dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053081
Uniprot Accession H3BIW6; H3BIW6_MOUSE;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Phosphoinositide phospholipase C
Protein Synonyms/Alias
Gene Name Plch2
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
1044QPRARVDSLGGPCCSPhosphoSitePlus22135298
1092SSPDSPGSPKVAPCQPhosphoSitePlus22135298
Sequence
(Fasta)		MEEPGPPGGL SQDQVERCMS AMQEGTQMVK LRGSSKGLVR FYYLDEHRSC LRWRPSRKNE 60
KAKISIDSIQ EVSEGRQSEI FQRYPDSSFD PNCCFSIYHG SHRESLDLVS PSSEEARTWV 120
TGLRYLMAGI SDEDSLARRQ RTRDQWLKQT FDEADKNGDG SLSISEVLQL LHKLNVNLPR 180
QRVKQMFREA DTDDHQGTLG FEEFCAFYKM MSTRRDLYLL MLTYSNHKDH LDASDLQRFL 240
EVEQKMNGVT LESCQNIIEQ FEPCLENKSK GMLGIDGFTN YTRSPAGDIF NPEHNRVHQD 300
MTQPLSHYFI TSSHNTYLVG DQLMSQSRVD MYAWVLQAGC RCVEVDCWDG PDGEPIVHHG 360
YTLTSKILFK DVIETINKYA FIKNEYPVIL SIENHCSVVQ QKKMAQYLTD ILGDKLDLSS 420
VSSEDATMLP SPQMLKGKIL VKGKKLPANI SEDAEEGEVS DEDSADEMED DCKLLNGDAS 480
TNRKRVENIA KKKLDSLIKE SKIRDCEDPN DFSVSTLSPS GKLGRKAEAK KGQSKVEEDV 540
EAGEDSGVSR QNSRLFMSSF SKRKKKGSKI KKVASVEEGD ETLDSPGSQS RGTARQKKTM 600
KLSRALSDLV KYTKSVGTHD VEIEVVSSWQ VSSFSETKAH QILQQKPTQY LRFNQHQLSR 660
IYPSSYRVDS SNYNPQPFWN AGCQMVALNY QSEGRMLQLN RAKFSANGDC GYVLKPQCMC 720
QGVFNPNSED PLPGQLKKQL ALRIISGQQL PKPRDSVLGD RGEIIDPFVE VEVIGLPVDC 780
SKEQTRVVDD NGFNPMWEET LVFTVHMPEI ALVRFLVWDH DPIGRDFIGQ RTLAFSSIMP 840
GYRHVYLEGM EEASIFVHVA VSDISGKVKQ TLGLKGLFLR GTKPGSLDSH AAGQPLPRPS 900
VSQRLLRRTA SAPTKSQKPS RKGFPELALG TQDAGSEGAA DDVAPSSPNP ALEAPTQERS 960
GSSSPRGKAP GGEATEERTL AQVRSPNAPE GPGPAGMAAT CMKCVVGSCA GMDVEGLQRE 1020
QQPSPGPAGS HMAISHQPRA RVDSLGGPCC SPSPRATPGR SKEAPKGPRA RRQGPGGGSV 1080
SSDSSSPDSP GSPKVAPCQP EGAHRQQGAL QGEMNALFVQ KLEEIRSHSP MFSTVRD 1138
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0807--Transducer
Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR028393--PLC-eta2
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR015359--PLC_EF-hand-like
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
PROSITE

PS50004--C2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
Pfam

PF00168--C2
PF13499--EF-hand_7
PF09279--EF-hand_like
PF16457--PH_12
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
Gene Ontology

GO:0005622--C:intracellular
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004629--F:phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0035556--P:intracellular signal transduction
GO:0016042--P:lipid catabolic process
GO:0046488--P:phosphatidylinositol metabolic process