dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053614
Uniprot Accession L7N463; L7N463_MOUSE;
Genbank Protein ID NP_663449.2;
Genbank Nucleotide ID NM_145474.2;
Protein Name Protein Cyp2d34
Protein Synonyms/Alias
Gene Name Cyp2d34
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
138WREQRQFSVSTLRNFPhosphoSitePlus;curated22135298; 21743459
382LNIPRITSRDIEVQDcurated23984901
493IPVAPYPYQVCAIMRPhosphoSitePlus22135298
Sequence
(Fasta)
MELLTGTGLW SVAIFTVIFL ILVDLMHRRQ HWTSRYPPGP VPWPVLGNLL QVDLDNIPYS 60
LYKLQNRYGD VFSLQMAWKP VVVINGLKAM QEVLLTCGKD TADHPPVPIF EYLGFKSKSQ 120
GVVLASYGPE WREQRQFSVS TLRNFGLGKK SLEEWVTKEA KHLCDAFTAR AGQSINPNTM 180
LNNAVCNVIA SLIFARRFEY EDPFLIRMLK MREESLKEVT GFIPGVLNTF PILLRIPGLA 240
DMVFQSQKTF MAILDNLVTE NRTTWDPDQP PRNLADAFLA EIQKAKGNPE SSFNDENLCM 300
VVSDLFTAGM VTTSTTLSCA LLLMILHPDV QRRVQQEIDA VIGQVRCPEM ADQARMPYTN 360
AVIHEVQRFG DIIPLNIPRI TSRDIEVQDF LIPKGTILIP NMSSMLKDET VWEKPLRFYP 420
EHFLDAQGHF VKPEAFMPFS AGRRSCLGEP LARMELFLFF TCLLQRFSFS VPAGQPQPSD 480
HRIFAIPVAP YPYQVCAIMR EQGH 505
Keyword

KW-0181--Complete proteome
KW-0349--Heme
KW-0408--Iron
KW-0472--Membrane
KW-0479--Metal-binding
KW-0503--Monooxygenase
KW-0560--Oxidoreductase
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001128--Cyt_P450
IPR017972--Cyt_P450_CS
IPR002401--Cyt_P450_E_grp-I
IPR008069--Cyt_P450_E_grp-I_CYP2D-like

PROSITE

PS00086--CYTOCHROME_P450

Pfam

PF00067--p450

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0043231--C:intracellular membrane-bounded organelle
GO:0008392--F:arachidonic acid epoxygenase activity
GO:0020037--F:heme binding
GO:0005506--F:iron ion binding
GO:0016712--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0019825--F:oxygen binding
GO:0008395--F:steroid hydroxylase activity
GO:0019369--P:arachidonic acid metabolic process
GO:0042738--P:exogenous drug catabolic process
GO:0055114--P:oxidation-reduction process
GO:0006805--P:xenobiotic metabolic process