dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053342
Uniprot Accession I3L354; I3L354_HUMAN;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Runt-related transcription factor 2
Protein Synonyms/Alias
Gene Name RUNX2
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
14PSTSRRFSPPSSSLQcurated25849741
Sequence
(Fasta)
MRIPVDPSTS RRFSPPSSSL QPGKMSDVSP VVAAQQQQQQ QQQQQQQQQQ QQQQQQQEAA 60
AAAAAAAAAA AAAAAVPRLR PPHDNRTMVE IIADHPAELV RTDSPNFLCS VLPSHWRCNK 120
TLPVAFKVVA LGEVPDGTVV TVMAGNDENY SAELRNASAV MKNQVARFND LRFVGRSGRG 180
KSFTLTITVF TNPPQVATYH RAIKVTVDGP REPRNPRQAQ SSPPWSYDQS YPSYLSQMTS 240
PSIHSTTPLS STRGTGLPAI TDVPRRISAR SRYSLR 277
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000040--AML1_Runt
IPR008967--p53-like_TF_DNA-bd
IPR012346--p53/RUNT-type_TF_DNA-bd
IPR013524--Runt_dom

PROSITE

PS51062--RUNT

Pfam

PF00853--Runt

Gene Ontology

GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0002062--P:chondrocyte differentiation
GO:0030097--P:hemopoiesis
GO:0030182--P:neuron differentiation
GO:0045595--P:regulation of cell differentiation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter