dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053469
Uniprot Accession J3QRB6; J3QRB6_HUMAN;
Genbank Protein ID XP_005257433.1;
Genbank Nucleotide ID XM_005257376.2;
Protein Name Mitogen-activated protein kinase kinase kinase 3
Protein Synonyms/Alias
Gene Name MAP3K3
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
55SSSALLNSPTVTTSSPhosphoSitePlus;curated22135298; 25627689
57SALLNSPTVTTSSCAPhosphoSitePlus22135298
277SRMSRAQSFPDNRQEcurated25627689
Sequence
(Fasta)		MDEQEALNSI MNDLVALQMN RRHRMPGYET MKNKDTGHSN RQKKHNSSSS ALLNSPTVTT 60
SSCAGASEKK KFLSDVRIKF EHNGERRIIA FSRPVKYEDV EHKVTTVFGQ PLDLHYMNNE 120
LSILLKNQDD LDKAIDILDR SSSMKSLRIL LLSQDRNHNS SSPHSGVSRQ VRIKASQSAG 180
DINTIYQPPE PRSRHLSVSS QNPGRSSPPP GYVPERQQHI ARQGSYTSIN SEGEFIPETS 240
EQCMLDPLSS AENSLSGSCQ SLDSPSFRKS RMSRAQSFPD NRQEYSDRET QLYDKGVKGG 300
TYPRRYHVSV HHKDYSDGRR TFPRIRRHQG NLFTLVPSSR SLSTNGENMG LAVQYLDPRG 360
RLRSADSENA LSVQERNVPT KSPSAPINWR RGKLLGQGAF GRVYLCYDVD TGRELASKQV 420
QFDPDSPETS KEVSALECEI QLLKNLQHER IVQYYGCLRD RAEKTLTIFM EYMPGGSVKD 480
QLKAYGALTE SVTRKYTRQI LEGMSYLHSN MIVHRDIKGA NILRDSAGNV KLGDFGASKR 540
LQTICMSGTG MRSVTGTPYW MSPEVISGEG YGRKADVWSL GCTVVEMLTE KPPWAEYEAM 600
AAIFKIATQP TNPQLPSHIS EHGRDFLRRI FVEARQRPSA EELLTHHFAQ LMY 654
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR000719--Prot_kinase_dom
IPR002290--Ser/Thr_dual-sp_kinase
PROSITE

PS51745--PB1
PS50011--PROTEIN_KINASE_DOM
Pfam

PF00564--PB1
PF00069--Pkinase
Gene Ontology

GO:0005622--C:intracellular
GO:0005524--F:ATP binding
GO:0004708--F:MAP kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0000165--P:MAPK cascade