dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053481
Uniprot Accession J3QT34; J3QT34_HUMAN;
Genbank Protein ID NP_001158136.1;
Genbank Nucleotide ID NM_001164664.1;
Protein Name Microtubule-associated serine/threonine-protein kinase 4
Protein Synonyms/Alias
Gene Name MAST4
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
213SAPSLTASLKELSLPcurated25849741
266QDSPRNFSPSASAHFcurated25849741
Sequence
(Fasta)
MGEKVSEAPE PVPRGCSGHG SRTPASALVA ASSPGASSAE SSSGSETLSE EGEPGGFSRE 60
HQPPPPPPLG GTLGARAPAA WAPASVLLER GVLALPPPLP GGAVPPAPRG SSASQEEQDE 120
ELDHILSPPP MPFRKCSNPD VASGPGKSLK YKRQLSEDGR QLRRGSLGGA LTGRYLLPNP 180
VAGQAWPASA ETSNLVRMRS QALGQSAPSL TASLKELSLP RRGSFCRTSN RKSLIGNGQS 240
PALPRPHSPL SAHAGNSPQD SPRNFSPSAS AHFSFARRTD GRRWSLASLP SSGYGTNTPS 300
STVSSSCSSQ EKLHQLPYQP TPDELHFLSK HFCTTESIAT ENRCRNTPMR PRSRSLSPGR 360
SPACCDHEII MMNHVYKERF PKATAQMEER LKEIITSYSP DNVLPLADGV LSFTHHQIIE 420
LARDCLDKSH QGLITSRYFL ELQHKLDKLL QEAHDRSESG ELAFIKQLVR KILIVIARPA 480
RLLECLEFDP EEFYYLLEAA EGHAKEGQGI KTDIPRYIIS QLGLNKDPLE EMAHLGNYDS 540
GTAETPETDE SVSSSNASLK LRRKPRESDF ETIKLISNGA YGAVYFVRHK ESRQRFAMKK 600
INKQNLILRN QIQQAFVERD ILTFAENPFV VSMYCSFETR RHLCMVMEYV EGGDCATLMK 660
NMGPLPVDMA RMYFAETVLA LEYLHNYGIV HRDLKPDNLL VTSMGHIKLT DFGLSKVGLM 720
SMTTNLYEGH IEKDAREFLD KQVCGTPEYI APEVILRQGY GKPVDWWAMG IILYEFLVGC 780
VPFFGDTPEE LFGQVISDEI NWPEKDEAPP PDAQDLITLL LRQNPLERLG TGGAYEVKQH 840
RFFRSLDWNS LLRQKAEFIP QLESEDDTSY FDTRSEKYHH METEEEDDTN DEDFNVEIRQ 900
FSSCSHRFSK VFSSIDRITQ NSAEEKEDSV DKTKSTTLPS TETLSWSSEY SEMQQLSTSN 960
SSDTESNRHK LSSGLLPKLA ISTEGEQDEA ASCPGDPHEE PGKPALPPEE CAQEEPEVTT 1020
PASTISSSTL SVGSFSEHLD QINGRSECVD STDNSSKPSS EPASHMARQR LESTEKKKIS 1080
GKVTKSLSAS ALSLMIPGDM FAVSPLGSPM SPHSLSSDPS SSRDSSPSRD SSAASASPHQ 1140
PIVIHSSGKN YGFTIRAIRV YVGDSDIYTV HHIVWNVEEG SPACQAGLKA GDLITHINGE 1200
PVHGLVHTEV IELLLKSGNK VSITTTPFEN TSIKTGPARR NSYKSRMVRR SKKSKKKESL 1260
ERRRSLFKKL AKQPSPLLHT SRSFSCLNRS LSSGESLPGS PTHSLSPRSP TPSYRSTPDF 1320
PSGTNSSQSS SPSSSAPNSP AGSGHIRPST LHGLAPKLGG QRYRSGRRKS AGNIPLSPLA 1380
RTPSPTPQPT SPQRSPSPLL GHSLGNSKIA QAFPSKMHSP PTIVRHIVRP KSAEPPRSPL 1440
LKRVQSEEKL SPSYGSDKKH LCSRKHSLEV TQEEVQREQS QREAPLQSLD ENVCDVPPLS 1500
RARPVEQGCL KRPVSRKVGR QESVDDLDRD KLKAKVVVKK ADGFPEKQES HQKSHGPGSD 1560
LENFALFKLE EREKKVYPKA VERSSTFENK ASMQEAPPLG SLLKDALHKQ ASVRASEGAM 1620
SDGRVPAEHR QGGGDFRRAP APGTLQDGLC HSLDRGISGK GEGTEKSSQA KELLRCEKLD 1680
SKLANIDYLR KKMSLEDKED NLCPVLKPKM TAGSHECLPG NPVRPTGGQQ EPPPASESRA 1740
FVSSTHAAQM SAVSFVPLKA LTGRVDSGTE KPGLVAPESP VRKSPSEYKL EGRSVSCLKP 1800
IEGTLDIALL SGPQASKTEL PSPESAQSPS PSGDVRASVP PVLPSSSGKK NDTTSARELS 1860
PSSLKMNKSY LLEPWFLPPS RGLQNSPAVS LPDPEFKRDR KGPHPTARSP GTVMESNPQQ 1920
REGSSPKHQD HTTDPKLLTC LGQNLHSPDL ARPRCPLPPE ASPSREKPGL RESSERGPPT 1980
ARSERSAARA DTCREPSMEL CFPETAKTSD NSKNLLSVGR THPDFYTQTQ AMEKAWAPGG 2040
KTNHKDGPGE ARPPPRDNSS LHSAGIPCEK ELGKVRRGVE PKPEALLARR SLQPPGIESE 2100
KSEKLSSFPS LQKDGAKEPE RKEQPLQRHP SSIPPPPLTA KDLSSPAARQ HCSSPSHASG 2160
REPGAKPSTA EPSSSPQDPP KPVAAHSESS SHKPRPGPDP GPPKTKHPDR SLSSQKPSVG 2220
ATKGKEPATQ SLGGSSREGK GHSKSGPDVF PATPGSQNKA SDGIGQGEGG PSVPLHTDRA 2280
PLDAKPQPTS GGRPLEVLEK PVHLPRPGHP GPSEPADQKL SAVGEKQTLS PKHPKPSTVK 2340
DCPTLCKQTD NRQTDKSPSQ PAANTDRRAE GKKCTEALYA PAEGDKLEAG LSFVHSENRL 2400
KGAERPAAGV GKGFPEARGK GPGPQKPPTE ADKPNGMKRS PSATGQSSFR STALPEKSLS 2460
CSSSFPETRA GVREASAASS DTSSAKAAGG MLELPAPSNR DHRKAQPAGE GRTHMTKSDS 2520
LPSFRVSTLP LESHHPDPNT MGGASHRDRA LSVTATVGET KGKDPAPAQP PPARKQNVGR 2580
DVTKPSPAPN TDRPISLSNE KDFVVRQRRG KESLRSSPHK KAL 2624
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR015022--MA_Ser/Thr_Kinase_dom
IPR023142--MAST_pre-PK_dom
IPR001478--PDZ
IPR000719--Prot_kinase_dom
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS51285--AGC_KINASE_CTER
PS50106--PDZ
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF08926--DUF1908
PF00595--PDZ
PF00069--Pkinase

Gene Ontology

GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity