dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053484
Uniprot Accession J3QTB0; J3QTB0_HUMAN;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Short transient receptor potential channel 3
Protein Synonyms/Alias
Gene Name TRPC3
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
11SPSLRRMTVMREKGRHPRD 9;PhosphoSitePlus14983059; 18988627; 22135298
Sequence
(Fasta)
MEGSPSLRRM TVMREKGRRQ AVRGPAFMFN DRGTSLTAEE ERFLDAAEYG NIPVVRKMLE 60
ESKTLNVNCV DYMGQNALQL AVGNEHLEVT ELLLKKENLA RIGDALLLAI SKGYVRIVEA 120
ILNHPGFAAS KRLTLSPCEQ ELQDDDFYAY DEDGTRFSPD ITPIILAAHC QKYEVVHMLL 180
MKGARIERPH DYFCKCGDCM EKQRHDSFSH SRSRINAYKG LASPAYLSLS SEDPVLTALE 240
LSNELAKLAN IEKEFKNDYR KLSMQCKDFV VGVLDLCRDS EEVEAILNGD LESAEPLEVH 300
RHKASLSRVK LAIKYEVKKL GKILRSPFMK FVAHAASFII FLGLLVFNAS DRFEGITTLP 360
NITVTDYPKQ IFRVKTTQFT WTEMLIMVWV LGMMWSECKE LWLEGPREYI LQLWNVLDFG 420
MLSIFIAAFT ARFLAFLQAT KAQQYVDSYV QESDLSEVTL PPEIQYFTYA RDKWLPSDPQ 480
IISEGLYAIA VVLSFSRIAY ILPANESFGP LQISLGRTVK DIFKFMVLFI MVFFAFMIGM 540
FILYSYYLGA KVNAAFTTVE ESFKTLFWSI FGLSEVTSVV LKYDHKFIEN IGYVLYGIYN 600
VTMVVVLLNM LIAMINSSYQ EIEDDSDVEW KFARSKLWLS YFDDGKTLPP PFSLVPSPKS 660
FVYFIMRIVN FPKCRRRRLQ KDIEMGMGNS KSRLNLFTQS NSRVFESHSF NSILNQPTRY 720
QQIMKRLIKR YVLKAQVDKE NDEVNEGELK EIKQDISSLR YELLEDKSQA TEELAILIHK 780
LSEKLNPSML RCE 794
Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-0407--Ion channel
KW-0406--Ion transport
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR005821--Ion_trans_dom
IPR004729--TRP_channel
IPR013555--TRP_dom
IPR005459--TRPC3_channel
IPR002153--TRPC_channel

PROSITE

PS50297--ANK_REP_REGION

Pfam

PF12796--Ank_2
PF00520--Ion_trans
PF08344--TRP_2

Gene Ontology

GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0005262--F:calcium channel activity
GO:0051480--P:cytosolic calcium ion homeostasis
GO:0006828--P:manganese ion transport