dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053375
Uniprot Accession J3KNG9; J3KNG9_HUMAN;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Anion exchange protein
Protein Synonyms/Alias
Gene Name SLC4A2
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
31PRRRPGASPTGETPTcurated25849741
Sequence
(Fasta)
MSSAPRRPAK GADSFCTPGP GRKPRRRPGA SPTGETPTIE EGEEDEDEAS EAEGARALTQ 60
PSPVSTPSSV QFFLQEDDSA DRKAERTSPS SPAPLPHQEA TPRASKGAQA GTQVEEAEAE 120
AVAVASGTAG GDDGGASGRP LPKAQPGHRS YNLQERRRIG SMTGAEQALL PRVPTDEIEA 180
QTLATADLDL MKSHRFEDVP GVRRHLVRKN AKGSTQSGRE GREPGPTPRA RPRAPHKPHE 240
VFVELNELLL DKNQEPQWRE TARWIKFEED VEEETERWGK PHVASLSFRS LLELRRTLAH 300
GAVLLDLDQQ TLPGVAHQVV EQMVISDQIK AEDRANVLRA LLLKHSHPSD EKDFSFPRNI 360
SAGSLGSLLG HHHGQGAESD PHVTEPLMGG VPETRLEVER ERELPPPAPP AGITRSKSKH 420
ELKLLEKIPE NAEATVVLVG CVEFLSRPTM AFVRLREAVE LDAVLEVPVP VRFLFLLLGP 480
SSANMDYHEI GRSISTLMSD KQFHEAAYLA DEREDLLTAI NAFLDCSVVL PPSEVQGEEL 540
LRSVAHFQRQ MLKKREEQGR LLPTGAGLEP KSAQDKALLQ MVEAAGAAED DPLRRTGRPF 600
GGLIRDVRRR YPHYLSDFRD ALDPQCLAAV IFIYFAALSP AITFGGLLGE KTQDLIGVSE 660
LIMSTALQGV VFCLLGAQPL LVIGFSGPLL VFEEAFFSFC SSNHLEYLVG RVWIGFWLVF 720
LALLMVALEG SFLVRFVSRF TQEIFAFLIS LIFIYETFYK LVKIFQEHPL HGCSASNSSE 780
VDGGENMTWA GARPTLGPGN RSLAGQSGQG KPRGQPNTAL LSLVLMAGTF FIAFFLRKFK 840
NSRFFPGRIR RVIGDFGVPI AILIMVLVDY SIEDTYTQKL SVPSGFSVTA PEKRGWVINP 900
LGEKSPFPVW MMVASLLPAI LVFILIFMET QITTLIISKK ERMLQKGSGF HLDLLLIVAM 960
GGICALFGLP WLAAATVRSV THANALTVMS KAVAPGDKPK IQEVKEQRVT GLLVALLVGL 1020
SIVIGDLLRQ IPLAVLFGIF LYMGVTSLNG IQFYERLHLL LMPPKHHPDV TYVKKVRTLR 1080
MHLFTALQLL CLALLWAVMS TAASLAFPFI LILTVPLRMV VLTRIFTDRE MKCLDANEAE 1140
PVFDEREGVD EYNEMPMPV
Keyword

KW-0181--Complete proteome
KW-0406--Ion transport
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport

Interpro

IPR001717--Anion_exchange
IPR002978--Anion_exchange_2
IPR018241--Anion_exchange_CS
IPR013769--Band3_cytoplasmic_dom
IPR011531--HCO3_transpt_C
IPR003020--HCO3_transpt_euk
IPR016152--PTrfase/Anion_transptr

PROSITE

PS00219--ANION_EXCHANGER_1
PS00220--ANION_EXCHANGER_2

Pfam

PF07565--Band_3_cyto
PF00955--HCO3_cotransp

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0005452--F:inorganic anion exchanger activity
GO:0015701--P:bicarbonate transport
GO:1902476--P:chloride transmembrane transport
GO:0051453--P:regulation of intracellular pH