dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0052957
Uniprot Accession H2KYN6; H2KYN6_CAEEL;
Genbank Protein ID NP_001023909.2;
Genbank Nucleotide ID NM_001028738.4;
Protein Name SMEK (Dictyostelium Suppressor of MEK null) homolog
Protein Synonyms/Alias
Gene Name smk-1
Gene Synonyms/Alias CELE_F41E6.4;F41E6.4;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 14
PositionPeptidesSourceReferences ( PMIDs )
293TFDDGDDSDVGEMPSPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
834SEDNSLASPRSFRKDPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
871EKDSVAVSPKKEEAGPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
936RSPSRTPSPASSPRAPhosphoPep 2.019060867
945ASSPRASSSPGPSRDPhosphoPep 2.0;curated19060867; 18806794
946SSPRASSSPGPSRDDPhosphoPep 2.0;curated19060867; 18806794
950ASSSPGPSRDDEVTSPhosphoPep 2.019060867
958RDDEVTSSQNNKESSPhosphoPep 2.019060867
964SSQNNKESSPTPTVKPhosphoPep 2.019060867
965SQNNKESSPTPTVKSPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
967NNKESSPTPTVKSLVPhosphoPep 2.019060867
969KESSPTPTVKSLVDYPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
1014ADGKKGDSPEYNDVSPhospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 21081558; 19060867; 18806794
1017KKGDSPEYNDVSSTSPhosphoPep 2.019060867
Sequence
(Fasta)		MSDTKEVSDD PMELGTSSTV IAKEENDKES LKRMEVDDEK EPEEEIVEKT EEKQEEEDVT 60
VKLEDETETE VESVDGGQEE KEVVDEKQVD AERVNTKTEE LSPKKEVKAE EDPETETKKK 120
DPSEQTNGQV KKKSDKQSPK KKEKSEGKEN SPGSKLTNRD HILDHLDIKR DATNRVKLYV 180
LCDQRIWEDR GTGHVVTHQL SAEDGAPSNA GNTMVLVRLE GQNKNMLESR IQMDTVYQKQ 240
QETLIVWSET DVMDLALSFQ EKSGCEELWQ KICEVQGRDP GDPDATFDDG DDSDVGEMPS 300
SASRLQLPPI EIGRLGELDA LLHMHLTTNS AREKMTLAIE NDNVVTKLCE VFRMCEDIEH 360
TEGLRTFYSI VKNLFMLNRN TVIEMLLDDN NIKDVIGMFE FDPAYKHPRK HRDFVYKKAK 420
FREVLNISCD ELRDKIHRLY RAQYIQDACL PSLGLFEENL LSTLSSHVFF CRVDIVTLLQ 480
KDKKAMSELF GQLISEETDV IRRRDLALFL KEMISLSTSI PSNGPAATKE TFFKLQLQNM 540
FNSEILDSLE PCFKSPDHET RAVMVDVLRT MVDANAQMIR DFLLKQSKTK DKNEDVLLNM 600
MIRHLLTDID VHLTSGSEIV LIMKTLLDPE NMTTVKSERS DFLQLFYNRC YESLLKPILE 660
NVSGGNIKKD DYMIANRQSV ILRLLTFCVE HHSFSMRQRC VSNDLMNKVL VLLKSKHSFL 720
VLSALKLLQR VVTVKDDKYI RYIVKEKVLD PVMECFRKNG NRYNIINSSV LHLFEFVRSE 780
DVRPLIKYVV ENHMEVVDSV NYVKTFKEIK IRYDQHRDRE ETMSVRSEDN SLASPRSFRK 840
DRNEDQWFDE DEDLEVGTML ESIEKDSVAV SPKKEEAGQR KTGMEPMFPS LLKRKNAFDD 900
DEAPVFGGGS AAVINNTEKK IVIKVNSDRS PSRTPSPASS PRASSSPGPS RDDEVTSSQN 960
NKESSPTPTV KSLVDYDESD DSDDDPPSPD AVPSSSTGSP EKEGDSADGK KGDSPEYNDV 1020
SSTSNEEKFD SRNGAPVTNE NGGVEAAAPT VEISRKRTSD GIDPDAKRIR TEETAPAATA 1080
TVSQA 1086
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR016024--ARM-type_fold
IPR006887--DUF625
PROSITE
Pfam

PF04802--SMK-1
Gene Ontology

GO:0005634--C:nucleus
GO:0006974--P:cellular response to DNA damage stimulus
GO:0042742--P:defense response to bacterium
GO:1904290--P:negative regulation of mitotic DNA damage checkpoint
GO:0009411--P:response to UV
GO:0010165--P:response to X-ray