| Tag |
Content |
| dbPAF ID |
dbPAF-0053664 |
| Uniprot Accession |
M0R2B7; M0R2B7_HUMAN;
|
| Genbank Protein ID |
NP_001295561.1;
|
| Genbank Nucleotide ID |
NM_001308632.1;
|
| Protein Name |
DNA polymerase |
| Protein Synonyms/Alias |
|
| Gene Name |
POLD1 |
| Gene Synonyms/Alias |
|
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MDGKRRPGPG PGVPPKRARG GLWDDDDAPR PSQFEEDLAL MEEMEAEHRL QEQEEEELQS 60
VLEGVADGQV PPSAIDPRWL RPTPPALDPQ TEPLIFQQLE IDHYVGPAQP VPGGPPPSRG 120
SVPVLRAFGV TDEGFSVCCH IHGFAPYFYT PAPPGFGPEH MGDLQRELNL AISRDSRGGR 180
ELTGPAVLAV ELCSRESMFG YHGHGPSPFL RITVALPRLV APARRLLEQG IRVAGLGTPS 240
FAPYEANVDF EIRFMVDTDI VGCNWLELPA GKYALRLKEK ATQCQLEADV LWSDVVSHPP 300
EGPWQRIAPL RVLSFDIECA GRKGIFPEPE RDPVIQICSL GLRWGEPEPF LRLALTLRPC 360
APILGAKVQS YEKEEDLLQA WSTFIRIMDP DVITGYNIQN FDLPYLISRA QTLKVQTFPF 420
LGRVAGLCSN IRDSSFQSKQ TGRRDTKVVS MVGRVQMDML QVLLREYKLR SYTLNAVSFH 480
FLGEQKEDVQ HSIITDLQNG NDQTRRRLAV YCLKDAYLPL RLLERLMVLV NAVEMARVTG 540
VPLSYLLSRG QQVKVVSQLL RQAMHEGLLM PVVKSEGGED YTGATVIEPL KGVRPQDRAG 600
AAWELLALTP GRGCSPPRYY DVPIATLDFS SLYPSIMMAH NLCYTTLLRP GTAQKLGLTE 660
DQFIRTPTGD EFVKTSVRKG LLPQILENLL SARKRAKAEL AKETDPLRRQ VLDGRQLALK 720
VSANSVYGFT GAQVGKLPCL EISQSVTGFG RQMIEKTKQL VESKYTVENG YSTSAKVVYG 780
DTDSVMCRFG VSSVAEAMAL GREAADWVSG HFPSPIRLEF EKVYFPYLLI SKKRYAGLLF 840
SSRPDAHDRM DCKGLEAVRR DNCPLVANLV TASLRRLLID RDPEGAVAHA QDVISDLLCN 900
RIDISQLVIT KELTRAASDY AGKQAHVELA ERMRKRDPGS APSLGDRVPY VIISAAKGVA 960
AYMKSEDPLF VLEHSLPIDT QYYLEQQLAK PLLRIFEPIL GEGRAEAVLL RGDHTRCKTV 1020
LTGKVGGLLA FAKRRNCCIG CRTVLSHQGA VCEFCQPRES ELYQKEVSHL NALEERFSRL 1080
WTQCQRCQGS LHEDVICTSR DCPIFYMRKK VRKDLEDQEQ LLRRFGPPGP EAW
1134Fasta Sequence
>M0R2B7|POLD1|Homo sapiens(Human)
MDGKRRPGPGPGVPPKRARGGLWDDDDAPRPSQFEEDLALMEEMEAEHRLQEQEEEELQSVLEGVADGQVPPSAIDPRWLRPTPPALDPQTEPLIFQQLEIDHYVGPAQPVPGGPPPSRGSVPVLRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGPEHMGDLQRELNLAISRDSRGGRELTGPAVLAVELCSRESMFGYHGHGPSPFLRITVALPRLVAPARRLLEQGIRVAGLGTPSFAPYEANVDFEIRFMVDTDIVGCNWLELPAGKYALRLKEKATQCQLEADVLWSDVVSHPPEGPWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEKEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPFLGRVAGLCSNIRDSSFQSKQTGRRDTKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNDQTRRRLAVYCLKDAYLPLRLLERLMVLVNAVEMARVTGVPLSYLLSRGQQVKVVSQLLRQAMHEGLLMPVVKSEGGEDYTGATVIEPLKGVRPQDRAGAAWELLALTPGRGCSPPRYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPGTAQKLGLTEDQFIRTPTGDEFVKTSVRKGLLPQILENLLSARKRAKAELAKETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVISDLLCNRIDISQLVITKELTRAASDYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVLSHQGAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQEQLLRRFGPPGPEAW
|
| Keyword |
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0235--DNA replication
KW-0238--DNA-binding
KW-0239--DNA-directed DNA polymerase
KW-0548--Nucleotidyltransferase
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase
|
| Interpro |
IPR006172--DNA-dir_DNA_pol_B
IPR017964--DNA-dir_DNA_pol_B_CS
IPR006133--DNA-dir_DNA_pol_B_exonuc
IPR006134--DNA-dir_DNA_pol_B_multi_dom
IPR023211--DNA_pol_palm_dom
IPR012337--RNaseH-like_dom
IPR025687--Znf-C4pol
|
| PROSITE |
PS00116--DNA_POLYMERASE_B
|
| Pfam |
PF00136--DNA_pol_B
PF03104--DNA_pol_B_exo1
PF14260--zf-C4pol
|
| Gene Ontology |
GO:0016235--C:aggresome
GO:0005737--C:cytoplasm
GO:0043625--C:delta DNA polymerase complex
GO:0005654--C:nucleoplasm
GO:0008296--F:3'-5'-exodeoxyribonuclease activity
GO:0003677--F:DNA binding
GO:0003887--F:DNA-directed DNA polymerase activity
GO:0000166--F:nucleotide binding
GO:0045004--P:DNA replication proofreading
GO:0006261--P:DNA-dependent DNA replication
GO:0090305--P:nucleic acid phosphodiester bond hydrolysis
|
