dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0053317
Uniprot Accession I2HAA6; I2HAA6_CAEEL;
Genbank Protein ID NP_001256077.1;
Genbank Nucleotide ID NM_001269148.1;
Protein Name Uncharacterized protein
Protein Synonyms/Alias
Gene Name unc-68
Gene Synonyms/Alias CELE_K11C4.5;K11C4.5;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
1329LQEYKPRSQSVVSQIPHOSIDA;curated21081558; 18806794
1331EYKPRSQSVVSQIRAPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 18806794
1334PRSQSVVSQIRAPGIPHOSIDA;curated21081558; 18806794
1432WQDVLRRSLLELPHDPHOSIDA;curated21081558; 18806794
1499QMKANSRSFDAGSLDPHOSIDA;curated21081558; 18806794
1504SRSFDAGSLDTSTLPPHOSIDA;curated21081558; 18806794
2826PRALESDTALALNRYPHOSIDA;curated21081558; 18806794
3215NCPKDEQSQNDRLKSPhosphoPep 2.019060867
Sequence
(Fasta)
MDFDFTDISD EDHNYVTKGD IVCLSCVASH NRDGVLGSER VCLCTEGFGN RMCTLENVSD 60
KDIPPDIAMC MLYIDNALSM RALQEMMSAD SDHKSASGAG GHKTLLYGHA VQLKHVQSEM 120
YLACLSSCSS NDKLAFDVGV QETNEGEACW WTIHPASKQR SEGEKVRVGD DVILVSVATE 180
RYLHMAYSKG YMVIASFHQT LWNIQSVSSG SMRTRNMGFL FGNDVLRLFH GNDECLTIPE 240
NWSEHPQHNM VIYEGGAAVT QARSLWRVEL IRMKWHGALV GWEQVFRIKH ITSGRYLGVL 300
DNSVQLYHKE KADFDLTAFV MCQNKDPKKQ MLDEKEEEGM GNATIRYGET NAFIQHVKTQ 360
LWLSYQTTEV TKKGLGKVEE KKAVALKDGH MDDCYTFFMA LEEESKSARV IRKCSSVLNK 420
FLKGIDALQL EGNQSTDWTR VDLNEVLKLM EDLIEYFAQP NDEQDFEEKQ NHLRALRSRQ 480
DLFQEEGVLN MILDTIDKFS QMEALPDFAG LIGEETHVKW EQISTYLYLL VAAMIKGNHY 540
NCAQFASAQR LDWLFGRLSN PQSAEGILDV LYCVLTESPE ALNMINEGHI RSVISLLEKV 600
GRDPKVLDVL SSLCEGNGMA VRSSQNLITQ YLLPGKDLLL QTSMRDHVSS MMPNVMLGVV 660
EGSALFRKWY FEAEVEHIET MTKQTPYLRI GWANSVGFKP FPGSGDKMGC NGVGDDFYSY 720
GFDGKSMYFG GKSRRVGHKL LEKGDVIGCS IDLTIPEIKF SVNGTYMSGS FKKFNIDGYF 780
FPVMSLSAKV SCRFILGGNQ GRLRYGPPTG FSAVVEAVNG ELQITDCLSF GDLGKNIFSG 840
PQTIFNNLEP FIPTPIDVSA TQLNHHATEM HQKYAENLHE LWAMRKIELG WSYGETRSET 900
SRKHPCLTKF EYLPETEKKY NILLALTTMK TIEALGYHLI TEDPPCRLRA VRLGPNFQQQ 960
NGYKPGPLDT HEIQLPAELQ PLTEALARNT HNIWAKEKIK RGWTFGLSEH VDATQKRSPH 1020
LVPYEQVDER IKQANRESAA ENIRALQLFG IFLEPPAHEH DEVAEKELRA RKDNTRTYRA 1080
