dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052959
Uniprot Accession H2KYP2; H2KYP2_CAEEL;
Genbank Protein ID NP_504414.4;
Genbank Nucleotide ID NM_072013.7;
Protein Name Na/Ca eXchangers
Protein Synonyms/Alias
Gene Name ncx-2
Gene Synonyms/Alias C10G8.5;CELE_C10G8.5;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 13
PositionPeptidesSourceReferences ( PMIDs )
251PHRYRRGSHGQMIATPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
611RMERKRGSSVASESKPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
612MERKRGSSVASESKDPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
615KRGSSVASESKDSNTPhosphoPep 2.0;curated19060867; 18806794
617GSSVASESKDSNTENPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
637EKSTRAASVDLLQPSPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
650PSSDPRRSSQTNSPHPhosphoPep 2.019060867
651SSDPRRSSQTNSPHLPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
653DPRRSSQTNSPHLTSPhosphoPep 2.019060867
655RRSSQTNSPHLTSRFPhosphoPep 2.019060867
660TNSPHLTSRFRNRLGPhosphoPep 2.019060867
668RFRNRLGSWIAGMKGPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
689VTTSLTPSQLEIAEMPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
Sequence
(Fasta)		MTRLGCWLAV AFLVALAGLA DAGSNCSAAD ATRNCIDGLV IPIWRPFLDL TTGDRVLRGV 60
LYFFVIAYMF LGISIVADRF MSSIEVITSM ERTIVVKRPG LDPMAVQVRI WNDTVSNLTL 120
MALGSSAPEI LLSIIEVIAR GFEAGDLGPN TIVGSAAFNL FMIIAICVVV IPKGEIRRQK 180
HLDVFCVTAT WSVFAYVWLY LILAFFSPGE IEIWEGALTF IFFPLTVFTA YMADIKLIQN 240
KFLPHRYRRG SHGQMIATEA EEMKMLENGT QGDPALKAFE EHRQEFIELM REIRKQNPHI 300
TPTELQKQAE YEMISRGPKS RAFYRVQATR RLIGGGDIVK KRIDKEHNKA LDAAQEKQSR 360
DNTCKIFLDP AHYTVLESVG SFDVVVGRDG GPDGLTVMVD YFTEDGSANA GSDYIPVKGT 420
LTFYPEDKHQ KVTIEVVDDD VFEEDEHFYL RLCNLRVRTK DGIIIDPTRI GGLPVAQLEM 480
PNTATIMILD DDHAGVFGFE HDHFQVVENC GHLSLQMKRH SGARGKVIIP FRTVEGTASA 540
DKHFEMKEGE IVFEDNQTEA LVEIGIVDTE QYERSDYFYI ELSPPIWAKK MNDLSRIQER 600
FQRRMERKRG SSVASESKDS NTENALAPAE KSTRAASVDL LQPSSDPRRS SQTNSPHLTS 660
RFRNRLGSWI AGMKGGNGDD EVTTSLTPSQ LEIAEMGKPR LGEFTKCQIT IRESKEFQGI 720
VDRMIKNANT RIMLGTHSWR EQFMEALVVS AGDDDDDEGE DGEDGEEKEP EEPGCMDYVM 780
HVLTVPWKLT FATIPPTDYF GGWATFVVAI FMIGVLTAVV GDLASQFGCW VGLKDAVTAI 840
SFVALGTSVP DTFASKVSAV QDKYADNAVG NVTGSNAVNV FLGIGIAWSM AAIYHWNQGT 900
KFLVDPGNLG FSVLIFCTEA VLCIIVLVLR RNKKVGGELG GPIALRWMTA MFFASLWFMY 960
LLLSALEAYC IIPGF 976
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR003644--Calx_beta
IPR004836--Na_Ca_Ex
IPR032452--Na_Ca_Ex_C-exten
IPR004837--NaCa_Exmemb
PROSITE
Pfam

PF03160--Calx-beta
PF01699--Na_Ca_ex
PF16494--Na_Ca_ex_C
Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005432--F:calcium:sodium antiporter activity
GO:0007154--P:cell communication