dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0053019
Uniprot Accession H2KZU7; SVH2_CAEEL; H1AGA1; Q6AHP3;
Genbank Protein ID NP_001024906.1; NP_509104.1; NP_509105.1;
Genbank Nucleotide ID NM_001029735.3; NM_076703.6; NM_076704.4;
Protein Name Tyrosine-protein kinase receptor svh-2
Protein Synonyms/Alias Met/Ron-like receptor tyrosine kinase svh-2;Suppressor of vhp-1 deletion lethality protein svh-2;
Gene Name svh-2
Gene Synonyms/Alias T14E8.1;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)		 Receptor tyrosine kinase which may phosphorylate mlk-1, a component of the mlk-1, mek-1 and kgb-1 pathway. Involved in axon regeneration after injury by promoting the generation of productive and stable growth cones.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
890VDIETELYVQMHERDUniProt22388962
Sequence
(Fasta)		MVLGSSQSSA KELTTQSSIF RFLVLLLCFT SATGGQINGK LLNGNGVFVS RDELQNKNVL 60
GVITGFDLLV VATHSRFQVF ENNEERRTVG HVSLDMHPRT KFLELKLFSK SEIFYCDESS 120
CGLCTYSGVT SSCSTFMLNG DEPKIQEILS SSAVKIENLG QIMLAISFKN EEDPDNPRTM 180
ILRYNAQDTG TVIPTAYHAD SSFIHNNHAL TGFEREGFVY FVMTASQIFE PEVFLHDQSN 240
NKVTVTKVIR FCATDQTADL ASKISILVGC DQEFRNISSR GETAVYDHAN DLINIVMFNH 300
TSMNHLMCRF KMANIEKRFK TIWSTCQETS FSGSTAKTTR CKYPQIFDQM KVKKGCLTYS 360
RLDDESSPTL CVRYGRGDAL DNCQLHTAKS NSYRYGWLED YNVLQGELMM RIPYPFFGIA 420
ESLITDGKSY FAAVSGEFDM SDVLRFSASE SADIRPHWRT NISVVGKFSI TKTKENQLLY 480
TTVEGLQSLD ISCKGLYPNC QTLRQGGWED PLECSWCADD NAQRTITSSE VSSCKNNLKH 540
ECPPSMRWIH KYNNNSGFTA VVDGFRALKN PKLNACGTNC VVTVVDSSSI QCDTNPDEVI 600
GDSCKQVFLS GMIGDKNYSF PFDYQQADRG TQTDVKNSQV DDKKGSSPGW KIAIAIISVM 660
TIILIVAIIV YYMRNRFPRI KTHVRPPIGQ RIENEYDMGH MAGRQAQLAI NGDNYVKVFR 720
SMRPDLKVDF KNLRVDKLDP IGQGHYGVVY KAMYSPSKSL EEKVVCKYLK EGKISEFYEE 780
ARTMSEFDHP NILKLIGVAL DDSSHLPIII TEYMAKGDLK SFIENVENTI KMRDLFEFAF 840
DIAKGMNYMH SKKFIHRDLA CRNCLLDEHL RVKIADFGLC RKVDIETELY VQMHERDLPV 900
RWFPPEISEQ GFGITSDIWS FGVVIWELFT RGSTPYSNMA SWILILPWLK ESETNRLRKP 960
PYCPEKLYTD VMLACWKANP AERPQFSDLV TIIPNVVKYM EGYDRSQLQA GYERVSSRFL 1020
SLSRHDPAFP IYQNEMPNTP LLANCQNDTN DSKTLAELPS DSPSTSTAIP QSTPYQLLSE 1080
CSETSV 1087
Keyword

KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0418--Kinase
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0675--Receptor
KW-1185--Reference proteome
KW-0732--Signal
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0829--Tyrosine-protein kinase
Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001627--Semap_dom
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
Pfam

PF07714--Pkinase_Tyr
Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004714--F:transmembrane receptor protein tyrosine kinase activity