EATYAVCGGK WYFEFEILTA GYMKIGWMDI GSTPEIQLGA DDRSYAFDGY LGRKWHQGAE 1140
TYGKEWKIGD VVGCFLDLND RTISFSLNGE LLLDPSGSEM AFDNVVCGDG LVPAMTLGSG 1200
QRGRLNFGQQ SNSLKFFTTC GLQEGYEPFC VNMYRTMPMW FAKQLPRFED ISTLKSGSIL 1260
EVSRIPATGN SPPCLKILQK VTISEGGPSE KAKMEYIKLS LPVKCNDTFV KNKDKETIRR 1320
QLQEYKPRSQ SVVSQIRAPG IPKEFDDNKE KKGFLRSMLG SKDSHESDDD RRSRTNSKQP 1380
SVDGDEPPAV SQRRRVLTLM NFGMYSFDES ILTWLHVNEE DNHKWQDVLR RSLLELPHDE 1440
RQIAEDSMRD LNDRHSEKPK KGGLLSRLRD SSNTRKKDSD RRKEEKAAQL RQMKANSRSF 1500
DAGSLDTSTL PTGQKDVLEE ETEEQEPIWV MQDQFHDEDT VSASSEMPLS GPGRQLTIKR 1560
SSIKKNKKGK KAEIALEKME REKKGSIIPM DAQLDVLQEG DAHALVHHKD KVDEYYYGIR 1620
IFPGQDPSQV WVGWVTTQYH YYNVNFDGSQ GVRKCRFSEA DHHGTTVDSV QSQNCYMVNV 1680
SELLATTPDV ANTKVSGTLI GCIIDTSIGE LSFQVGSTDT GIKFKLEPGA MLFPAAFVTP 1740
TATEILQFEL GRIKYTFPLS AAMFKSCEKS LVPFCPPRLT VEQIESVYWA RVPNETLRTT 1800
ALKLSEVRGW SVLCNDPVRI MSVYIPEKDQ SLDILEMIEM PDMLEFHRQT LNLYCKLASH 1860
GNHKVAHTLC QHIDEDQIMY AIKSHYLSGP MRQGFHDLLI GLHLMSHTAA RNSMAKEYVI 1920
PLVPQLQIKN VLDPDSESRY PQITGESVSM LSQMASEPVK KHVSREDEMK LLPPSVDFEA 1980
LKKHVMESLQ SATHHAVMNC RDLIGGDNTN HFEPLFKLFD QLLVIGLIND EELECLLRLI 2040
HPQAFDENYE TGTTQKGLTQ LELAEPVKIQ LVSILDHLCD IQLRYRIESL VAFTEGFVGE 2100
LQSDQCKRYM EIKQTDMPPA EAAKKTKEFR CPPKEQMFRL LMCKVKEERD PELMEEDADV 2160
DQCPMAEGLQ QQLRDFCELL VGKIGNVKEG DSDDQLALIE SEEGSWVDSF ARIVVKVPPP 2220
VLEEGMEMQK KGTQNFREII VTMLREWAQA DFIESKSLIR NMFRLLLRQY SGIREIRDAM 2280
SQTYVFHERN EKDVTDFLVY LIQIRELLTV QFEHTEEAIL KRGLWKLMNN RIFFQHPDLM 2340
RLLSVHENVM SIMMNILTAQ QGTVEHEGDE LKEKAPIKDA SEMVVACSRF LCYFCRTSRQ 2400
NQKAMFEHLS FLLDNATMLL ARPSLRGSVP LDVAYSSFMD NNELALALKE EELDKVAVYL 2460
SRCGLQPNSE LITKGYPDIG WDPVEGERYI DFLRFCVWIN GENVEENANL VIRLLIRRPE 2520
CLGVALKGEG QGLFSAFKEA IALSEDIRLL ENDSHPSLLS SGLLGENPTY PSKDAEGEDY 2580
IDLGAATLDF YSSLVDLLAK CAPDPMAIQA GKGDSLRARA ILRSLISLDD LGQILALRFT 2640
IPNLAAPSIE AVRRANAVQA SHTQKAVMAH TFAMVASLAS EVSNTRRSQT FTSGTNLAKR 2700
GLPCVEEVDT DDSKSSDYAS VHTSFSSGNE LFAPKAEKEK VDVLKLNENK YPIIQRRRSS 2760
RFNPIDNTGP LPGLLPNHKG SVLLFLDRVY GIDQQDMLFH VLEQSFLPDL RAATMMDSPR 2820
