dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053585
Uniprot Accession K9M1U5; IFNL4_HUMAN; K9M1A5; K9M269; K9M2P7;
Genbank Protein ID NP_001263183.2;
Genbank Nucleotide ID NM_001276254.2;
Protein Name Interferon lambda-4
Protein Synonyms/Alias
Gene Name IFNL4
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Cytokine that may trigger an antiviral response activating the JAK-STAT pathway and up-regulating specifically some interferon-stimulated genes.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
131ELARPGSSRKVPGAQcurated20363803
Sequence
(Fasta)		MRPSVWAAVA AGLWVLCTVI AAAPRRCLLS HYRSLEPRTL AAAKALRDRY EEEALSWGQR 60
NCSFRPRRDP PRPSSCARLR HVARGIADAQ AVLSGLHRSE LLPGAGPILE LLAAAGRDVA 120
ACLELARPGS SRKVPGAQKR RHKPRRADSP RCRKASVVFN LLRLLTWELR LAAHSGPCL 180
Keyword

KW-0025--Alternative splicing
KW-0051--Antiviral defense
KW-0181--Complete proteome
KW-0202--Cytokine
KW-0963--Cytoplasm
KW-1185--Reference proteome
KW-0964--Secreted
KW-0732--Signal
Interpro

IPR029177--INF_lambda
PROSITE
Pfam

PF15177--IL28A
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005615--C:extracellular space
GO:0005125--F:cytokine activity
GO:0051607--P:defense response to virus
GO:0050778--P:positive regulation of immune response
GO:0042508--P:tyrosine phosphorylation of Stat1 protein
GO:0042502--P:tyrosine phosphorylation of Stat2 protein