dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053502
Uniprot Accession K7EKF7; K7EKF7_HUMAN;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Voltage-dependent P/Q-type calcium channel subunit alpha-1A
Protein Synonyms/Alias
Gene Name CACNA1A
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
790PAENQTISDTSPMKRcurated25627689
792ENQTISDTSPMKRSAcurated25627689
793NQTISDTSPMKRSAScurated25627689
Sequence
(Fasta)
LDFIVVSGAL VAFAFTGNSK GKDINTIKSL RVLRVLRPLK TIKRLPKLKA VFDCVVNSLK 60
NVFNILIVYM LFMFIFAVVA VQLFKGKFFH CTDESKEFEK DCRGKYLLYE KNEVKARDRE 120
WKKYEFHYDN VLWALLTLFT VSTGEGWPQV LKHSVDATFE NQGPSPGYRM EMSIFYVVYF 180
VVFPFFFVNI FVALIIITFQ EQGDKMMEEY SLEKNERACI DFAISAKPLT RHMPQNKQSF 240
QYRMWQFVVS PPFEYTIMAM IALNTIVLMM KFYGASVAYE NALRVFNIVF TSLFSLECVL 300
KVMAFGILNY FRDAWNIFDF VTVLGSITDI LVTEFGNNFI NLSFLRLFRA ARLIKLLRQG 360
YTIRILLWTF VQSFKALPYV CLLIAMLFFI YAIIGMQVFG NIGIDVEDED SDEDEFQITE 420
HNNFRTFFQA LMLLFRSATG EAWHNIMLSC LSGKPCDKNS GILTRECGNE FAYFYFVSFI 480
FLCSFLMLNL FVAVIMDNFE YLTRDSSILG PHHLDEYVRV WAEYDPAAWG RMPYLDMYQM 540
LRHMSPPLGL GKKCPARVAY KRLLRMDLPV ADDNTVHFNS TLMALIRTAL DIKIAKGGAD 600
KQQMDAELRK EMMAIWPNLS QKTLDLLVTP HKSTDLTVGK IYAAMMIMEY YRQSKAKKLQ 660
AMREEQDRTP LMFQRMEPPS PTQEGGPGQN ALPSTQLDPG GALMAHESGL KESPSWVTQR 720
AQEMFQKTGT WSPEQGPPTD MPNSQPNSQS VEMREMGRDG YSDSEHYLPM EGQGRAASMP 780
RLPAENQTIS DTSPMKRSAS VLGPKARRLD DYSLERVPPE ENQRHHQRRR DRSHRASERS 840
LGRYTDVDTG LGTDLSMTTQ SGDLPSKERD QERGRPKDRK HRQHHHHHHH HHHPPPPDKD 900
RYAQERPDHG RARARDQRWS RSPSEGREHM AHRQGSSSVS GSPAPSTSGT STPRRGRRQL 960
PQTPSTPRPH VSYSPVIRKA GGSGPPQQQQ QQQQQQQQQA VARPGRAATS GPRRYPGPTA 1020
EPLAGDRPPT GGHSSGRSPR MERRVPGPAR SESPRACRHG GARWPASGPH VSEGPPGPRH 1080
HGYYRGSDYD EADGPGSGGG EEAMAGAYDA PPPVRHASSG ATGRSPRTPR ASGPACASPS 1140
RHGRRLPNGY YPAHGLARPR GPGSRKGLHE PYSESDDDWC 1181
Keyword

KW-0181--Complete proteome
KW-0407--Ion channel
KW-0406--Ion transport
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
KW-0851--Voltage-gated channel

Interpro

IPR005448--CACNA1A
IPR027359--Channel_four-helix_dom
IPR031649--GPHH_dom
IPR005821--Ion_trans_dom
IPR014873--VDCC_a1su_IQ

PROSITE
Pfam

PF08763--Ca_chan_IQ
PF16905--GPHH
PF00520--Ion_trans

Gene Ontology

GO:0005891--C:voltage-gated calcium channel complex
GO:0008331--F:high voltage-gated calcium channel activity
GO:0070509--P:calcium ion import
GO:0006816--P:calcium ion transport
GO:0034220--P:ion transmembrane transport
GO:0086010--P:membrane depolarization during action potential
GO:0007268--P:synaptic transmission