ALESDTALAL NRYLCNSVLP LLTNHSHFFA DAEHHSALLD ATLHTVYRMN RLKSLTKNQR 2880
DAVSDFLVAI TRELPPAMMI KLLKKVITDI LTMNDMNVLV PLRLITLHYE RCGKYYGSGN 2940
HYGVASEQEK RLSMLLFDAI FDTLGSRPYD PELFGKALPC MTAIGSAISP DYTLTSGLED 3000
VRNKRREEEG AWIPRTVDVS RCEINRDLEK MTELFAEHFH DSWASRKLEK GWVHGDLYSR 3060
ANFTHPRLKP FALLKDFEKS FYKERCSECL KALMAWNYSF EMMDRDANDR ASAARTLSGT 3120
SISNFAPKPI DLSSMTLEKD MVNAAEKMAE HSHLIWAKKV MNDLNTKGGF MPIPLVPWDL 3180
LTDFERRKDR FRASEILKFL QYHGYHVNCP KDEQSQNDRL KSEGERTSVE KRFAYNLLEK 3240
LITYLEQASL KMKSVKPSQE LTRRNSFKKE GQDVKFFEKV VLPLMHAYFN AHKNYFLEGS 3300
SIVQTGTASN KEKEMVANLF CRLAALLRIK NRAFGSVAKI TVKCLQGLTQ ALDLRTLVKV 3360
NSDIVRTSLL TFFNNCADDL YASVNELKKC IYYSEIEEYD DGGQYSLIRG QALKSWNSFE 3420
FANQMIVPVL TTMFAHLARN HFGTDLLLDD IQAACYKILD SLYMVTGLSS SISHRKSISG 3480
ESEKHRPGLG QCLAAFASCF PVAFLEPEFN KSNKFSVLAK SQDQSVQVQE MLQNLSTHIP 3540
HLEKLLTDLE TVANNNTMYS DVPNVYDVDL PLMCSYMAHW FSVGPDGKRD KEDQRASVVQ 3600
TTSVSCDHIN RIFNALLKMI RNHVGIENAP WLCRVNFFAV QIIQNVTSDP VREFVLPIAE 3660
RLRRMSEKAY KEEEHMRTHP DDADEGTVAE DNARLVRDTY AFFPILMKYT DLHRAQWLKT 3720
PTWETDGVYE NVAVIFRIWS QSQHFKREEL NYVAQFEEDA AATGGGDMKT GKAAIAERKK 3780
KRREGQDKMK EYFDRNGRPI IKKDKHAASI VIACLKRLLP VGLNVFGGRE LDIVQQSKEK 3840
FIQKETEEKI REFIKGLLEI PVKTDPTDKN AWQLSLYRKI GKSQMRGKDE MSQDAVIEKI 3900
FNMGQVSAIL HTITRTKDRR RRAHHRWKYN RKNINIAQVN HSDRNVVLSI SCYVLSHLDG 3960
ASANATVASM EKSGLDATKT CRCGVFPHGS TVWNSKMTSR MEKEDIWKKV LTLQRKRMAI 4020
SLITASHLYK TELHRGINFF LPAFSRLWME EEDAGQDQLI ADICSGVEEE EGPRIEIIME 4080
EGVPIVASSE DTKEKETNPD PLKQLIRCFQ RAATSEETAA SAIHEDSLYI RFADVMAKSI 4140
HIEEEDGEDG EEGEIDQAAK EEQSQALRGE QAVLASRGAA IMCLMYLSAS GGEPNEMVAQ 4200
TLQLGIHLLS GGNVEIQKML IEYLQLKKDV RFFTSMAGLM NKCSVLNLEM FERQIKNVDA 4260
HGANELLLRH LSSKIRHRSR QDRLGAQAEG LGMGAELASG DNQNLNDADF TCSLFRFLQL 4320
TCEGHNLEFQ NYLRTQPGHT TSVNLINCTV DYLLRLQESV MDFYWHYSSK EVIDEGGKEY 4380
FLRAIQVCSQ VFNTLTESIQ GPCVGNQMTL ANSRLWDAIN GFFFLFAHMM EKLYKNSTQL 4440
ELLREFLNLQ KDMIVLMLSM LEGNVLNGSI GKQMVDALVE SQPSVEKILK FSDMFLKLKD 4500
LTTSQAFQDF DTNQDGWISP KEFQRAMESQ KMYTVEDITY LMMCTDVNND GKVDYMEFTE 4560
