dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053248
Uniprot Accession H7C3C4; H7C3C4_HUMAN;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Anion exchange protein
Protein Synonyms/Alias
Gene Name SLC4A7
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
14AEKIVLLTSARFLFLPHOSIDA21081558
15EKIVLLTSARFLFLLPHOSIDA21081558
743LKYSVDPSIVNISDEPhosphoSitePlus;curated22135298; 25627689
748DPSIVNISDEMAKTAPhosphoSitePlus;curated22135298; 25627689; 22199227
761TAQWKALSMNTENAKPhosphoSitePlus;curated22135298; 25850435; 25627689
772ENAKVTRSNMSPDKPPhosphoSitePlus;curated22135298; 23090842; 20068231
775KVTRSNMSPDKPVSVPhosphoSitePlus;SysPTM 2.0;curated22135298; 18669648; 19366988; 25627689; 23911959; 23090842;
781MSPDKPVSVKISFEDPhosphoSitePlus;SysPTM 2.0;curated22135298; 18669648; 19366988; 25627689; 23911959; 22199227;
785KPVSVKISFEDEPRKPhosphoSitePlus;curated22135298; 23836654
Sequence
(Fasta)		VMEVVEAEKI VLLTSARFLF LLLGPAGKAP QYHEIGRSIA TLMTDEIFHD VAYKAKDRND 60
LLSGIDEFLD QVTVLPPGEW DPSIRIEPPK SVPSQEKRKI PVFHNGSTPT LGETPKEAAH 120
HAGPELQRTG RLFGGLILDI KRKAPFFLSD FKDALSLQCL ASILFLYCAC MSPVITFGGL 180
LGEATEGRIS AIESLFGASL TGIAYSLFAG QPLTILGSTG PVLVFEKILY KFCRDYQLSY 240
LSLRTSIGLW TSFLCIVLVA TDASSLVCYI TRFTEEAFAA LICIIFIYEA LEKLFDLGET 300
YAFNMHNNLD KLTSYSCVCT EPPNPSNETL AQWKKDNITA HNISWRNLTV SECKKLRGVF 360
LGSACGHHGP YIPDVLFWCV ILFFTTFFLS SFLKQFKTKR YFPTKVRSTI SDFAVFLTIV 420
IMVTIDYLVG VPSPKLHVPE KFEPTHPERG WIISPLGDNP WWTLLIAAIP ALLCTILIFM 480
DQQITAVIIN RKEHKLKKGA GYHLDLLMVG VMLGVCSVMG LPWFVAATVL SISHVNSLKV 540
ESECSAPGEQ PKFLGIREQR VTGLMIFILM GLSVFMTSVL KFIPMPVLYG VFLYMGVSSL 600
KGIQLFDRIK LFGMPAKHQP DLIYLRYVPL WKVHIFTVIQ LTCLVLLWVI KVSAAAVVFP 660
MMVLALVFVR KLMDLCFTKR ELSWLDDLMP ESKKKKEDDK KKKEKEEAER MLQDDDDTVH 720
LPFEGGSLLQ IPVKALKYSV DPSIVNISDE MAKTAQWKAL SMNTENAKVT RSNMSPDKPV 780
SVKISFEDEP RKKYVDAETS L 802
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0406--Ion transport
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
Interpro

IPR013769--Band3_cytoplasmic_dom
IPR011531--HCO3_transpt_C
IPR003020--HCO3_transpt_euk
IPR003024--Na/HCO3_transpt
IPR016152--PTrfase/Anion_transptr
PROSITE
Pfam

PF07565--Band_3_cyto
PF00955--HCO3_cotransp
Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0005452--F:inorganic anion exchanger activity
GO:0008510--F:sodium:bicarbonate symporter activity
GO:0098656--P:anion transmembrane transport
GO:0060117--P:auditory receptor cell development
GO:0015701--P:bicarbonate transport
GO:0051453--P:regulation of intracellular pH
GO:0035725--P:sodium ion transmembrane transport