dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053500
Uniprot Accession K7EK91; K7EK91_HUMAN;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Dynein heavy chain 17, axonemal
Protein Synonyms/Alias
Gene Name DNAH17
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
1240NKQQKSISAMEGIMEPhosphoSitePlus22135298
1250EGIMEALSKSGGLFEPhosphoSitePlus22135298
Sequence
(Fasta)
MTMAPDVRLE YLEEVASIVL KFKPDKWSKL IGAEENVALF TEFFEKPDVQ VLVLTLNAAG 60
MIIPCLGFPQ SLKSKGVYFI KTKSENINKD NYRARLLYGD ISPTPVDQLI AVVEEVLSSL 120
LNQSENMAGW PQVVSEDIVK QVHRLKNEMF VMSGKIKGKT LLPIPEHLGS LDGTLESMER 180
IPSSLDNLLL HAIETTIIDW SHQIRDVLSK DSAQALLDGL HPLPQVEFEF WDTRLLNLKC 240
IHEQLNRPKV NKIVEILEKA KSCYWPALQN VYTNVTEGLK EANDIVLYLK PLRILLEEME 300
QADFTMLPTF IAKVLDTICF IWATSEYYNT PARIIVILQE FCNQIIEMTR TFLSPEEVLK 360
GLQGEIEEVL SGISLAVNVL KELYQTYDFC CVNMKLFFKD KEPVPWEFPS SLAFSRINSF 420
FQRIQTIEEL YKTAIEFLKL EKIELGGVRG NLLGSLVTRI YDEVFELVKV FADCKYDPLD 480
PGDSNFDRDY ADFEIKIQDL DRRLATIFCQ GFDDCSCIKS SAKLLYMCGG LMERPLILAE 540
VAPRYSVMLE LFDAELDNAK ILYDAQMAAS EEGNIPLIHK NMPPVAGQLK WSLELQERLE 600
VSMKHLKHVE HPVMSGAEAK LTYQKYDEMM ELLRCHREKI YQQWVAGVDQ DCHFNLGQPL 660
ILRDAASNLI HVNFSKALVA VLREVKYLNF QQQKEIPDSA ESLFSENETF RKFVGNLELI 720
VGWYNEIKTI VKAVEFLLIK SELEAIDVKL LSAETTLFWN GEGVFQYIQE VREILHNLQN 780
RMQKAKQNIE GISQAMKDWS ANPLFERKDN KKEALLDLDG RIANLNKRYA AVRDAGVKIQ 840
AMVAENAELF RADTLSLPWK DYVIYIDDMV LDEFDQFIRK SLSFLMDNME SIAPLFEIRM 900
ELDEDGLTFN PTLEVGSDRG FLALIEGLVN DIYNVARLIP RLAKDRMNYK MDLEDNTDLI 960
EMREEVSSLV INAMKEAEEY QDSFERYSYL WTDNLQEFMK NFLIYGCAVT AEDLDTWTDD 1020
TIPKTPPTLA QFQEQIDSYE KLYEEVSKCE NTKVFHGWLQ CDCRPFKQAL LSTIRRWGFM 1080
FKRHLSNHVT NSLADLEAFM KVARMGLTKP LKEGDYDGLV EVMGHLMKVK ERQAATDNMF 1140
EPLKQTIELL KTYGEEMPEE IHLKLQELPE HWANTKKLAI QVKLTVAPLQ ANEVSILRRK 1200
CQQFELKQHE FRERFRREAP FSFSDPNPYK SLNKQQKSIS AMEGIMEALS KSGGLFEVPV 1260
PDYKQLKACH REVRLLKELW DMVVVVNTSI EDWKTTKWKD INVEQMDIDC KKFAKDMRSL 1320
DKEMKTWDAF VGLDNTVKNV ITSLRAVSEL QNPAIRERHW QQLMQATQVK FKMSEETTLA 1380
DLLQLNLHSY EDEVRNIVDK AVKESGMEKV LKALDSTWSM MEFQHEPHPR TGTMMLKSSE 1440