RFHNPARDIG FNLAVLLVNL KEHITNDPRL EKIIEKAQTL LEYFDPFLGR IEIMGSSKRV 4620
EKIYFEIQES WLEQWGKQQI RDSKNSFLFN VLQDDGGDQG KLEAFINFCE DTIFEMQHAA 4680
AISSGDSDTK MERAIKQRDY FLQQTSADHI SETFKSGYNY GISAASALSP QNISTTMRNV 4740
SSSVRQMSWT QLLYAVIILF IRAGLAIGWA GYLLLMTIFR FGYFLTTSSE EEEAARQEKE 4800
QAKMNNEHPS FNPPIIQEFH HSHVGVTAFG VGMNADHLNV NSLPDFVPPE RPETPETVLE 4860
EEKPLNQETS PPTSPTSPAS KAPSIYESIG APQMVQLQSE ADFQQGQYEP KIAESNSTKS 4920
RGSILNMLAR NFKTIEKITL YLAFFINVIL LFHRVDISHA ENAEAASEGD DDEDALESIF 4980
ITGMQFPYVE YEITGWMLAQ ILYWISVLHL STSFALLVSF YQLKIPLITF KREKEIARKL 5040
MFDGCWITEE DSEELGIVDT FMWYLDRIVV SAKSFPMMYW DKFVRRKTRS KFKDQVDEET 5100
LTSILGEEKM STDSSYDYRY SCWLWIGVIL TNGQFLYRVG YLLCSACGVF LSPFFYAFHL 5160
IDVVLSFPML KAILQSVTHN LQQLILTIMM TLVVVYLYTV IAFNFFRKFY VQEGEEGEEP 5220
DRKCHNMLTC FIYHFYAGVR AGGGIGDELE SPYGDDLEYP RMFYDISFFF FVIIILLAIM 5280
QGLIIDAFGE LRDQQESATE KLESSCFICD IGKETFDRMP RGFEIHTTKE HNFANYLFFL 5340
QHLVNKDETE YTGQETYVRE KYDNRDWDFF PVGECFVKQY EDQLLQS 5388
Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0407--Ion channel
KW-0406--Ion transport
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport

Interpro

IPR001870--B30
2/SPRY--
IPR013320--ConA-like_dom
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR014821--Ins145_P3_rcpt
IPR005821--Ion_trans_dom
IPR016093--MIR_motif
IPR013662--RIH_assoc-dom
IPR000699--RIH_dom
IPR013333--Ryan_recept
IPR003032--Ryanodine_rcpt
IPR015925--Ryanodine_recept-rel
IPR009460--Ryanrecept_TM4-6
IPR003877--SPRY_dom

PROSITE

PS50188--B302_SPRY
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50919--MIR

Pfam

PF13499--EF-hand_7
PF08709--Ins145_P3_rec
PF00520--Ion_trans
PF02815--MIR
PF08454--RIH_assoc
PF06459--RR_TM4-6
PF01365--RYDR_ITPR
PF02026--RyR
PF00622--SPRY

Gene Ontology

GO:0031674--C:I band
GO:0016021--C:integral component of membrane
GO:0005509--F:calcium ion binding
GO:0005219--F:ryanodine-sensitive calcium-release channel activity
GO:0006874--P:cellular calcium ion homeostasis
GO:0040011--P:locomotion
GO:0043068--P:positive regulation of programmed cell death
GO:0033365--P:protein localization to organelle