| Tag |
Content |
| dbPAF ID |
dbPAF-0053188 |
| Uniprot Accession |
H7BY38; H7BY38_HUMAN;
|
| Genbank Protein ID |
|
| Genbank Nucleotide ID |
|
| Protein Name |
Cytochrome P450 2D6 |
| Protein Synonyms/Alias |
|
| Gene Name |
CYP2D6 |
| Gene Synonyms/Alias |
|
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 56 | ILGFGPRSQGRPFRP | PhosphoSitePlus | 22135298 |
|
Sequence
(Fasta) | LRRRFGDVFS LQLAWTPVVV LNGLAAVREA LVTHGEDTAD RPPVPITQIL GFGPRSQGRP 60
FRPNGLLDKA VSNVIASLTC GRRFEYDDPR FLRLLDLAQE GLKEESGFLR EVLNAVPVLL 120
HIPALAGKVL RFQKAFLTQL DELLTEHRMT WDPAQPPRDL TEAFLAEMEK WWLTCSLPGW 180
181Fasta Sequence
>H7BY38|CYP2D6|Homo sapiens(Human)
LRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKWWLTCSLPGW
|
| Keyword |
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
|
| Interpro |
IPR001128--Cyt_P450
IPR002401--Cyt_P450_E_grp-I
IPR008069--Cyt_P450_E_grp-I_CYP2D-like
|
| PROSITE |
|
| Pfam |
PF00067--p450
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0008392--F:arachidonic acid epoxygenase activity
GO:0020037--F:heme binding
GO:0005506--F:iron ion binding
GO:0016712--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0019825--F:oxygen binding
GO:0008395--F:steroid hydroxylase activity
GO:0019369--P:arachidonic acid metabolic process
GO:0042738--P:exogenous drug catabolic process
|
