| Tag |
Content |
| dbPAF ID |
dbPAF-0053721 |
| Uniprot Accession |
M0R623; M0R623_RAT;
|
| Genbank Protein ID |
NP_446141.3;
|
| Genbank Nucleotide ID |
NM_053689.3;
|
| Protein Name |
Nucleolar GTP-binding protein 1 |
| Protein Synonyms/Alias |
|
| Gene Name |
Gtpbp4 |
| Gene Synonyms/Alias |
|
| Organism |
Rattus norvegicus(Rat) |
| NCBI Taxa ID |
10116 |
Functional Description
(View all) |
Involved in the biogenesis of the 60S ribosomal subunit.Functional Description
Involved in the biogenesis of the 60S ribosomal subunit. |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MAHYNFKKIT VVPSAKDFID LTLSKTQRKT PTVIHKHYQI HRIRHFYMRK VKFTQQNYHD 60
RLSQILSDFP KLDDIHPFYA DLMNILYDKD HYKLALGQIN IAKNLVDNVA KDYVRLMKYG 120
DSLYRCKQLK RAALGRMCTI IKRQRQSLEY LEQVRQHLSR LPTIDPNTRT LLLCGYPNVG 180
KSSFINKVTR ADVDVQPYAF TTKSLFVGHM DYKYLRWQVV DTPGISDHPL EDRNTIEMQA 240
ITALAQPRAA VLYVMDLSEQ CGHGLKEQLE LFQNIRPLFI NKPLIVVANK CDVKRIAELS 300
EEDQKIFLDL QAEGFPVIET STLTEEGVIQ VKTEACDRLL AHRVETKMKG NKVNEVLNRL 360
HLAVPNKRDD KERPPFIPEG VVARRKRMEI AEPKKKRERD LELEMGDDYI LDLQKYWDLM 420
NSSEKYDKIP EIWEGHNVAD YIDPAIMKKL EELEKEEELR TAAGEYDSES ESEDEEMVEI 480
RQLAKQIREK KKLKILQSKE KNTQGPRMPR TAKKVQRADL ENEMRSLGVD MDDKDNAHYA 540
VQARRSRSVT RKRKREESVP PSSIARSRSR SCSKTPRDVS GLRDVKMVKK AKTMMKKAQK 600
KMNRLGKKGE ADRHVFDMKP KHLLSGKRKA GKKDRR
637Fasta Sequence
>M0R623|Gtpbp4|Rattus norvegicus(Rat)
MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHDRLSQILSDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYGDSLYRCKQLKRAALGRMCTIIKRQRQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDVQPYAFTTKSLFVGHMDYKYLRWQVVDTPGISDHPLEDRNTIEMQAITALAQPRAAVLYVMDLSEQCGHGLKEQLELFQNIRPLFINKPLIVVANKCDVKRIAELSEEDQKIFLDLQAEGFPVIETSTLTEEGVIQVKTEACDRLLAHRVETKMKGNKVNEVLNRLHLAVPNKRDDKERPPFIPEGVVARRKRMEIAEPKKKRERDLELEMGDDYILDLQKYWDLMNSSEKYDKIPEIWEGHNVADYIDPAIMKKLEELEKEEELRTAAGEYDSESESEDEEMVEIRQLAKQIREKKKLKILQSKEKNTQGPRMPRTAKKVQRADLENEMRSLGVDMDDKDNAHYAVQARRSRSVTRKRKREESVPPSSIARSRSRSCSKTPRDVSGLRDVKMVKKAKTMMKKAQKKMNRLGKKGEADRHVFDMKPKHLLSGKRKAGKKDRR
|
| Keyword |
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0690--Ribosome biogenesis
|
| Interpro |
IPR031167--G_OBG
IPR006073--GTP_binding_domain
IPR024926--NOG1
IPR010674--NOG1_Rossman_fold_dom
IPR012973--NOG_C
IPR027417--P-loop_NTPase
IPR005225--Small_GTP-bd_dom
|
| PROSITE |
PS51710--G_OBG
|
| Pfam |
PF06858--NOG1
PF08155--NOGCT
|
| Gene Ontology |
GO:0005794--C:Golgi apparatus
GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0044822--F:poly(A) RNA binding
GO:0030336--P:negative regulation of cell migration
GO:0008285--P:negative regulation of cell proliferation
GO:0022408--P:negative regulation of cell-cell adhesion
GO:0033342--P:negative regulation of collagen binding
GO:0008156--P:negative regulation of DNA replication
GO:0031397--P:negative regulation of protein ubiquitination
GO:0001649--P:osteoblast differentiation
GO:0050821--P:protein stabilization
GO:0000079--P:regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0042254--P:ribosome biogenesis
|