VLVETLEDNQ VQLQNLMMSK YLAHFLKEVT SWQQKLSTAD SVISIWFEVQ RTWSHLESIF 1500
IGSEDIRTQL PGDSQRFDDI NQEFKALMED AVKTPNVVEA TSKPGLYNKL EALKKSLAIC 1560
EKALAEYLET KRLAFPRFYF VSSADLLDIL SNGNDPVEVS RHLSKLFDSL CKLKFRLDAS 1620
DKPLKVGLGM YSKEDEYMVF DQECDLSGQV EVWLNRVLDR MCSTLRHEIP EAVVTYEEKP 1680
REQWILDYPA QVALTCTQIW WTTEVGLAFA RLEEGYENAI RDYNKKQISQ LNVLITLLMG 1740
NLNAGDRMKI MTICTIDVHA RDVVAKMIVV ESSQAFTWQA QLRHRWDEEK RHCFANICDA 1800
QIQYSYEYLG NTPRLVITPL TDRCYITLTQ SLHLIMGGAP AGPAGTGKTE TTKDLGRALG 1860
TMVYVFNCSE QMDYKSCGNI YKGLAQTGAW GCFDEFNRIS VEVLSVIAVQ VKCVQDAIRA 1920
KKKAFNFLGE IIGLIPTVGI FITMNPGYAG RAELPENLKA LFRPCAMVVP DFELICEIML 1980
MAEGFLEARL LARKFITLYT LCKELLSKQD HYDWGLRAIK SVLVVAGSLK RGDPSRAEDQ 2040
VLMRALRDFN IPKIVTDDLP VFMGLIGDLF PALDVPRKRD LNFEKIIKQS IVELKLQAED 2100
SFVLKVVQLE ELLQVRHSVF IVGNAGSGKS QVLKSLNKTY QNLKRKPVAV DLDPKAVTCD 2160
ELFGIINPVT REWKDGLFST IMRDLANITH DGPKWIILDG DIDPMWIESL NTVMDDNKVL 2220
TLASNERIPL NRTMRLVFEI SHLRTATPAT VSRAGILYIN PADLGWNPVV SSWIERRKVQ 2280
SEKANLMILF DKYLPTCLDK LRFGFKKITP VPEITVIQTI LYLLECLLTE KTVPPDSPRE 2340
LYELYFVFTC FWAFGGAMFQ DQLVDYRVEF SKWWINEFKT IKFPSQGTIF DYYIDPDTKK 2400
FLPWTDKVPS FELDPDVPLQ ASLVHTTETI RIRYFMDLLM EKSWPVMLVG NAGTGKSVLM 2460
GDKLESLNTD NYLVQAVPFN FYTTSAMLQG VLEKPLEKKS GRNYGPPGTK KLVYFIDDMN 2520
MPEVDKYGTV APHTLIRQHM DHRHWYDRHK LTLKDIHNCQ YVACMNPTSG SFTIDSRLQR 2580
HFCVFAVSFP GQEALTTIYN TILTQHLAFR SVSMAIQRIS SQLVAAALAL HQKITATFLP 2640
TAIKFHYVFN LRDLSNIFQG LLFSTAEVLK TPLDLVRLWL HETERVYGDK MVDEKDQETL 2700
HRVTMASTKK FFDDLGDELL FAKPNIFCHF AQGIGDPKYV PVTDMAPLNK LLVDVLDSYN 2760
EVNAVMNLVL FEDAVAHICR INRILESPRG NALLVGVGGS GKQSLSRLAA YISGLDVFQI 2820
TLKKGYGIPD LKIDLAAQYI KAAVKNVPSV FLMTDSQVAE EQFLVLINDL LASGEIPGLF 2880
MEDEVENIIS SMRPQVKSLG MNDTRETCWK FFIEKVRRQL KVILCFSPVG SVLRVRARKF 2940
PAVVNCTAID WFHEWPEDAL VSVSARFLEE TEGIPWEVKA SISFFMSYVH TTVNEMSRVY 3000
LATERRYNYT TPKTFLEQIK LYQNLLAKKR TELVAKIERL ENGLMKLQST ASQVDDLKAK 3060
LAIQEAELKQ KNESADQLIQ VVGIEAEKVS KEKAIADQEE VKVEVINKNV TEKQKACETD 3120
