dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052997
Uniprot Accession H2KZC3; H2KZC3_CAEEL;
Genbank Protein ID NP_001255279.2;
Genbank Nucleotide ID NM_001268350.2;
Protein Name K+/Cl-Cotransporter
Protein Synonyms/Alias
Gene Name kcc-2
Gene Synonyms/Alias CELE_H16O14.1;H16O14.1;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
68NTVTSRRSSGGSGSGPhosphoPep 2.019060867
69TVTSRRSSGGSGSGLPhosphoPep 2.019060867
117LYEQDYDTQGQKIGTPHOSIDA;curated21081558; 18806794
130GTMLRKLSVYNATEAPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 18806794
1016EEQEDGKSENGSAKIPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 18806794
1020DGKSENGSAKIEHKGPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 18806794
1031EHKGVRFSDDEDSKEPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 18806794
1045EVKVGNGTLERDREEPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 18806794
Sequence
(Fasta)		MSGGRFRVQS VADGGGGGAG SVGALDSVSD SNLAVNSATK KEITNKAHDF EPEPTSSTST 60
NTVTSRRSSG GSGSGLGPAS KKPPNMHINI PTDEGAERIP LCEQHSPLAL YEQDYDTQGQ 120
KIGTMLRKLS VYNATEATSV EADEKPKAAA AKMGTIMGVF LPCLQNIFGV LFFIRLAWII 180
GTAGVFQAFF VVLTCVSVTF LTSISLSAIA TNGVVPSGGP YYMISRNLGP ELGGAVGILF 240
YLGTTIAASM YITGAIEILL LYIYPQAKLF DDIYHNFRVL GTVLLLILGL IVMAGVKFVN 300
RCALPLVIVV ILCILSAILG VFVRYDGSDS LKFCMVGDRP VDLSTYFEKT QVQPNCTADG 360
LQDLFCSTNG TCDHYYDRMK NIKVWKSSGM PAIREERAIK GIASGVFFDN LWPKYLRAGE 420
VLSKDRKDKG DLNRGGHPSY IYAESVTNFM ILVGVFFPSA TGIMAGSNRS GNLRDAAKSI 480
PLGTLAAQNF SSFIYLLGVV LFGASVSEMF IRDKYGRSAM GKLIISEISW PFPQVILFGC 540
FMSTAGAGMQ SLTGAPRLLQ AIAADDVLPF LKPFRKMDSR GEPIRAILLT LAICECGILI 600
AVIENITALI TQFFLMCYLG VNAACALQSL LKSPGWRPGF RYFHWSLSMI GAILCVAVMF 660
ISAWHFALFA IIIGAGVYKY IEYAGAEKEW GDGLRGLGLS AARFALLNLD DKPQHSRNWR 720
PQLLVLAPDV ESANTNGILS FVSQLKAGKG LTLVAHCMEG EYADNYLKAQ AVQEKLKAVV 780
KKNKIKGFCD VLVTSNVIEG ISCLVQTSGL GGMRHNTVVL SWPNDWKAEQ EWVVANKFVS 840
AIRAISAAKC AIMVPKYAEK FPANGTKVSG FIDVWWVVHD GGLLMLLPFL LRQHKTWKNT 900
TVRLFAIAQM EDNNVQMKTD LEKFLYHLRI DAAVNVIEMT DSDISDYTYE RTMKMEERNQ 960
YLKNLNKSDR DKDIQNHLEI VTRERKLSRI NEEAPAVVPE QRNLEVVDEE QEDGKSENGS 1020
AKIEHKGVRF SDDEDSKEVK VGNGTLERDR EERQRKRRYN VHKMHTAVKL NELMRQKSSD 1080
AQLVFVNLPG PPDADSDSYY MDFIEALTEG LDRVLLVRGT GAEVVTIYS
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR004841--AA-permease/SLC12A_dom
IPR018491--SLC12_C
PROSITE
Pfam

PF00324--AA_permease
PF03522--SLC12
Gene Ontology

GO:0016021--C:integral component of membrane
GO:0022820--F:potassium ion symporter activity
GO:0006821--P:chloride transport
GO:0071805--P:potassium ion transmembrane transport
GO:0006813--P:potassium ion transport
GO:0032228--P:regulation of synaptic transmission, GABAergic