dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053690
Uniprot Accession M0R484; M0R484_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Protein Afap1l2
Protein Synonyms/Alias
Gene Name Afap1l2
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 12
PositionPeptidesSourceReferences ( PMIDs )
54SSSSDEEYIYMNKVAcurated21630457
56SSDEEYIYMNKVAVNcurated21630457
70NKEQNPASPDKVPEEPhosphoSitePlus;curated22135298; 23712012; 21630457
345MNLGRKKSTSLEPPDPhosphoSitePlus;curated22135298; 23712012; 21630457
347LGRKKSTSLEPPDRScurated23712012; 21630457
409CDVLPDPSPDHLYSFcurated21630457
414DPSPDHLYSFRILHNPhosphoSitePlus;curated22135298; 23712012; 21630457
415PSPDHLYSFRILHNGcurated23712012; 21630457
485LLMQRKFSEPNTYIDPhosphoSitePlus22135298
548DRVYLDLTPVKSFLHPhosphoSitePlus22135298
650TMASVPISASPPVKDcurated21630457
652ASVPISASPPVKDKLcurated23712012; 21630457
Sequence
(Fasta)		MERYKALEQL LTELDDFLKV LDQENLSSAA VVKKSGLSEL LRLYTKSSSS DEEYIYMNKV 60
AVNKEQNPAS PDKVPEEKQG PLTNGEPSQH TSAPQKSLPD LPPPKMIPER KQPTIPKIES 120
PEGYYEEAEP FDTSINEDGE AVSSSYESYD EEESSKGKTA PYQWPSPEAS IELMRDARIC 180
AFLWRKKWLG QWAKQLCVIR DTRLLCYKSS KDHSPQLDVN LLGSSVVHKE KQVRKKEHKL 240
KIMPMNADVI VLGLQSKDQA EQWLRVIQEV SGLPSEGASE GNQYTPDAQR LNCQKPDIAE 300
KYMSASEYGI TTDGHPEIPE TRDVKKKCSA GLKLSNLMNL GRKKSTSLEP PDRSLETSSY 360
LNVLVNSQWK SRWCFVRDSH LHFYQDRNRG KMAQQPLSLV GCDVLPDPSP DHLYSFRILH 420
NGEELAKLEA KSSEEMGHWL GLLLSESGSK TDPEELTYDY VDAERVSCIV SAAKTSLLLM 480
QRKFSEPNTY IDGLPSRDCQ EELYDDVEMS ELMAAVEPAE EATLAGDATP AVDANSGSDL 540
DRVYLDLTPV KSFLHNTSEV QVQASLPAVP HLDDVAETLT VDPKPGTTPE EPCTESPGGQ 600
EMQQRQPEGQ EPSEPIEPTP RVTTVKLQAE QQRISFPANC PDTMASVPIS ASPPVKDKLR 660
VTSAEIKLGK NRTEAEVKRY TEEKRRLERS KEEIRGHLAQ LRREKRELKE TLLRCTDKGV 720
VAKLEQALKR IDEECRLEES RRVDLELSIV EVKDNLKKAE AGPVTLGTTV DTTHLDNMSP 780
RPQPKAATPT STPDSTPVNS ASVLKNRPLS VMVTGKGTVL QKAKEWEKKG AS 833
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR030113--AFAP
IPR030115--AFAP1L2
IPR011993--PH/PTB_dom
IPR001849--PH_domain
PROSITE

PS50003--PH_DOMAIN
Pfam

PF00169--PH
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0030296--F:protein tyrosine kinase activator activity
GO:0035591--F:signaling adaptor activity
GO:0006954--P:inflammatory response
GO:0045742--P:positive regulation of epidermal growth factor receptor signaling pathway
GO:0032757--P:positive regulation of interleukin-8 production
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0032675--P:regulation of interleukin-6 production
GO:0007346--P:regulation of mitotic cell cycle