LAKAEPALLA AQEALDTLNK NNLTELKSFG SPPDAVVNVT AAVMILTAPG GKIPKDKSWK 3180
AAKIMMGKVD TFLDSLKKFD KEHIPEACLK AFKPYQGNPT FDPEFIRSKS TAAAGLCSWC 3240
INIVRFYEVY CDVAPKRQAL EEANAELAEA QEKLSRIKNK IAELNANLSN LTSAFEKATA 3300
EKIKCQQEAD ATNRVILLAN RLVGGLASEN IRWAESVENF RSQGVTLCGD VLLISAFVSY 3360
VGYFTKKYRN ELMEKFWIPY IHNLKVPIPI TNGLDPLSLL TDDADVATWN NQGLPSDRMS 3420
TENATILGNT ERWPLIVDAQ LQGIKWIKNK YRSELKAIRL GQKSYLDVIE QAISEGDTLL 3480
IENIGETVDP VLDPLLGRNT IKKGKYIKIG DKEVEYHPKF RLILHTKYFN PHYKPEMQAQ 3540
CTLINFLVTR DGLEDQLLAA VVAKERPDLE QLKANLTKSQ NEFKIVLKEL EDSLLARLSA 3600
ASGNFLGDTA LVENLETTKH TASEIEEKVV EAKITEVKIN EARENYRPAA ERASLLYFIL 3660
NDLNKINPVY QFSLKAFNVV FEKAIQRTTP ANEVKQRVIN LTDEITYSVY MYTARGLFER 3720
DKLIFLAQVT FQVLSMKKEL NPVELDFLLR FPFKAGVVSP VDFLQHQGWG GIKALSEMDE 3780
FKNLDSDIEG SAKRWKKLVE SEAPEKEIFP KEWKNKTALQ KLCMVRCLRP DRMTYAIKNF 3840
VEEKMGSKFV EGRSVEFSKS YEESSPSTSI FFILSPGVDP LKDVEALGKK LGFTIDNGKL 3900
HNVSLGQGQE VVAENALDVA AEKGHWVILQ NIHLVARWLG TLDKKLEHYS TGSHEDYRVF 3960
ISAEPAPSPE THIIPQGILE NAIKITNEPP TGMHANLHKA LDLFTQDTLE MCTKEMEFKC 4020
MLFALCYFHA VVAERRKFGA QGWNRSYPFN NGDLTISINV LYNYLEANPK VPWDDLRYLF 4080
GEIMYGGHIT DDWDRRLCRT YLAEYIRTEM LEGDVLLAPG FQIPPNLDYK GYHEYIDENL 4140
PPESPYLYGL HPNAEIGFLT VTSEKLFRTV LEMQPKETDS GAGTGVSREE KVKAVLDDIL 4200
EKIPETFNMA EIMAKAAEKT PYVVVAFQEC ERMNILTNEM RRSLKELNLG LKGELTITTD 4260
VEDLSTALFY DTVPDTWVAR AYPSMMGLAA WYADLLLRIR ELEAWTTDFA LPTTVWLAGF 4320
FNPQSFLTAI MQSMARKNEW PLDKMCLSVE VTKKNREDMT APPREGSYVY GLFMEGARWD 4380
TQTGVIAEAR LKELTPAMPV IFIKAIPVDR METKNIYECP VYKTRIRGPT YVWTFNLKTK 4440
EKAAKWILAA VALLLQV 4458
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR011704--ATPase_dyneun-rel_AAA
IPR026983--DHC_fam
IPR024743--Dynein_HC_stalk
IPR024317--Dynein_heavy_chain_D4_dom
IPR004273--Dynein_heavy_dom
IPR013594--Dynein_heavy_dom-1
IPR013602--Dynein_heavy_dom-2
IPR027417--P-loop_NTPase

PROSITE
Pfam

PF07728--AAA_5
PF12780--AAA_8
PF08385--DHC_N1
PF08393--DHC_N2
PF03028--Dynein_heavy
PF12777--MT

Gene Ontology

GO:0030286--C:dynein complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement