dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053615
Uniprot Accession L7N466; L7N466_MOUSE;
Genbank Protein ID NP_001122073.1;
Genbank Nucleotide ID NM_001128601.1;
Protein Name 5-formyltetrahydrofolate cyclo-ligase
Protein Synonyms/Alias
Gene Name Mthfsl
Gene Synonyms/Alias Gm2382;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
8MAAVTVNSAKRGLRAcurated25266776; 23984901; 25338131
Sequence
(Fasta)
MAAVTVNSAK RGLRAELKQR LRALSAEERL RQSLLLTQKV IAHNQYQNSK RISIFLSMQD 60
EVETEVIIKD IFKQGKICFI PQYQFQSNHM DMVRLTSPEE IALLPKTSWN IHQPGEGDVR 120
EEALSTGGLD LIFLPGLGFD KDGNRLGRGK GYYDTYLKRC VQHQEVKPYT MALAFKEQIC 180
PQIPVDEHDM KVDEVLYEDS PAS 204
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR002698--FTHF_cligase
IPR024185--FTHF_cligase-like

PROSITE
Pfam

PF01812--5-FTHF_cyc-lig

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005759--C:mitochondrial matrix
GO:0005739--C:mitochondrion
GO:0030272--F:5-formyltetrahydrofolate cyclo-ligase activity
GO:0005524--F:ATP binding
GO:0005542--F:folic acid binding
GO:0046872--F:metal ion binding
GO:0009396--P:folic acid-containing compound biosynthetic process
GO:0035999--P:tetrahydrofolate interconversion