765866.1; XM_008765867.1; XM_008765868.1;
Protein Name Protein Tns2
Protein Synonyms/Alias
Gene Name Tns2
Gene Synonyms/Alias Tenc1;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 20
PositionPeptidesSourceReferences ( PMIDs )
102RRIEHLGSTKSLNHSPhosphoSitePlus22135298
120STLPRSFSLDPLMERPhosphoSitePlus;curated22135298; 23984901
179KYLLFNLSEKRHDLTcurated23984901
455EPAVRWDSYENFNQHPhosphoSitePlus22135298
466FNQHHEDSVDGSLAHPhosphoSitePlus22135298
481TRGPLDGSPYAQVQRPhosphoSitePlus22135298
483GPLDGSPYAQVQRVPPhosphoSitePlus;curated22135298; 22817900; 23984901
646EKRRLCRSLSEGPYPcurated23984901
648RRLCRSLSEGPYPYAPhosphoSitePlus22135298
825YPSPGAHSPQAGSVSPhosphoSitePlus;curated22135298; 24945867
830AHSPQAGSVSPGSPPcurated24945867
832SPQAGSVSPGSPPYLPhosphoSitePlus22135298
835AGSVSPGSPPYLQSRPhosphoSitePlus22135298
931RRQDTTRSPSLAPTQcurated23984901
941LAPTQRLSPGEALPSPhosphoSitePlus22135298
991NGWPQERSPGGHTNScurated24945867
1000GGHTNSASPRSPVPTcurated24945867
1003TNSASPRSPVPTTLPPhosphoSitePlus;curated22135298; 22817900; 24945867
1082EKRHLPGSGQQSSPPcurated24945867
1087PGSGQQSSPPARGTNPhosphoSitePlus;curated22135298; 22817900
Sequence
(Fasta)
MKSSGPVERL LRALGRRDSS RATSRPRKAE PHSFREKVFR KKAPVCAVCK VTIDGTGVSC 60
RVCKVATHRK CEAKVTSSCQ ALPPAELRRN TAPVRRIEHL GSTKSLNHSK QRSTLPRSFS 120
LDPLMERRWD LDLTYVTERI LAAAFPARPD EQRHRGHLRE LAHVLQSKHR DKYLLFNLSE 180
KRHDLTRLNP KVHDFGWPEL HAPPLDKLCS ICKAMETWLS ADPQHVVVLY CKGSKGKLGV 240
IVSAYMHYSK ISAGADQALA TLTMRKFCED KAAMELQPSQ HRYVGYFSGL LSGSIRMNSS 300
PLFLHYVFVP VLPAFEPNTG FQPFLKIYQS MQLVYTSGVY HITGPGPRQI CISLEPALLL 360
KGDVMVTCYH KGGQGTDRTL VFRVQFHTCT IHGPRLNFPK DQLDEAWADE RFPFQASVEF 420
VFSSSPEKVK GNTPRNDPSV SVDYNMTEPA VRWDSYENFN QHHEDSVDGS LAHTRGPLDG 480
SPYAQVQRVP RQTPPAPSPE LPPPPMLSVS SDSGHSSTLT TEHTAESPGR PPPTAAERQE 540
LDRLLGGCGV ASAGRGAGRE TAILDDEEQP SVGGGLHLGM YPGHRPGLSR RCSCRQGLRE 600
PCGVPNGGYY RPEGTLERRR PPYGGYEGHP QGYTEASVEK RRLCRSLSEG PYPYAPELGK 660
PANGDFGYRP AGYREVVILE DPGVPALCSC PACEEKMALP TAALYGLRLE REAGEGWSSE 720
VGKPLLHPVR PGHPLPLLVP ACGHHHAPVP DYGCLKSPKV GEEGHEGCSY AVCPEGRYGH 780
PGYPALVTYG YGGAVPSYCP AYGRAPHSCG SPSEGRGYPS PGAHSPQAGS VSPGSPPYLQ 840
SRKLGYEAPA EDGRDKYSLP GPLASAGPLA STESPEPSWR DGSSGHSTLP RSPRDAQCSA 900
SSELSGPSTP LHTSSPVQGK ESTRRQDTTR SPSLAPTQRL SPGEALPSVV QGVTEKTPEL 960
LASSRPEPLD PSPFSQTSTP SSPNGWPQER SPGGHTNSAS PRSPVPTTLP GLRHAPWQGP 1020
QGPSDSPDGS PLTPVPTQMP WLVGSPEPPQ SSPTPAFPLA TSYETNGPTQ PPLPEKRHLP 1080
GSGQQSSPPA RGTNQHVTFA SPLPDVTQPP EHPLQENQSS VKFVQDTSKF WYKPHLSRDQ 1140
AIALLKDKDP GAFLIRDSHS FQGAYGLALK VATPPPSAQP WKGDPSEQLV RHFLIETGPK 1200
GVKIKGCPTE PYFGSLSALV SQHSISPISL PCCLRIPSKD PLEETSEAPV PTNMSTAADL 1260
LRQGAACSVL YLTSVETESL TGPQAVARAS SAALSCSPVP VPAIVHFKVS AQGITLTDNQ 1320
RKVFFRRHYP VNSITFSSTD PQDRRWTNPD GTTSKIFGFV AKKPGSPWEN VCHLFAELDP 1380
DQPASAIVTF ITKVLLGQRK 1401
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0862--Zinc

Interpro

IPR000008--C2_dom
IPR002219--PE/DAG-bd
IPR011993--PH/PTB_dom
IPR029021--Prot-tyrosine_phosphatase-like
IPR013625--PTB
IPR006020--PTB/PI_dom
IPR000980--SH2
IPR014020--Tensin_C2-dom
IPR029023--Tensin_lipid_phosphatase_dom

PROSITE

PS51182--C2_TENSIN
PS51181--PPASE_TENSIN
PS50001--SH2
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF08416--PTB
PF10409--PTEN_C2
PF00017--SH2

Gene Ontology

GO:0005925--C:focal adhesion
GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0019725--P:cellular homeostasis
GO:0032963--P:collagen metabolic process
GO:0035556--P:intracellular signal transduction
GO:0001822--P:kidney development
GO:0035264--P:multicellular organism growth
GO:0048871--P:multicellular organismal homeostasis
GO:0008285--P:negative regulation of cell proliferation
GO:0014850--P:response to muscle activity